Neoplastic Disease
Neoplasms of the CNS in goats are rarely found in large- scale surveys of neoplastic disease of livestock. For example, there was one caprine neoplasm, a spongioma, in a report on 400 tumors of the nervous system of domestic animals (Luginbuhl 1963).
However, some individual cases have been reported in the literature. In Germany, a 15-year-old female goat that suddenly developed a right-sided head tilt that progressed to loss of orientation and ataxia was subsequently euthanized and found to have a choroid plexus carcinoma, which manifested as a well-circumscribed mass in the left ventricle that compressed the cerebrum and infiltrated the left piriform lobe (Klopfleisch et al. 2006). In a report from North Carolina, glioma was diagnosed in a 6-year-old castrated male, mixed-breed goat that presented with a one-week history of circling, behavioral change, decreased appetite, and adipsia. A CT scan identified a large cerebral mass, which was confirmed at necropsy as a glioma (Marshall et al. 1995). Lymphosarcoma (Craig et al. 1986) and malignant melanoma (Sockett et al. 1984; Sinnott et al. 2020) have also been reported involving the nervous system in goats. A malignant Schwannoma of peripheral nerve sheaths, manifesting as 0.5-2 mm nodules, was identified in the diaphragm of a 2-year-old female goat at slaughter in Spain (Ramirez et al. 2007).A goat with cerebral gliomatosis was identified in a survey of small ruminant field cases with clinical presentations of neurologic disease carried out in support of Swiss scrapie surveillance activities. The goat also had hair lice and the combination

Figure 5.8 A 2- day- old kid with hydrocephalus. The kid was dull and depressed at birth and could only stand when assisted. It preferred the curled, recumbent position, as shown in (a).
Doming of the skull was not prominent, but distension of the ventricular system was evident at time of necropsy (b). Source: Courtesy of Dr.T.P. O'Leary.
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