ЛИТЕРАТУРА К РАЗДЕЛУ I.

Робинсон МВ, Труфакин ВА.

Апоптоз и цитокины.

Успехи совр биол 1999;119(4):359-367.

Abbud RA, Kelleher R, Melmed S.

Cell-specific pituitary gene expression profiles after treatment with leukemia inhibitory factor reveal novel modulators for proopiomelanocortin expression.

Endocrinology. 2004;145(2):867-880.

Acheson A, Lindsay M.

Diverse roles of neurotrophic factor in health and disease. Seminars in the neuroscience 1994; 6:333-341

Ahlen K, Ring P, Tomasini-Johansson B, Holmqvist K, Magnusson KE, Rubin K.

Platelet-derived growth factor-BB modulates membrane mobility of beta1 integrins. Biochem Biophys Res Commun. 2004;314(1):89-96.

Akerud P, Alberch J, Eketjall S, Wagner J, Arenas E.

Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons.

J Neurochem. 1999l;73(1):70-78.

Akerud P, Holm PC, Castelo-Branco G, Sousa K, Rodriguez FJ, Arenas E.

Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease.

Mol Cell Neurosci. 2002;21(2):205-222.

Akita S, Webster J, Ren SG, Takino H, Said J, Zand O, Melmed S.

Human and murine pituitary expression of leukemia inhibitory factor. Novel intrapituitary regulation of adrenocorticotropin hormone synthesis and secretion.

J Clin Invest. 1995;95(3):1288-1298.

Alberch J, Perez-Navarro E, Canals JM.

Neuroprotection by neurotrophins and GDNF family members in the excitotoxic model of Huntington's disease.

Brain Res Bull. 2002;57(6):817-822.

Allan SM, Pinteaux E.

The interleukin-1 system: an attractive and viable therapeutic target in neurodegenerative disease. Curr Drug Target CNS Neurol Disord. 2003;2(5):293-302.

Aloe L. et al.

Haloperidol administration in humans lowers plasma nerve growth factor level: Evidence that sedation induces opposite effects to arousal.

Neuropsychobiol 1997;36(2):65-68.

Aloe L. et al.

Studies in animal models and human suggesting a role of nerve growth factor in schizophrenia- like disorders.

Behav Pharmacol 2000;11(3-4):235-242.

Anand P.

Neurotrophic factors and their receptors in human sensory neuropathies. Prog Brain Res. 2004;146:477-492.

Anderson KD, Lambert PD, Corcoran TL, Murray JD, Thabet KE, Yancopoulos GD, Wiegand SJ. Activation of the hypothalamic arcuate nucleus predicts the anorectic actions of ciliary neurotrophic factor and leptin in intact and gold thioglucose-lesioned mice.

J Neuroendocrinol. 2003;15(7):649-660.

Andrae J, Molander C, Smits A, Funa K, Nister M.

Platelet-derived growth factor-B and -C and active alpha-receptors in medulloblastoma cells. Biochem Biophys Res Commun. 2002;296(3):604-611.

Andres R, Forgie A, Wyatt S, Chen Q, de Sauvage FJ, Davies AM.

Multiple effects of artemin on sympathetic neurone generation, survival and growth. Development. 2001;128(19):3685-3695.

Anton FS, Marchionni MA, Lee KF, Rakis P.

Role of GGF/neuregulin signalling in interaction between migrating neurones and radial glia in the developing cerebral cortex.

Development. 1997;124(18): 3501-3510.

Aperlo C, Sevilla L, Guerin S, Pognonec P, Boulukos KE.

Synergistic effects of colony-stimulating factor 1 and leukemia inhibitory factor in inducing early myeloid cell differentiation.

Cell Growth Differ. 1998;9(11):929-937.

Araujo DM. & Hilt DC.

Glial cell line-derived neurotrophic factor attenuates the excitotoxin-induced behavioral and neuro- chemical deficits in a rodent model of Huntington's disease.

Neuroscience. 1997;81(4):1099-1110.

Arvanian VL, Horner PJ, Gage FH, Mendell LM.

