References

Alpern JD, Bahr NC, Vazquez-Benitez G et al (2016) Diagnostic delay and antibiotic overuse in acute pulmonary blastomycosis. OpenForumInfectDis 3:ofw078. https://doi.org/10.1093/ofid/ ofw078

Anderson JL, Dieckman JL, Reed KD, Meece JK (2014) Canine blastomycosis in Wisconsin: a survey of small-animal veterinary practices.

Anderson JL, Meece JK, Hall MC, Frost HM (2016) Evidence of delayed dissemination or re-infection with Blastomyces in two immunocompetent hosts. Med Mycol Case Rep 13: 9-11. https://doi.org/10.10167j.mmcr.2016.09.002

Arceneaux KA, Taboada J, Hosgood G (1998) Blastomycosis in dogs: 115 cases (1980-1995). J Am Vet Med Assoc 213:658-664

Archer JR, Trainer DO, Schell RF (1987) Epidemiologic study of canine blastomycosis in Wisconsin. J Am Vet Med Assoc 190:1292-1295

Armstrong CW, Jenkins SR, Kaufman L et al (1987) Common-source outbreak of blastomycosis in hunters and their dogs. J Infect Dis 155:568-570

Azar MM, Assi R, Relich RF et al (2015) Blastomycosis in Indiana: clinical and epidemiologic patterns of disease gleaned from a multicenter retrospective study. Chest 148:1276-1284. https://doi.org/10.1378/chest.15-0289

Babady NE, Buckwalter SP, Hall L et al (2011) Detection of Blastomyces dermatitidis and Histoplasma capsulatum from culture isolates and clinical specimens by use of real-time PCR. J Clin Microbiol 49:3204-3208. https://doi.org/10.1128/JCM.00673-11

Bakleh M, Aksamit AJ, Tleyjeh IM, Marshall WF (2005) Successful treatment of cerebral blasto­mycosis with voriconazole. Clin Infect Dis 40:e69-e71. https://doi.org/10.1086/429319

Bariola JR, Perry P, Pappas PG et al (2010) Blastomycosis of the central nervous system: a multicenter review of diagnosis and treatment in the modern era. Clin Infect Dis 50:797-804. https://doi.org/10.1086/650579

Baumgardner DJ, Buggy BP, Mattson BJ et al (1992) Epidemiology of blastomycosis in a region of high endemicity in north central Wisconsin.

Baumgardner DJ, Burdick JS (1991) An outbreak of human and canine blastomycosis. Rev Infect Dis 13:898-905

Baumgardner DJ, Paretsky DP, Yopp AC (1995) The epidemiology of blastomycosis in dogs: north central Wisconsin, USA. J Med Vet Mycol 33:171-176

Bednarczyk JM, Kethireddy S, White CW et al (2015) Extracorporeal membrane oxygenation for blastomycosis related acute respiratory distress syndrome: a case series. Can J Anaesth 62: 807-815

Blondin N, Baumgardner DJ, Moore GE, Glickman LT (2007) Blastomycosis in indoor cats: suburban Chicago, Illinois, USA. Mycopathologia 163:59-66. https://doi.org/10.1007/ s11046-006-0090-1

Bloom JD, Hamor RE, Gerding PA (1996) Ocular blastomycosis in dogs: 73 cases, 108 eyes (1985-1993). J Am Vet Med Assoc 209:1271-1274

Borgia SM, Fuller JD, Sarabia A, El-Helou P (2006) Cerebral blastomycosis: a case series incorporating voriconazole in the treatment regimen. Med Mycol 44:659-664. https://doi.org/ 10.1080/13693780600803870

Bradsher RW (2014a) The endemic mimic: blastomycosis an illness often misdiagnosed. Trans Am Clin Climatol Assoc 125:188-202

Bradsher RW (2014b) Blastomycosis. In: Bennett JE, Dolin R, Blaser MJ (eds) Mandell, Douglas, and Bennett's principles and practice of infectious diseases, 8th edn. Elsevier, Amsterdam, pp 2963-2973

Broc R, Haddad N (1952) Tumeur bronchique a Scopulariopsis americana determination precoce d'une maladie de Gilchrist. Bull Mem Soc Med Hop Paris 68:678-682

Brooks DE, Legendre AM, Gum GG et al (1992) The treatment of canine ocular blastomycosis with systemically administered itraconazole. Prog Vet Comp Ophthalmol 4:263-268

Brown EM, McTaggart LR, Zhang SX et al (2013) Phylogenetic analysis reveals a cryptic species Blastomyces gilchristii, sp. nov. within the human pathogenic fungus Blastomyces dermatitidis. PLoS One 8:e59237

Bush JW, Wuerz T, Embil JM et al (2013) Outcomes of persons with blastomycosis involving the central nervous system.

