References
Allenspach K, Bergman P, Sauter S, Grone A, Doherr M, Gaschen F (2006) P-glycoprotein expression in lamina propria lymphocytes of duodenal biopsy samples in dogs with chronic idiopathic enteropathies.
Journal of Comparative Pathology 134, 1-7. doi:10.1016/j. jcpa.2005.06.003Alvinerie M, Escudero E, Sutra J-F, Eeckhoutte C, Galtier P (1998) 'The pharmacokinetics of moxidectin after oral and subcutaneous administration to sheep. Veterinary Research 29, 113-118.
Baggot JD (1992) Bioavailability and bioequivalence of veterinary drug dosage forms, with particular reference to horses: an overview. Journal of Veterinary Pharmacology and Therapeutics 15, 160-173. doi:10.1111/j.1365-2885.1992.tb01003.x
Bains J, Carver S, Hua S (2022) Pathophysiological and pharmaceutical considerations for enhancing the control of Sarcoptes scabiei in wombats through improved transdermal drug delivery. Frontiers in Veterinary Science 9, 944578.
Barbosa L, Johnson SP, Papich MG, Gulland F (2015) Pharmacokinetics of single dose orally administered ciprofloxacin in California sea lions (Zalophus californianus). Journal of Zoo and Wildlife Medicine 46, 266-272. doi:10.1638/2014-0159R.1
Bayat S, Geiser F, Kristiansen P, Wilson SC (2014) Organic contaminants in bats: trends and new issues. Environment International 63, 40-52. doi:10.1016/j.envint.2013.10.009
Bermingham EC, Papich MG, Vivrette SL (2000) Pharmacokinetics of enrofloxacin administered intravenously and orally to foals. American Journal of Veterinary Research 61, 706-709. doi:10.2460/ ajvr.2000.61.706
Best SM (1973) Some organochlorine pesticide residues in wildlife of the Northern Territory, Australia, 1970-71. Australian Journal of Biological Sciences 26, 1161-1170. doi:10.1071/BI9731161
Bidgood TL, Papich MG (2005) Plasma and interstitial fluid pharmacokinetics of enrofloxacin, its metabolite ciprofloxacin, and marbo- floxacin after oral administration and a constant rate intravenous infusion in dogs.
Journal of Veterinary Pharmacology and Therapeutics 28, 329-341. doi:10.1111/j.1365-2885.2005.00664.xBlack LA, McLachlan AJ, Griffith JE, Higgins DP, Gillett A, Krocken- berger MB, Govendir M (2013) Pharmacokinetics of chloramphenicol following administration of intravenous and subcutaneous chloramphenicol succinate, and subcutaneous chloramphenicol, to koalas (Phascolarctos cinereus). Journal of Veterinary Pharmacology and Therapeutics 36, 478-485. doi:10.1111/jvp.12024
Black LA, Krockenberger MB, Kimble B, Govendir M (2014a) Pharmacokinetics of fluconazole following intravenous and oral administration to koalas (Phascolarctos cinereus). Journal of Veterinary Pharmacology and Therapeutics 37, 90-98. doi:10.1111/jvp.12072
Black LA, Landersdorfer C, Bulitta J, Griffith JE, Govendir M (2014b) Evaluation of enrofloxacin use in koalas (Phascolarctos cinereus) via population pharmacokinetics and Monte Carlo simulation. Journal of Veterinary Pharmacology and Therapeutics 37, 301-311. doi:10.1111/jvp.12091
Black LA, Higgins DP, Govendir M (2015) In vitro activities of chloramphenicol, florfenicol and enrofloxacin against Chlamydia pecorum isolated from koalas (Phascolarctos cinereus). Australian Veterinary Journal 93, 420-423. doi:10.1111/avj.12364
Bolton RM, Ahokas JT (1995) Detoxication in Australian marsupials: ecotoxicological implications. Australian Journal of Ecotoxicology 1, 85-98.