Chronic neurotrophin-3 strengthens synaptic connections to motoneurons in the neonatal rat. J Neurosci. 2003;23(25):8706-8712.

Avital A, Goshen I, Kamsler A, Segal M, Iverfeldt K, Richter-Levin G, Yirmiya R.

Impaired interleukin-1 signaling is associated with deficits in hippocampal memory processes and neural plasticity.

Hippocampus. 2003;13(7):826-34.

Baloh RH, Tansey MG, Lampe PA, Fahrner TJ, Enomoto H, Simburger KS, Leitner ML Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex.

Neuron. 1998;21(6):1291-302.

Baraczka K, Pozsonyi T, Szuts I, Ormos G, Nekam K.

Increased levels of tumor necrosis alpha and soluble vascular endothelial adhesion molecule-1 in the cerebrospinal fluid of patients with connective tissue diseases and multiple sclerosis.

Acta Microbiol Immunol Hung. 2003;50(4):339-348.

Betsholtz C.

Biology of platelet-derived growth factors in development. Birth Defects Res Part C Embryo Today. 2003;69(4):272-285.

Bezzi P, Domercq M, Brambilla L et al.

CXCR4-activated actrocyte glutamate release via TNF-alpha: ampflication by microglia triggers neurotoxicity. Nat Neurosci 2001;4:702-710.

Biber K, Zuurman MW, Dijkstra I, Boddeke H. Chemokines in the brain: neuroimmunology and beyong. Curr Opinion Pharmacol 2002;2:63-68.

Binder D. et al.

BDNF and epilepsy: too much of a good thing? Trends Neurosci. 2001;24(1):47-53.

Biswas SS, Hughes GC, Scarborough JE, Domkowski PW, et al.

Intramyocardial and intracoronary basic fibroblast growth factor in porcine hibernating myocardium: A comparative study.

J Thorac Cardiovasc Surg. 2004;127(1):34-43.

Blackledge G, Averbuch S.

Gefitinib ('Iressa', ZD1839) and new epidermal growth factor receptor inhibitors. Br J Cancer. 2004;90(3):566-572.

Boutros T. et al.

Interferon-beta is a potent promoter of nerve growth factor production by astrocytes. J Neuroch. 1997;69(3):939-946.

Buzus B, Symes AJ, Cox BM.

Regulation of nociceptin/orphanin FQ gene expression by neuropoetic cytokines and neurotrophic factors in neurons and astrocytes.

J Neurochem 1999; 72(5):1882-1889.

Calikoglu M, Sahin G, Unlu A, Ozturk C, Tamer L, Ercan B, Kanik A, Atik U.

Leptin and TNF-Alpha Levels in Patients with Chronic Obstructive Pulmonary Disease and Their Relationship to Nutritional Parameters.

Respiration. 2004;71(1):45-50.

Campenot RB, MacInnis BL.

Retrograde transport of neurotrophins: Fact and function. J Neurobiol. 2004;58(2):217-229.

Carrascosa C, Torres-Aleman I, Lopez-Lopez C, Carro E, Espejo L, Torrado S, TorradoJ. Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration. Biomaterials. 2004;25(4):707-714.

Cearley C, Churchill L, Krueger JM.

Time of day differences in IL1beta and TNFalpha mRNA levels in specific regions of the rat brain. Neurosci Lett. 2003;352(1):61-63.

Chalazonitis A.

Neurotrophin-3 in the development of the enteric nervous system. Prog Brain Res. 2004;146:243-263.

Chaldakov GN, Fiore M, Stankulov IS, Manni L, Hristova MG, Antonelli A, Ghenev PI, Aloe L. Neurotrophin presence in human coronary atherosclerosis and metabolic syndrome: a role for NGF and BDNF in cardiovascular disease?

Prog Brain Res. 2004;146:279-289.

Che X, Ye W, Panga L et al.

Monocyte chemoattractant protein expressed in neurons and astrocytes during focal ischemia in mice. Brain Res. 2001; 902:171-177.

Chen T, Amons R, Clegg JS, Warner AH, MacRae TH.