Carman WF, Frean JA, Crewe-Brown HH et al (1989) Blastomycosis in Africa. A review of known cases diagnosed between 1951 and 1987. Mycopathologia 107:25-32

Cates MB, Kaufman L, Grabau JH et al (1986) Blastomycosis in an Atlantic bottlenose dolphin. J AmVetMedAssoc 189:1148-1150

Chapman SW, Dismukes WE, Proia LA et al (2008) Clinical practice guidelines for the manage­ment of blastomycosis: 2008 update by the Infectious Diseases Society of America. Clin Infect Dis 46:1801-1812

Connolly P, Hage CA, Bariola JR et al (2012) Blastomyces dermatitidis antigen detection by quantitative enzyme immunoassay. Clin Vaccine Immunol 19:53-56. https://doi.org/10.1128/ CVI.05248-11

Crews LJ, Feeney DA, Jessen CR et al (2008a) Utility of diagnostic tests for and medical treatment of pulmonary blastomycosis in dogs: 125 cases (1989-2006). J Am Vet Med Assoc 232: 222-227. https://doi.org/10.2460/javma.232.2.222

Crews LJ, Feeney DA, Jessen CR, Newman AB (2008b) Radiographic findings in dogs with pulmonary blastomycosis: 125 cases (1989-2006). J Am Vet Med Assoc 232:215-221. https://doi.org/10.2460/javma.232.2.215

Dalton HJ, Hertzog JH, Hannan RL et al (1999) Extracorporeal membrane oxygenation for overwhelming Blastomyces dermatitidis pneumonia. Crit Care 3:91-94

Davies C, Troy G (1996) Deep mycotic infections in cats. J Am Anim Hosp Assoc 32:380-391. https://doi.org/10.5326/15473317-32-5-380

Davies JL, Epp T, Burgess HJ (2013) Prevalence and geographic distribution of canine and feline blastomycosis in the Canadian prairies. Can Vet J 54:753-760

Denton JF, Di Salvo AF, Hirsch ML et al (1967) Laboratory-acquired North American blasto­mycosis. JAMA 199:935. https://doi.org/10.1001/jama.1967.03120120123030

Dismukes WE, Bradsher RW, Cloud GC et al (1992) Itraconazole therapy for blastomycosis and histoplasmosis. NIAID Mycoses Study Group. Am J Med 93:489-497

Dukik K, Munoz JF, Jiang Y et al (2017) Novel taxa of thermally dimorphic systemic pathogens in the Ajellomycetaceae (Onygenales).

Dykstra JA, Rogers LL, Mansfield SA et al (2012) Fatal disseminated blastomycosis in a free- ranging American black bear (Ursus americanus). J Vet Diagn Investig 24:1125-1128. https:// doi.org/10.1177/1040638712461788

Finn MJ, Stiles J, Krohne SG (2007) Visual outcome in a group of dogs with ocular blastomycosis treated with systemic antifungals and systemic corticosteroids. Vet Ophthalmol 10:299-303. https://doi.org/10.1111/j.1463-5224.2007.00554.x

Foy DS, Trepanier LA, Kirsch EJ, Wheat LJ (2014) Serum and urine Blastomyces antigen concentrations as markers of clinical remission in dogs treated for systemic blastomycosis. J Vet Intern Med 28:305-310. https://doi.org/10.1111/jvim.12306

Frost HM, Novicki TJ (2015) Blastomyces antigen detection for the diagnosis and management of blastomycosis. J Clin Microbiol 53:02352-02315. https://doi.org/10.1128/JCM.02352-15

Gilchrist TC (1894) Protozoan dermatitis. J Cutan Gen Dis 12:496-499

Gilchrist TC, Stokes WR (1898) A case of pseudo-lupus vulgaris caused by a blastomyces. J Exp Med 3:53-78

Gonzalez GM, Fothergill AW, Sutton DA et al (2005) In vitro activities of new and established triazoles against opportunistic filamentous and dimorphic fungi. Med Mycol 43:281-284. https://doi.org/10.1080/13693780500088416

Gray NA, Baddour LM (2002) Cutaneous inoculation blastomycosis. Clin Infect Dis 34:E44-E49. https://doi.org/10.1086/339957

Guarner J, Brandt ME (2011) Histopathologic diagnosis of fungal infections in the 21st century. Clin Microbiol Rev 24:247-280. https://doi.org/10.1128/CMR.00053-10