Boonstra JL, Barbosa L, Van Bonn WG, Johnson SP, Gulland FM, Cox SK, Martin-Jimenez T (2015) Pharmacokinetics of tramadol hydrochloride and its metabolite of tramadol hydrochloride and its metabolite 0-desmethylramadol following a single, orally administered dose in California sea lions (Zalophus californianus). Journal of Zoo and Wildlife Medicine 46, 476-481. doi:10.1638/2014-0183.1
Booth R, Nyari S (2020) Clinical comparison of five anti-chlamydial antibiotics in koalas (Phascolarctos cinereus). PLoS ONE 15, e0236758. doi:10.1371/journal.pone.0236758
Boyle RR, McLean S (2004) Constraint of feeding by chronic ingestion of 1, 8-cineole in the brushtail possum (Trichosurus vulpecula).
Journal of Chemical Ecology 30, 757-775. doi:10.1023/B:J0EC.00000 28430.92739.83Boyle R, McLean S, Foley W, Davies N, Peacock E, Moore B (2001) Metabolites of dietary 1,8-cineole in the male koala (Phascorlactos cinereus). Comparative Biochemistry and Physiology. Part C: Pharmacology, Toxicology & Endocrinology 129, 385-395. doi:10.1016/ S1532-0456(01)00214-9
Bradshaw SD, Morris KD, Bradshaw FJ (2001) Water and electrolyte homeostasis and kidney function of desert-dwelling marsupials wallabies in Western Australia. Journal of Comparative Physiology. B: Biochemical, Systemic, and Environmental Physiology 171, 23-32. doi:10.1007/s003600000144
Broome RL, Brooks DL, Babish JG, Copeland DD, Conzelman GM (1991) Pharmacokinetic properties of enrofloxacin in rabbits. American Journal of Veterinary Research 52, 1835-1841.
Brown AS, Wood AD, Dickens RK (1984) Dirty tail and other chlamydial diseases in koalas. In Control and Therapy Series No. 1792. Post Graduate Foundation in Veterinary Science, University of Sydney.
Budd C, Flanagan C, Gillett A, Hanger J, Loader JJ, Govendir M (2017) Assessment of florfenicol as a possible treatment for chlamydiosis in koalas (Phascolarctos cinereus). Australian Veterinary Journal 95, 343-349. doi:10.1111/avj.12617
Busch U, Schmid J, Heinzel G, Schmaus H, Baierl J, Huber C, Roth W (1998) Pharmacokinetics of meloxicam in animals and the relevance to humans. Drug Metabolism and Disposition: The Biological Fate of Chemicals 26, 576-584.
Chen C-J, Gillett A, Booth R, Kimble B, Govendir M (2022) Pharmacokinetic profile of doxycycline in koala plasma after weekly subcutaneous injections for the treatment of chlamydiosis. Animals 12, 250.
Chen C-J, Casteriano A, Green AC, Govendir M (2023) A retrospective study on antibacterial treatments for koalas infected with Chlamydia pecorum. Scientific Reports 13, 12670.
Clark DR (1988) How sensitive are bats to insecticides? Wildlife Society Bulletin 16, 399-403.
Clark C, Milton J, Thomas J, Goolsby W (1982) Plasma concentrations of chloramphenicol in marsupials: wallabies (Wallabia eugenii) and opossums (Didelphis marsupialis).
