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TUBERCULOUS MYCOBACTERIOSIS IN TERRESTRIAL AUSTRALIAN MAMMALS

Three TM species are known to cause disease in Austral­ian mammals: M. bovis, M. tuberculosis and M. pinnipe- dii. Tuberculosis in pinnipeds is covered in Chapter 45.

Species of significance to terrestrial Australian mam­mals are M.

tuberculosis and M. bovis, although M. tuber­culosis infection has been rarely reported in Australian mammals, most being historic and unconfirmed, with the most recent in three red-necked wallabies (Nota- macropus rufogriseus) (Hime and Jones 1972). Mycobac­terium bovis (bovine tuberculosis) is an economically important, serious disease of bovids worldwide. In NZ, M. bovis is endemic and introduced Australian free- ranging common brush-tailed possums are the primary wildlife reservoir (WHA 2017b). It has never been diag­nosed in a common brush-tailed possum in Australia; M. bovis has been reported in a rufous bettong (Aepyprym- nus rufescens) and a group of red-necked wallabies from London Zoo and Zurich Zoo, respectively (Potkay 1977).

TM are host-dependent and therefore rely on host-to- host transmission, which is usually via the respiratory route. Tuberculous mycobacteriosis in Australian mam­mals resembles that seen in other species, namely pyo- granulomatous nodular pneumonia and/or lymphadenitis. Infection may disseminate systemically (Hime and Jones 1972; Potkay 1977; Nugent et al. 2013). Intralesional AFB may be noted, but TM lesions can have very few micro­scopically detectable organisms and therefore suspected samples should also be submitted for culture and/or PCR for confirmation or confident exclusion. Reports of treat­ment of Australian mammals with tuberculous mycobac- teriosis are limited and historic (Teuscher 1957, cited in Potkay 1977). In nearly all cases the appropriate manage­ment is euthanasia, given the animal welfare implications of long-term treatment and isolation, zoonotic risk and socioeconomic implications of a diagnosis of bovine tuberculosis in Australia. Diseased possums in NZ are not treated (WHA 2017b).

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Source: Vogelnest L., Portas T. (Eds.). Current Therapy in Medicine of Australian Mammals. CSIRO,2025. — 848 p.. 2025

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