Harris JR, Blaney DD, Lindsley MD et al (2011) Blastomycosis in man after kinkajou bite. Emerg InfectDis 17:268-270. https://doi.org/10.3201/eid1702.101046

Herrmann JA, Kostiuk SL, Dworkin MS, Johnson YJ (2011) Temporal and spatial distribution of blastomycosis cases among humans and dogs in Illinois (2001-2007). J Am Vet Med Assoc 239:335-343. https://doi.org/10.2460/javma.239.3.335

Hough CL (2014) Steroids for acute respiratory distress syndrome? Clin Chest Med 35:781-795 Houseright RA, Webb JL, Claus KN (2015) Pathology in practice.

Imai DM, McGreevey N, Anderson JL, Meece JK (2014) Disseminated Blastomyces dermatitidis, genetic group 2, infection in an alpaca ( Vicugnapacos). J Vet Diagn Invest 26:442-447. https:// doi.org/10.1177/1040638714523773

Kaufman L, Standard PG, Weeks RJ, Padhye AA (1983) Detection of two Blastomyces dermatitidis serotypes by exoantigen analysis. J Clin Microbiol 18:110-114

Kingston M, El-Mishad MM, Ali MA (1980) Blastomycosis in Saudi Arabia. Am J Trop Med Hyg 29:464-466

Klein BS, Vergeront JM, Weeks RJ et al (1986) Isolation of Blastomyces dermatitidis in soil associated with a large outbreak of blastomycosis in Wisconsin. N Engl J Med 314:529-534

Kralt D, Light B, Cheang M et al (2009) Clinical characteristics and outcomes in patients with pulmonary blastomycosis. Mycopathologia 167:115-124

Kuttin ES, Beemer AM, Levij J et al (1978) Occurrence of Blastomyces dermatitidis in Israel. First autochthonous Middle Eastern case. Am J Trop Med Hyg 27:1203-1205

Lahm T, Neese S, Thornburg AT et al (2008) Corticosteroids for blastomycosis-induced ARDS: a report of two patients and review of the literature. Chest 133:1478-1480

Langlois DK, Pelosi A, Kruger JM (2013) Successful treatment of intracardiac and intraocular blastomycosis in a dog with combination azole therapy. J Am Anim Hosp Assoc 49:273-280. https://doi.org/10.5326/JAAHA-MS-5874

Legendre AM (2012) Blastomycosis. In: Greene CE (ed) Infectious diseases of the dog and cat, 4th edn. Elsevier, Amsterdam, pp 606-614

Legendre AM, Rohrbach BW, Toal RL et al (1996) Treatment of blastomycosis with itraconazole in 112 dogs. J Vet Intern Med 10:365-371

Lemos LB, Baliga M, Guo M (2002) Blastomycosis: the great pretender can also be an opportunist. Initial clinical diagnosis and underlying diseases in 123 patients. Ann Diagn Pathol 6:194-203

Lemos LB, Baliga M, Guo M (2001) Acute respiratory distress syndrome and blastomycosis: presentation of nine cases and review of the literature.

Li RK, Ciblak MA, Nordoff N et al (2000) In vitro activities of voriconazole, itraconazole, and amphotericin B against Blastomyces dermatitidis, Coccidioides immitis, and Histoplasma capsulatum. Antimicrob Agents Chemother 44(6):1734. https://doi.org/10.1128/AAC.44.6. 1734-1736.2000

Limper AH, Knox KS, Sarosi GA et al (2011) An official American Thoracic Society statement: treatment of fungal infections in adult pulmonary and critical care patients. Am J Respir Crit CareMed 183:96-128

Lloret A, Hartmann K, Pennisi MG et al (2013) Rare systemic mycoses in cats: blastomycosis, histoplasmosis and coccidioidomycosis: ABCD guidelines on prevention and management. J Feline Med Surg 15(7):624. https://doi.org/10.1177/1098612X13489226

Lombardi G, Padhye AA, Ajello L (1988) In vitro conversion of African isolates of Blastomyces dermatitidis to their yeast form. Mycoses 31:447-450

Lopez R, Mason JO, Parker JS, Pappas PG (1994) Intraocular blastomycosis: case report and review. Clin Infect Dis 18:805-807

Martynowicz MA, Prakash UBS (2002) Pulmonary blastomycosis: an appraisal of diagnostic techniques. Chest 121:768-773. https://doi.org/10.1378/chest.12L3.768