The Journal of Zoo Animal Medicine 13, 121-123. doi:10.2307/20094593Cork SJ, Warner ACI (1983) The passage of digesta markers through the gut of a folivorous marsupial, the koala (Phascolarctos cinereus). Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology 152, 43-51. doi:10.1007/BF00689726
Cork SJ, Hume ID, Dawson TJ (1983) Digestion and metabolism of a natural foliar diet (Eucalyptus punctata) by an arboreal marsupial, the koala (Phascolarctos cinereus). Journal of Comparative Physiology. B: Biochemical, Systemic, and Environmental Physiology 153, 181-190. doi:10.1007/BF00689622
Court MH, Robbins AH, Whitford AM, Beck EV, Tseng FS, Reeder DM (2017) Pharmacokinetics of terbinafine in little brown myotis (Myotis lucifugus) infected with Pseudogymnoascus destructans. American Journal of Veterinary Research 78, 90-99. doi:10.2460/ ajvr.78.1.90
Cripps J, Beveridge I, Coulson G (2013) The efficacy of anthelmintic drugs against nematodes infecting free-ranging eastern grey kangaroos, Macropus giganteus. Journal of Wildlife Diseases 49, 535-544. doi:10.7589/2012-06-151
Dawson T, Denny M (1969) Seasonal variation in the plasma and the urine electrolyte concentration of the arid zone kangaroos Megaleia rufa and the Macropus robustus. Australian Journal of Zoology 17, 777-784. doi:10.1071/ZO9690777
Dawson T, Hulbert A (1969) Standard energy metabolism of marsupials. Nature 221, 383. doi:10.1038/221383a0
Dawson TJ, Hulbert AJ (1970) Standard metabolism, body temperature, and surface areas of Australian marsupials. The American Journal of Physiology 218, 1233-1238. doi:10.1152/ajplegacy.1970.218.4.1233
Death CE, Taggart DA, Williams DB, Milne R, Schultz DJ, Holyoake C, Warren KS (2011) Pharmacokinetics of moxidectin in the southern hairy-nosed wombat (Lasiorhinus latifrons). Journal of Wildlife Diseases 47, 643-649. doi:10.7589/0090-3558-47.3.643
Denny MJ, Dawson TJ (1977) Kidney structure and function of desert kangaroos.
Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology 42, 636-642. doi:10.1152/jappl.1977.42.4.636Di L (2014) The role of drug metabolizing enzymes in clearance. Expert Opinion on Drug Metabolism & Toxicology 10, 379-393. doi:10.1517 /17425255.2014.876006
Downey PM, Caraguel CG, Speight N, Fabijan J, Boardman WS (2020) Field immobilization using alfaxalone and alfaxalone-medetomidine in free-ranging koalas (Phascolarctos cinereus): a randomized comparative study. Veterinary Anaesthesia and Analgesia 47, 368-376.
Duggin G, Mudge G (1975) Renal tubular transport of paracetamol and its conjugates in the dog. British Journal of Pharmacology 54, 359-366.
Eason C, Wright G, Gooneratne R (1999) Pharmacokinetics of antipy- rine, warfarin and paracetamol in the brushtail possum. Journal of Applied Toxicology 19, 157-161. doi:10.1002/(SICI)1099-1263 (199905/06)19:33.0.CO;2-K
Eidels RR, Sparks DW, Whitaker JO, Sprague CA (2016) Sub-lethal effects of chlorpyrifos on big brown bats (Eptesicus fuscus). Archives of Environmental Contamination and Toxicology 71, 322-335. doi:10.1007/s00244-016-0307-3
El-Merhibi A, Ngo SNT, Jones BR, Milic NL, Stupans I, McKinnon RA (2007) Molecular insights into xenobiotic disposition in Australian marsupials. Australian Journal of Ecotoxicology 13, 53-64.
Fink-Gremmels J (2008) Implications of hepatic cytochrome P450- related biotransformation processes in veterinary sciences. European Journal of Pharmacology 585, 502-509. doi:10.1016/j. ejphar.2008.03.013
Foley WJ, Moore BD (2005) Plant secondary metabolites and vertebrate herbivores: from physiological regulation to ecosystem function. Current Opinion in Plant Biology 8, 430-435. doi:10.1016/j. pbi.2005.05.009
Freeland WJ, Janzen DH (1974) Strategies in herbivory by mammals: the role of plant secondary compounds. American Naturalist 108, 269-289. doi:10.1086/282907
Gandolf AR, Papich MG, Bringardner AB, Atkinson MW (2005) Pharmacokinetics after intravenous, subcutaneous, and oral administration of enrofloxacin to alpacas.
American Journal of Veterinary Research 66, 767-771. doi:10.2460/ajvr.2005.66.767Garcia-Parraga D, Gilabert JA, Valls M, Ros-Rodriguez JM, Alvaro T, Rojo-Solis C, Encinas T (2010) Pharmacokinetics of cefovecin (Convenia™) after intramuscular administration to dolphins (Tursiops truncatus) and sea lion (Otaria flavescens). In Proceedings of 41st Annual Conference of International Association of Aquatic Animal Medicine, pp. 42-43. Vancouver, British Columbia.