Molecular characterization of artemin and ferritin from Artemia franciscana. Eur J Biochem. 2003;270(1):137-145.

Chodobski A, Chung I, Kozniewska E, Ivanenko T, Chang W, Harrington JF, et al.

Early neutrophilic expression of vascular endothelial growth factor after traumatic brain injury. Neuroscience. 2003;122(4):853-867.

Choi SY, Hwang JJ, Koh JY.

NR2A induction and NMDA receptor-dependent neuronal death by neurotrophin-4/5 in cortical cell culture.

J Neurochem. 2004;88(3):708-716.

Chu C, Chen C, Wang SS.

Hepatic encephalopathy in rats with thioacetamide-induced fulminant hepatic failure: role of endotoxin and TNF factor-α.

Zhonghua Yi Xue Za Zhi (Taipei). 2001;64(6):321-330.

Clegg JS, Jackson SA, Popov VI.

Long-term anoxia in encysted embryos of the crustacean, Artemia franciscana: viability, ultrastructure, and stress proteins.

Cell Tissue Res. 2000;301(3):433-446.

Cohen PE, Zhu L, Nishimura K, Pollard JW.

Colony-stimulating factor 1 regulation of neuroendocrine pathways that control gonadal function in mice.

Endocrinology. 2002;143(4):1413-1422.

Corry DB, Kheradmand F.

Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma. Am J Respir Med. 2002;1(3):185-93.

Coumoul X, Deng CX.

Roles of FGF receptors in mammalian development and congenital diseases. Birth Defects Res Part C Embryo Today. 2003;69(4):286-304.

Daftary SS, Gore AC.

The Hypothalamic Insulin-Like Growth Factor-1 Receptor and Its Relationship to Gonadotropin- Releasing Hormones Neurones During Postnatal Development.

J Neuroendocrinol. 2004;16(2):160-169.

Date I. et al.

Long-term enhanced chromaffin cell survival and behavioral recovery in hemiparkinsonian rats with co-grafted polymeren capsulated human NGF-secreting cells.

Exp Neurol 1997;147(1):10-17.

Dechant G, Neumann H.

Neurotrophins.

Adv Exp Med Biol. 2002;513:303-334.

Delcroix J, Valletta J, Wu C, Howe CL, Lai CF, Cooper JD, Belichenko PV, Salehi A, Mobley WC.

Trafficking the NGF signal: implications for normal and degenerating neurons. Prog Brain Res. 2004;146:3-23.

Dempsey RJ, Sailor KA, Bowen KK, Tureyen K, Vemuganti R.

Stroke-induced progenitor cell proliferation in adult spontaneously hypertensive rat brain: effect of exogenous IGF-1 and GDNF.

J Neurochem. 2003;87(3):586-597.

Duberley RM, Johnson IP, Martin JE, Anand P.

RET-like immunostaining of spinal motoneurons in amyotrophic lateral sclerosis. Brain Res. 1998;789(2):351-354.

Emanueli C, Schratzberger P, Kirchmair R, Madeddu P.

Paracrine control of vascularization and neurogenesis by neurotrophins. Br J Pharmacol. 2003;140(4):614-619.

Endres M, Fan G, Hirt L, Jaenisch R.

Stroke damage in mice after knocking the neutrophin-4 gene into the brain-derived neurotrophic factor locus.

J Cereb Blood Flow Metab.

Enge M, Wilhelmsson U, Abramsson A, Stakeberg J, Kuhn R, Betsholtz C, Pekny M.

Neuron-specific ablation of PDGF-B is compatible with normal central nervous system development and astroglial response to injury.

Neurochem Res. 2003;28(2):271-279.

Englesbe MJ, Hawkins SM, Hsieh PC, Daum G, Kenagy RD, Clowes AW.

Concomitant blockade of platelet-derived growth factor receptors alpha and beta induces intimal atrophy in baboon PTFE grafts.

J Vasc Surg. 2004;39(2):440-446.

Erlandsson A. et al.

Immature neurons from CNS stem cells proliferate in response to PDGF. J Neurosci 2001;21(10): 3483-3491.