Mazepa ASW, Trepanier LA, Foy DS (2011) Retrospective comparison of the efficacy of flucon­azole or itraconazole for the treatment of systemic blastomycosis in dogs. J Vet Intern Med 25: 440-445. https://doi.org/10.1111/j.1939-1676.2011.0710.x

Meece JK, Anderson JL, Fisher MC et al (2011) Population genetic structure of clinical and environmental isolates of Blastomyces dermatitidis, based on 27 polymorphic microsatellite markers. Appl Environ Microbiol 77:5123-5131. https://doi.org/10.1128/AEM.00258-11

Meece JK, Anderson JL, Gruszka S et al (2013) Variation in clinical phenotype of human infection among genetic groups of Blastomyces dermatitidis. J Infect Dis 207:814-822. https://doi.org/ 10.1093/infdis/jis756

Meyer K (1912) Blastomycosis in dogs. Proc Path Soc Philadelphia 15:10

Meyer KC, McManus EJ, Maki DG (1993) Overwhelming pulmonary blastomycosis associated with the adult respiratory distress syndrome. N Engl J Med 329:1231-1236

Nemeth NM, Campbell GD, Oesterle PT et al (2016) Red fox as sentinel for Blastomyces dermatitidis, Ontario, Canada. Emerg Infect Dis 22(7):1275. https://doi.org/10.3201/eid2207. 151789

Oppenheimer M, Embil JM, Black B et al (2007) Blastomycosis of bones and joints. South Med J 100:570-578. https://doi.org/10.1097/SMJ.0b013e3180487a92

Pappas PG, Bradsher RW, Kauffman CA et al (1997) Treatment of blastomycosis with higher doses of fluconazole. The National Institute of Allergy and Infectious Diseases Mycoses Study Group. Clin Infect Dis 25:200-205

Pappas PG, Threlkeld MG, Bedsole GD et al (1993) Blastomycosis in immunocompromised patients. Medicine (Baltimore) 72:311-325

Patel AJ, Gattuso P, Reddy VB (2010) Diagnosis of blastomycosis in surgical pathology and cytopathology: correlation with microbiologic culture. Am J Surg Pathol 34:256-261. https:// doi.org/10.1097/PAS.0b013e3181ca48a5

Patel RG, Patel B, Petrini MF et al (1999) Clinical presentation, radiographic findings, and diagnostic methods of pulmonary blastomycosis: a review of 100 consecutive cases. South Med J 92:289-295

Perfect JR, Savani DV, Durack DT (1986) Comparison of itraconazole and fluconazole in treatment of cryptococcal meningitis and candida pyelonephritis in rabbits. Antimicrob Agents Chemother 29:579-583

Plamondon M, Lamontagne F, Allard C, Pepin J (2010) Corticosteroids as adjunctive therapy in severe blastomycosis-induced acute respiratory distress syndrome in an immunosuppressed patient. Clin Infect Dis 51:e1-e3

Randhawa HS, Khan ZU, Gaur SN (1983) Blastomyces dermatitidis in India: first report of its isolation from clinical material. Sabouraudia 21:215-221

Resch M, Kurz K, Schneider-Brachert W et al (2009) Extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) in fulminant blastomycosis in Germany. BMJ Case Rep 2009:bcr0720080392. https://doi.org/10.1136/bcr.07.2008.0392

Restrepo A, Baumgardner DJ, Bagagli E et al (2000) Clues to the presence of pathogenic fungi in certain environments. Med Mycol 38(Suppl 1):67-77

Richer SM, Smedema ML, Durkin MM et al (2014) Development of a highly sensitive and specific blastomycosis antibody enzyme immunoassay using Blastomyces dermatitidis surface protein BAD-1. Clin Vaccine Immunol 21:143-146. https://doi.org/10.1128/CVI.00597-13

Rosser MF, Lindemann DM, Barger AM et al (2016) Systemic blastomycosis in a captive red ruffed lemur (Varecia rubra). J Zoo Wildl Med 47:912-916. https://doi.org/10.1638/2016-0019.1

Rudmann DG, Coolman BR, Perez CM, Glickman LT (1992) Evaluation of risk factors for blastomycosis in dogs: 857 cases (1980-1990). J Am VetMed Assoc 201:1754-1759

Saccente M, Abernathy RS, Pappas PG et al (1998) Vertebral blastomycosis with paravertebral abscess: report of eight cases and review of the literature. Clin Infect Dis 26:413-418

Saccente M, Woods GL (2010) Clinical and laboratory update on blastomycosis. Clin Microbiol Rev 23:367-381