Garcia-Parraga D, Gilabert J, Garcia-Pena F, Alvaro T, Ros-Rodriguez J, Valls M, Encinas T (2016) Long-lasting concentrations of cefo- vecin after subcutaneous and intramuscular administration to Patagonian sea lions (Otaria flavescens). Veterinary Journal (London, England) 208, 65-69. doi:10.1016/j.tvjl.2015.09.015
Gharibi S (2018) Study into selected antimicrobial drugs for koalas (Phascolarctos cinereus), incorporating consideration of koalas’ endogenous plasma and serum antibacterial activity. PhD thesis. The University of Sydney, Australia. http://hdl.handle.net/2123/18012
Gharibi S, Kimble B, Vogelnest L, Barnes J, Stadler CK, Govendir M (2017) Pharmacokinetics of posaconazole in koalas (Phascolarc- tos cinereus) after intravenous and oral administration. Journal of Veterinary Pharmacology and Therapeutics doi:10.1111/ jvp.12407.
Gharibi S, Vogelnest L, Govendir M (2019) In vitro binding of cefo- vecin to plasma proteins in Australian marsupials and plasma concentrations of cefovecin following single subcutaneous administration to koalas (Phascolarctos cinereus). Australian Veterinary Journal 97, 75-80.
Goodnight AL, Cox S (2018) Pharmacokinetics of meloxicam following a single oral dose in Malayan flying foxes (Pteropus vampyrus). Journal of Zoo and Wildlife Medicine 49, 307-314. doi:10.1638/2017-0067.1
Govendir M (2018) Review of some pharmacokinetics and pharmacodynamic properties of anti-infective medicines administered to the koala (Phascolarctos cinereus). Journal of Veterinary Pharmacology and Therapeutics 41, 1-10. doi:10.1111/jvp.12435
Govendir M, Hanger J, Loader JJ, Kimble B, Griffith JE, Black LA, Krockenberger MB, Higgins DP (2012) Plasma concentrations of chloramphenicol after subcutaneous administration to koalas (Phascolarctos cinereus) with chlamydiosis. Journal of Veterinary Pharmacology and Therapeutics 35, 147-154. doi:10.1111/j.1365- 2885.2011.01307.x
Govendir M, Black LA, Jobbins S, Kimble B, Malik R, Krockenberger MB (2016) Some pharmacokinetic indices of oral fluconazole administration to koalas (Phascolarctos cinereus) infected with cryptococcosis. Journal of Veterinary Pharmacology and Therapeutics 39, 412-415. doi:10.1111/jvp.12285
Govendir M, Vogelnest L, Shapiro AJ, Marschner C, Kimble B (2024) Pharmacokinetic profile of oral and subcutaneous administration of paracetamol in the koala (Phascolarctos cinereus) and prediction of its analgesic efficacy. PLoS ONE 19, e0300703. doi.10.1371/journal. pone.0300703
Griffith JE (2010) Studies into the diagnosis, treatment and management of chlamydiosis. PhD thesis. The University of Sydney, Australia..
Griffith JE, Higgins DP, Li KM, Krockenberger MB, Govendir M (2010) Absorption of enrofloxacin and marbofloxacin after oral and subcutaneous administration in diseased koalas (Phascolarctos cinereus). Journal of Veterinary Pharmacology and Therapeutics 33, 595-604. doi:10.1111/j.1365-2885.2010.01169.x
Hunter RP, Isaza R (2008) Concepts and issues with interspecies scaling in zoological pharmacology. Journal of Zoo and Wildlife Medicine 39, 517-526. doi:10.1638/2008-0041.1
Johnson R, Hemsley S (2008) Gliders and possums. In Medicine of Australian Mammals. (Eds L Vogelnest and R Woods) pp. 395-437. CSIRO Publishing, Melbourne.
