PREVENTION
The widespread distribution of feral cats across Australia means environmental contamination of infective oocysts is ubiquitous. As such, attempts to limit the disease that focus on control or management of feral cats are likely to be unsuccessful.
In the managed care setting, exposure can be minimised by preventing cats from accessing enclosures or preventing faecal contamination of food and water sources. Attempts to vaccinate tammar wallabies (Notamacropus eugenii) with a mouse-adapted strain of T. gondii administered IM and oral administration with oocysts of H. hammondi were both unsuccessful (Lynch et al. 1993; Reddacliff et al. 1993b). Limitations to the development of an effective vaccine for T. gondii include the existence of multiple genetic lineages with variable strain virulence and the stage-specific expression of T. gondii proteins. Until advances are made in vaccine technology and delivery options for T. gondii vaccination, the options for prevention of toxoplasmosis in Australian mammals are limited.8.
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