Sarosi GA, Eckman MR, Davies SF, Laskey WK (1979) Canine blastomycosis as a harbinger of human disease. Ann Intern Med 91:733. https://doi.org/10.7326/0003-4819-91-5-733

Sarosi GA, Hammerman KJ, Tosh FE, Kronenberg RS (1974) Clinical features of acute pulmonary blastomycosis. N Engl J Med 290:540-543. https://doi.org/10.1056/NEJM197403072901004

Savani DV, Perfect JR, Cobo LM, Durack DT (1987) Penetration of new azole compounds into the eye and efficacy in experimental Candida endophthalmitis. Antimicrob Agents Chemother 31:6-10

Schmiedt C, Kellum H, Legendre AM et al (2015) Cardiovascular involvement in 8 dogs with blastomyces dermatitidis infection. J Vet Intern Med 20:1351-1354. https://doi.org/10.1892/ 0891-6640(2006)20[1351:CIIDWB]2.0.C0;2

Schwartz IS, Embil JM, Sharma A et al (2016) Management and outcomes of acute respiratory distress syndrome caused by blastomycosis: a retrospective case series. Medicine (Baltimore) 95:e3538. https://doi.org/10.1097/MD.0000000000003538

Smith JA, Gauthier G (2015) New developments in blastomycosis. Semin Respir Crit Care Med 36: 715-728. https://doi.org/10.1055/s-0035-1562898

Smith JA, Kauffman CA (2009) Endemic fungal infections in patients receiving tumour necrosis factor-alpha inhibitor therapy. Drugs 69:1403-1415. https://doi.org/10.2165/00003495- 200969110-00001

Spector D, Legendre AM, Wheat J et al (2008) Antigen and antibody testing for the diagnosis of blastomycosis in dogs. J Vet Intern Med 22:839-843. https://doi.org/10.1111Zj.1939-1676. 2008.0107.x

Stewart AJ, Cuming RS (2015) Update on fungal respiratory disease in horses. Vet Clin North Am Equine Pract 31:43-62. https://doi.org/10.1016/j.cveq.2014.11.005

Storms TN, Clyde VL, Munson L, Ramsay EC (2003) Blastomycosis in nondomestic felids. J Zoo Wildl Med 34:231-238. https://doi.org/10.1638/1042-7260(2003)034[0231:BINF]2.0.C0;2

Sykes JE, Merkel LK (2014) Blastomycosis. In: Sykes JE (ed) Canine and feline infectious diseases. Elsevier, St. Louis, pp 574-586

Ta M, Flowers SA, Rogers PD (2009) The role of voriconazole in the treatment of central nervous system blastomycosis. Ann Pharmacother 43:1696-1700. https://doi.org/10.1345/aph.1M010

Vandepitte J, Gatti F (1972) A case of North American blastomycosis in Africa. Its existence in Republic of Zaire. Ann la Societe belge medecine Trop 52:467-479

Vasquez JE, Mehta JB, Agrawal R, Sarubbi FA (1998) Blastomycosis in northeast Tennessee. Chest 114:436-443

Wilkinson LM, Wallace JM, Cline JM (1999) Disseminated blastomycosis in a rhesus monkey (Macaca mulatto). Vet Pathol 36:460-462. https://doi.org/10.1354/vp.36-5-460

Williams JE, Moser SA (1987) Chronic murine pulmonary blastomycosis induced by intra- tracheally inoculated Blastomyces dermatitidis conidia. Am Rev Respir Dis 135:17-25. https://doi.org/10.1164/arrd.1987.135.1.17

Wilson JH, Olson EJ, Haugen EW et al (2006) Systemic blastomycosis in a horse. J Vet Diagn Investig 18:615-619. https://doi.org/10.1177/104063870601800619

Wuthrich M, Filutowicz HI, Klein BS (2000) Mutation of the WI-1 gene yields an attenuated blastomyces dermatitidis strain that induces host resistance. J Clin Investig 106:1381-1389. https://doi.org/10.1172/JCI11037

Wuthrich M, Krajaejun T, Shearn-Bochsler V et al (2011) Safety, tolerability, and immunogenicity of a recombinant, genetically engineered, live-attenuated vaccine against canine blastomycosis. Clin Vaccine Immunol 18:783-789. https://doi.org/10.1128/CVI.00560-10

Zwick LS, Briggs MB, Tunev SS et al (2000) Disseminated blastomycosis in two California sea lions (Zalophus californianus). J Zoo Wildl Med 31:211-214. https://doi.org/10.1638/1042- 7260(2000)031[0211:DBITCS]2.0.C0;2