Eves E. et al.

FGF induces a switch in death receptor pathways in neuronal cells. J Neurosci 2001;21 (14): 4996-5006.

Fabel K, Fabel K, Tam B, Kaufer D, Baiker A, Simmons N, Kuo CJ, Palmer TD.

VEGF is necessary for exercise-induced adult hippocampal neurogenesis. Eur J Neurosci. 2003 Nov;18(10):2803-12.

Fahnestock M, Yu G, Coughlin MD.

ProNGF: a neurotrophic or an apoptotic molecule? Prog Brain Res. 2004;146:107-10.

Fantuzzi G, Benigni F, Sironi M. et al.al.

Ciliary neurotrophic factor (CNTF) induces serum amyloid A, hypoglicaemia and anorexia and potentiates IL-1 induced corticosterone and IL-6 production in mice.

Cytokine 1995;7(2):150-156.

Fiedler R, Deuber HJ, Langer T, Osten B, Mohan S, Jehle PM.

Effects of reduced dialysate calcium on calcium-phosphorus product and bone metabolism in hemodialysis patients.

Nephron Clin Pract. 2004;96(1):3-9.

Figiel M, Maucher T, Rozyczka J, Bayatti N, Engele J.

Regulation of glial glutamate transporter expression by growth factors. Exp Neurol. 2003;183(1):124-135.

Fischer S. et al.

In vitro effects of dexamethasone on hypoxia-induced hyperpermeability and expression of vascular endothelial growth factor,

Eur J Pharmacol 2001;411(3):231-243

Florholmen G, Andersson KB, Yndestad A, Austbo B, Henriksen UL, Christensen G. Leukaemia inhibitory factor alters expression of genes involved in rat cardiomyocyte energy metabolism.

Acta Physiol Scand. 2004;180(2):133-142.

Florio P, Calonaci G, Luisi S, Severi FM, Ignacchiti E, Palumbo M, Bocchi C,Petraglia F.

Inhibin A, inhibin B and activin A concentrations in umbilical cord artery and vein. Gynecol Endocrinol. 2003;17(3):181-185.

Fox C.

Neuroprotective effects of GDNF against 6-OHDA in young and aged rats. Brain Res 2001;896(1-2):56-63.

Freeman RS, Burch RL, Crowder RJ, Lomb DJ, Schoell MC, Straub JA, Xie L.

NGF deprivation-induced gene expression: after ten years, where do we stand? Prog Brain Res. 2004;146:111-126.

Freund V, Frossard N.

Expression of nerve growth factor in the airways and its possible role in asthma. Prog Brain Res. 2004;146:335-346.

Friguls B, Petegnief V, Justicia C, Pallas M, Planas AM.

Activation of ERK and Akt signaling in focal cerebral ischemia: modulation by TGF-alpha and involvement of NMDA receptor.

Neurobiol Dis. 2002;11(3):443-456.

Fu P, Sodian R, Luders C, Lemke T, Kraemer L, et al.

Effects of basic fibroblast growth factor and transforming growth factor-beta on maturation of human pediatric aortic cell culture for tissue engineering of cardiovascular structures.

ASAIO J. 2004;50(1):9-14.

Fumagalli F, Bedogni F, Maragnoli ME, Gennarelli M, Perez J, Racagni G, Riva MA. Dopaminergic D2 receptor activation modulates FGF-2 gene expression in rat prefrontal cortex and hippocampus.

J Neurosci Res. 2003;74(1):74-80.

Futamura T, Toyooka K, Iritani S, Niizato K, Nakamura R, Tsuchiya K, et al.

Abnormal expression of epidermal growth factor and its receptor in the forebrain and serum of schizophrenic patients.

Mol Psychiatry. 2002;7(7):673-682.

Gabriel C, Ali C, Lesne S, Fernandez-Monreal M, Docagne F, Plawinski L, Buisson A, Vivien D. Transforming growth factor alpha-induced expression of type 1 plasminogen activator inhibitor in astrocytes rescues neurons from excitotoxicity.

FASEB J. 2003;17(2):277-9.