Kendall J, Papich MG (2015) Posaconazole pharmacokinetics after administration of an intravenous solution, oral suspension, and delayed-release tablet to dogs. American Journal of Veterinary Research 76, 454-459. doi:10.2460/ajvr.76.5.454
Kimble B (2015) Pharmacokinetic aspects of meloxicam in koalas: including its hepatic microsomal metabolism compared with other selected species. PhD thesis. The University of Sydney, Australia..
Kimble B, Black LA, Li KM, Valchev P, Gilchrist S, Gillett A, Higgins DP, Krockenberger MB, Govendir M (2013a) Pharmacokinetics of meloxicam in koalas (Phascolartos cinereus) after intravenous, subcutaneous and oral administration. Journal of Veterinary Pharmacology and Therapeutics 36, 486-493. doi:10.HH/jvp.12038
Kimble B, Li KM, Govendir M (2013b) Quantitation of meloxicam in the plasma of koalas (Phascolarctos cinereus) by improved high performance liquid chromatography. Journal of Veterinary Science (Suwon-si, Korea) 14, 7-14. doi:10.4142/jvs.2013.14.1.7
Kimble B, Li KM, Valtchev P, Higgins DP, Krockenberger MB, Govendir M (2014) In vitro metabolism of meloxicam in koalas (Phascolarctos cinereus), brushtail possums (Trichosurus vulpecula), ringtail possums (Pseudocheirus peregrinus), rats and dogs. Comparative Biochemistry and Physiology. Part C: Pharmacology, Toxicology & Endocrinology 161, 7-14. doi:10.1016/j.cbpc.2013.12.002
Kimble B, Vogelnest L, Gharibi S, Izes AM, Govendir M (2020) Pharmacokinetic profile of amoxicillin and its glucuronide-like metabolite when administered subcutaneously to koalas (Phascolarctos cinereus). Journal of Veterinary Pharmacology and Therapeutics 43, 115-122.
Kimble B, Vogelnest L, Valtchev P, Govendir M (2021) Pharmacokinetic profile of injectable tramadol in the koala (Phascolarctos cinereus) and prediction of its analgesic efficacy. PLoS One 16, e0247546.
King D, Oliver A, Mead R (1978) The adaptation of some Western Australian mammals to food plants containing fluoroacetate. Australian Journal of Zoology 26, 699-712. doi:10.1071/ZO9780699
Kirkwood J, Gulland F, Needham J, Vogler M (1988) Pharmacokinetics of oxytetracycline in clinical cases in the red-necked wallaby (Macropus rufogriseus). Research in Veterinary Science 44, 335-337.
Knoll U, Glunder G, Kietzmann M (1999) Comparative study of the plasma pharmacokinetics and tissue concentrations of danofloxa- cin and enrofloxacin in broiler chickens. Journal of Veterinary Pharmacology and Therapeutics 22, 239-246. doi:10.1046/j.1365- 2885.1999.00217.x
Kohlhoff SA, Hammerschlag MR (2015) Treatment of chlamydial infections: 2014 update. Expert Opinion on Pharmacotherapy 16, 205-212. doi:10.1517/14656566.2015.999041
Lanusse C, Lifschitz A, Virkel G, Alvarez L, Sanchez S, Sutra J, Galtier P, Alvinerie M (1997) Comparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle. Journal of Veterinary Pharmacology and Therapeutics 20, 91-99. doi:10.1046/ j.1365-2885.1997.00825.x
Lautzenhiser SJ, Fialkowski JP, Bjorling D, Rosin E (2001) In vitro antibacterial activity of enrofloxacin and ciprofloxacin in combination against Escherichia coli and staphylococcal clinical isolates from dogs. Research in Veterinary Science 70, 239-241. doi:10.1053/ rvsc.2001.0466
Le-Bert CR (2023) Anaesthesia physiology of bottlenose dolphins (Tursiops truncatus) and California sea lions (Zalophus califor- nianus). PhD thesis. University of Florida, USA. https://original- ufdc.uflib.ufl.edu/UFE0060330/00001/citation
Liapis P, Pass GJ, McKinnon RA, Stupans I (2000) Characterisation of tolbutamide hydroxylase activity in the common brushtail possum (Trichosurus vulpecula) and koala (Pharscolarctos cinereus): inhibition by the Eucalyptus terpene 1,8-cineole. Comparative Biochemistry and Physiology. Part C: Pharmacology, Toxicology & Endocrinology 127, 351-357. doi:10.1016/S0742-8413(00)00163-8
Lillo JG (2020) Study into the intrinsic clearance of carprofen in selected species - with emphasis in the koala (Phascolarctos cinereus). MPhil thesis. The University of Sydney, Australia. https://hdl.handle. net/2123/23997
Lin JH, Lu AY (1997) Role of pharmacokinetics and metabolism in drug discovery and development. Pharmacological Reviews 49, 403-449.
Lindup WE, Orme MC (1981) Clinical pharmacology: plasma protein binding of drugs. British Medical Journal 282, 212-214. doi:10.1136/ bmj.282.6259.212
Martignoni M, Groothuis GMM, de Kanter R (2006) Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opinion on Drug Metabolism & Toxicology 2, 875-894. doi:10.1517/17425255.2.6.875
Martinez MN (2005) Interspecies differences in physiology and pharmacology: extrapolating preclinical data to human populations. In Preclinical Drug Development. (Eds M Rogge and D Taft) pp. 11-66. Marcel Dekker, New York.
McDowell A, McLeod BJ (2007) Physiology and pharmacology of the brushtail possum gastrointestinal tract: relationship to the human gastrointestinal tract. Advanced Drug Delivery Reviews 59, 11211132. doi:10.1016/j.addr.2007.06.012
McLean SR, Foley WF (1997) Metabolism of Eucalyptus terpenes by herbivorous marsupials. Drug Metabolism Reviews 29, 213-218. doi:10.3109/03602539709037582
McLean S, Brandon S, Davies NW, Boyle R, Foley WJ, Moore B, Pass GJ (2003) Glucuronuria in the koala. Journal of Chemical Ecology 29, 1465-1477. doi:10.1023/A:1024273722192
McLelland DJ, Rich BG, Holz PH (2009) 'The pharmacokinetics of single dose intramuscular amoxicillin trihydrate in tammar wallabies (Macropus eugenii). Journal of Zoo and Wildlife Medicine 40, 113-116. doi:10.1638/2008-0104.1
McLelland DJ, Barker IK, Crawshaw G, Hinds LA, Spilsbury L, Johnson R (2011) Single-dose pharmacokinetics of oxytetracycline and penicillin G in tammar wallabies (Macropus eugenii). Journal of Veterinary Pharmacology and Therapeutics 34, 160-167. doi:10.1111/ j.1365-2885.2010.01216.x
Meegan J, Collard WT, Grover GS, Pussini N, Van Bonn WG, Gulland FM (2013) Pharmacokinetics of ceftiofur crystalline-free acid (Excede sterile suspension®) administered via intramuscular injection in wild California sea lions (Zalophus californianus). Journal of Zoo and Wildlife Medicine 44, 714-720. doi:10.1638/2013-0001R.1
Milligan T, Morris H, Hammond P, Price C (1994) Studies on paracetamol binding to serum proteins. Annals of Clinical Biochemistry 31, 492-496.
Mounsey K, Harvey RJ, Wilkinson V, Takano K, Old J, Stannard H, Wicker L, Phalen D, Carver S (2022) Drug dose and animal welfare: important considerations in the treatment of wildlife. Parasitology Research 121, 1065-1071.
Ngo S, McKinnon R, Stupans I (2006) Cloning and expression of koala (Phascolarctos cinereus) liver cytochrome P450 CYP4A15. Gene 376, 123-132. doi:10.1016/j.gene.2006.02.020
Nielsen P, Gyrd-Hansen N (1997) Bioavailability of enrofloxacin after oral administration to fed and fasted pigs. Pharmacology & Toxicology 80, 246-250. doi:10.1111/j.1600-0773.1997.tb01967.x
Olds JE (2017) Use of oral fluoxetine for the treatment of abnormal aggression in two red-necked wallabies (Macropus rufogriseus). Journal of Zoo and Wildlife Medicine 48, 922-924.