Galbiati M, Martini L, Melcangi RC.

Oestrogens, via transforming growth factor alpha, modulate basic fibroblast growth factor synthesis in hypothalamic astrocytes: in vitro observations.

J Neuroendocrinol. 2002;14(10):829-835.

Gardell LR, Wang R, Ehrenfels C, Ossipov MH, Rossomando AJ, et al.

Multiple actions of systemic artemin in experimental neuropathy. Nat Med. 2003;9(11):1383-1389.

Glass DJ, Yancopoulos GD.

The neurotrophins and their receptors. Trends Cell Biol. 1993;3(8):262-268.

Glebova NO, Ginty DD.

Heterogeneous requirement of NGF for sympathetic target innervation in vivo. J Neurosci. 2004;24(3):743-751.

Golden J, Baloh RH, Kotzbauer PT, Lampe PA, Osborne PA, Milbrandt J, Johnson EM Jr.

Expression of neurturin, GDNF, and their receptors in the adult mouse CNS. J Comp Neurol. 1998;398(1):139-150.

Golden JP, Milbrandt J, Johnson EM Jr.

Neurturin and persephin promote the survival of embryonic basal forebrain cholinergic neurons in vitro. Exp Neurol. 2003;184(1):447-455.

van Golen CM. et al.

Pten/mmac1 overexpression decreases insulin-like growth factor-i-mediated protection from apoptosis in neuroblastoma cells.

Cell Growth Differ. 2001;12(7): 371-378.

Gospodarowicz D et al.

Isolation of brain fibroblast growth factor by heparin-Cepharose affinity chromatography: identity with pituitary fibroblast growth factor.

PNAS. 1984;81:6963-6967.

Gratto KA, Verge VM.

Neurotrophin-3 down-regulates trkA mRNA, NGF high-affinity binding sites, and associated phenotype in adult DRG neurons.

Eur J Neurosci. 2003;18(6):1535-1548.

Grazul-Bilska AT, Johnson ML, Bilski JJ, Redmer DA, Reynolds LP, Abdullah A, Abdullah KM.

Wound healing: the role of growth factors. Drugs Today (Barc). 2003;39(10):787-800.

Green-Sadan T, Kinor N, Roth-Deri I, Geffen-Aricha R, Schindler CJ, Yadid G. Transplantation of glial cell line-derived neurotrophic factor-expressing cells into the striatum and nucleus accumbens attenuates acquisition of cocaine self-administration in rats.

Eur J Neurosci. 2003;18(7):2093-2098.

Gregg C, Weiss S.

Generation of functional radial glial cells by embryonic and adult forebrain neural stem cells. J Neurosci. 2003;23(37):11587-11601.

Grondin R, Zhang Z, Ai Y, Gash DM, Gerhardt GA.

Intracranial delivery of proteins and peptides as a therapy for neurodegenerative diseases. Prog Drug Res. 2003;61:101-123.

Grunwald IC, Korte M, Adelmann G, Plueck A, Kullander K, Adams RH, et al.

Hippocampal plasticity requires postsynaptic ephrinBs. Nat Neurosci. 2004;7(1):33-40.

Guan J, Bennet L, Gluckman PD, Gunn AJ.

Insulin-like growth factor-1 and post-ischemic brain injury. Prog Neurobiol. 2003;70(6):443-462.

Guideri F, Acampa M, Calamandrei G, Aloe L, Zappella M, Hayek Y.

Nerve Growth Factor Plasma Levels and Ventricular Repolarization in Rett Syndrome. Pediatr Cardiol. 2004 Jan [Epub ahead of print]

Hai J, Li ST, Lin Q, Pan QG, Gao F, Ding MX.

Vascular endothelial growth factor expression and angiogenesis induced by chronic cerebral hypoperfusion in rat brain.

Neurosurgery. 2003;53(4):963-970.

Hamilton JA, Whitty G, White AR, Jobling MF, Thompson A, Barrow CJ, et al.

Alzheimer's disease amyloid beta and prion protein amyloidogenic peptides promote macrophage survival, DNA synthesis and enhanced proliferative response to CSF-1 (M-CSF).