O’Shea TJ, Clark DR (2002) An overview of contaminants and bats, with special reference to insecticides and the Indiana bat. In The Indiana Bat: Biology and Management of an Endangered Species. (Eds A Kurta and J Kennedy) pp. 237-253. Bat Conservation International, Austin, TX.
Osawa R, Carrick FN (1990) Use of dietary supplement in koalas during systemic antibiotic treatment of chlamydial infection. Australian Veterinary Journal 67, 305-307. doi:10.1111/j.1751-0813.1990. tb07805.x
Osawa R, Bird PS, Harbrow DJ, Ogimoto K, Seymour GJ (1993) Microbiological studies of the intestinal microflora of the koala, Phasco- larctos cinereus. I: Colonisation of the caecal wall by tannin-proteincomplex-degrading enterobacteria. Australian Journal of Zoology 41, 599-609. doi:10.1071/ZO9930599
Pass M, Brown A (1990) Liver function in normal koalas and macropods. Australian Veterinary Journal 67, 151-152. doi:10.1111/ j.1751-0813.1990.tb07739.x
Phalen DN, Frimberger A, Pyecroft S, Peck S, Harmsen C, Lola S, de Mello Mattos B, Li KM, McLachlan AJ, Moore A (2013) Vincristine chemotherapy trials and pharmacokinetics in Tasmanian devils with Tasmanian devil facial tumor disease. PLoS One 8, e65133. doi:10.1371/journal.pone.0065133
Phalen DN, Frimberger AE, Peck S, Pyecroft S, Harmsen C, Lola S, Moore AS (2015) Doxorubicin and carboplatin trials in Tasmanian devils (Sarcophilus harrisii) with Tasmanian devil facial tumor disease. Veterinary Journal (London, England) 206, 312-316. doi:10.1016/j.tvjl.2015.10.013
Ralston MJ, Stankiewicz M, Heath DD (2001) Anthelmintics for the control of nematode infections in the brushtail possum (Trichosu- rus vulpecula). New Zealand Veterinary Journal 49, 73-77. doi:10.1080/00480169.2001.36206
Reid I, McDonald I (1968) Renal function in the marsupial Trichosurus vulpecula. Comparative Biochemistry and Physiology 25, 1071-1079. doi:10.1016/0010-406X(68)90592-6
Rettie AE, Jones JP (2005) Clinical and toxicological relevance of CYP2C9: drug-drug interactions and pharmacogenetics. Annual Review of Pharmacology and Toxicology 45, 477-494. doi:10.1146/ annurev.pharmtox.45.120403.095821
Ruykys L, Breed B, Schultz D, Taggart D (2013) Effects and treatment of sarcoptic mange in southern hairy-nosed wombats (Lasiorhinus latifrons). Journal of Wildlife Diseases 49, 312-320. doi:10.7589/ 2012-10-256
Scheelings TF, Devi JL, Woodward AP, Whittem T (2015) Pharmacokinetics of enrofloxacin following oral and subcutaneous administration in the common ringtail possum (Pseudocheirus peregrinus). Journal of Veterinary Pharmacology and Therapeutics 38, 482-487. doi:10.1111/jvp.12201
Scott G, Field CL, Papich MG, Harms CA (2020) Plasma concentrations of itraconazole following a single oral dose in juvenile California sea lions (Zalophus californianus). Journal of Veterinary Pharmacology and Therapeutics 43, 377-380. doi:10.1111/jvp.12865 Sedgwick CJ (1993) Allometric scaling and emergency care: the importance of body size. In Zoo and Wild Animal Medicine: Current Therapy 3. (Ed. ME Fowler) pp. 34-37. WB Saunders, Philadelphia.
Senn L, Hammerschlag MR, Greub G (2005) Therapeutic approaches to Chlamydia infections. Expert Opinion on Pharmacotherapy 6, 2281-2290. doi:10.1517/14656566.6.13.2281
Simeone CA, Nollens HH, Meegan JM, Schmitt TL, Jensen ED, Papich MG, Smith CR (2014) Pharmacokinetics of single dose oral meloxi- cam in bottlenose dolphins (Tursiops truncatus). Journal of Zoo and Wildlife Medicine 45, 594-599. doi:10.1638/2013-0281R1.1
Sorensen JS, Dearing MD (2006) Efflux transporters as a novel herbivore countermechanism to plant chemical defenses. Journal of Chemical Ecology 32, 1181-1196. doi:10.1007/s10886-006-9079-y
Stegemann M, Sherington J, Coati N, Brown S, Blanchflower S (2006) Pharmacokinetics of cefovecin in cats. Journal of Veterinary Pharmacology and Therapeutics 29, 513-524. doi:10.1111/j.1365-2885. 2006.00795.x
Stupans I, Kong S, Kirlich A, Murray M, Bailey EB, Jones BR, McKinnon RA (1999) Hepatic microsomal enzyme activity in the koala and tammar wallaby: high 17-hydroxysteroid oxidoreductase activity in koala liver microsomes. Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology 123, 67-73. doi:10.1016/S0742-8413(99)00012-2
Stupans I, Jones B, McKinnon RA (2001) Xenobiotic metabolism in Australian marsupials. Comparative Biochemistry and Physiology. Part C: Pharmacology, Toxicology & Endocrinology 128, 367-376. doi:10.1016/S1532-0456(00)00211-8
Takano K, De Hayr L, Carver S, Harvey RJ, Mounsey KE (2023) Pharmacokinetic and pharmacodynamic considerations for treating sarcoptic mange with cross-relevance to Australian wildlife. International Journal for Parasitology: Drugs and Drug Resistance 21, 97-113. doi:10.1016/j.ijpddr.2023.02.004
Takeda K, Manago K, Morita A, Kawai YK, Yasuo N, Sekijima M, Ikenaka Y, Hashimoto T, Minato R, Oyamada Y, Horikoshi K, Suzuki H, Ishizuka M, Nakayama SMM (2022) Toxicokinetic analysis of the anticoagulant rodenticides warfarin & diphacinone in Egyptian fruit bats (Rousettus aegyptiacus) as a comparative sensitivity assessment for bonin fruit bats (Pteropus pselaphon). Ecotoxicology and Environmental Safety 243. doi:10.1016/j. ecoenv.2022.113971
Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC (1987) Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proceedings of the National Academy of Sciences of the United States of America 84, 7735-7738. doi:10.1073/pnas.84.21.7735
Tokonami F, Kimble B, Govendir M (2021) Pharmacokinetic profile of fentanyl in the koala (Phascolarctos cinereus) after intravenous administration, and absorption via a transdermal patch. Animals 11, 3550.
Turck D, Roth W, Busch U (1996) A review of the clinical pharmacokinetics of meloxicam. Rheumatology 35(Suppl 1), 13-16. doi:10.1093/ rheumatology/35.suppl_1.13
Tyden E, Olsen L, Tallkvist J, Larsson P, Tjalve H (2004) CYP3A in horse intestines. Toxicology and Applied Pharmacology 201, 112-119. doi:10.1016/j.taap.2004.05.015
Tyden E, Tallkvist J, Tjalve H, Larsson P (2009) P-glycoprotein in intestines, liver, kidney and lymphocytes in horse. Journal of Veterinary Pharmacology and Therapeutics 32, 167-176. doi:10.1111/j.1365- 2885.2008.01017.x
Vogelnest L, Woods R (Eds) (2008) Medicine of Australian Mammals. CSIRO Publishing, Melbourne.
Watson M, Papich MG, Chinnadurai S (2017) Pharmacokinetics of intravenous clindamycin in captive Bennett’s wallabies (Macropus rufogriseus). Journal of Veterinary Pharmacology and Therapeutics doi:10.1111/jvp.12421.
Wilkinson V, Takano K, Nichols D, Martin A, Holme R, Phalen D, Mounsey K, Charleston M, Kreiss A, Pye R (2021) Fluralaner as a novel treatment for sarcoptic mange in the bare-nosed wombat (Vombatus ursinus): safety, pharmacokinetics, efficacy and practicable use. Parasites & Vectors 14, 1-21.
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