Brain Res. 2002;940(1-2):49-54.

Hao AJ, Dheen ST, Ling et al.

Expression of macrophage colony-stimulating factor and its receptor in microglia activation is linked to teratogen-induced neuronal damage.

Neuroscience. 2002;112(4):889-900.

Hayashi M, Ohkura T, Inaba N.

Elevation of serum macrophage colony-stimulating factor before the clinical manifestations of preeclampsia.

Am J Obstet Gynecol. 2003;189(5):1356-1360.

Hayes AJ, Mostyn-Jones A, Koban MU, A'Hern R, Burton P, Thomas JM. Serum vascular endothelial growth factor as a tumour marker in soft tissue sarcoma. Br J Surg. 2004;91(2):242-247.

Heaton MB, Paiva M, Madorsky I, Mayer J, Moore DB.

Effects of ethanol on neurotrophic factors, apoptosis-related proteins, endogenous antioxidants, and reactive oxygen species in neonatal striatum: relationship to periods of vulnerability.

Brain Res Dev Brain Res. 2003;140(2):237-252.

Herzog CD, Otto T.

Administration of transforming growth factor-alpha enhances anatomical and behavioral recovery following olfactory nerve transection.

Neuroscience. 2002;113(3):569-580.

Hibbert AP, Morris SJ, Seidah NG, Murphy RA.

Neurotrophin-4, alone or heterodimerized with brain-derived neurotrophic factor, is sorted to the constitutive secretory pathway.

J Biol Chem. 2003;278(48):48129-48136.

Hiney JK, Dearth RK, Srivastava V, Rettori V, Dees WL.

Actions of ethanol on epidermal growth factor receptor activated luteinizing hormone secretion. J Stud Alcohol. 2003;64(6):809-816.

Hoane MR, Gulwadi AG, Morrison S, Hovanesian G, Lindner MD, Tao W. Differential in vivo effects of neurturin and glial cell-line-derived neurotrophic factor. Exp Neurol. 1999;160(1):235-243.

Holm PC, Akerud P, Wagner J, Arenas E.

Neurturin is a neuritogenic but not a survival factor for developing and adult central noradrenergic neurons.

J Neurochem. 2002;81(6):1318-1327.

Hong T. et al.

Expression of angiogenic factors and apoptotic factors in leiomyosarcoma and leiomyoma. Int J Mol Med 2001;8(2):141-148

Honma Y, Araki T, Gianino S, Bruce A, Heuckeroth R, Johnson E, Milbrandt J. Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons. Neuron. 2002;35(2):267-282.

Horger BA, Nishimura MC, Armanini MP, Wang LC, et al.

Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. J Neurosci. 1998;18(13):4929-4937.

Hudgins SN, Levison SW.

Ciliary neurotrophic factor stimulates astroglial hypertriphy in vivo and in vitro. Exp Neurol 1998;150(2):171-182.

Hudkins KL, Gilbertson DG, Carling M, Taneda S, Hughes SD, Holdren MS, et al.

Exogenous PDGF-D Is a Potent Mesangial Cell Mitogen and Causes a Severe Mesangial Proliferative Glomerulopathy.

J Am Soc Nephrol. 2004;15(2):286-298.

Ibanez CF.

Emerging themes in structural biology of neurotrophic factors. TINS 1998;21(10):438-443.

Intiso D, Zarrelli MM, Lagioia G, Di Rienzo F, Checchia De Ambrosio C, et al.

Tumor necrosis factor alpha serum levels and inflammatory response in acute ischemic stroke patients.

Neurol Sci. 2004;24(6):390-396.

Irie F, Yamaguchi Y.

EPHB receptor signaling in dendritic spine development. Front Biosci. 2004;9:1365-1373.

Isono M, Goda M, Kobayashi H, Wu JL.

TGF-alpha overexpression induces astrocytic hypertrophy after cortical stab wound injury. Neurol Res. 2003;25(5):546-550.

Iwadate H, Sugisaki T, Kudo M, Kizuki K.

Actions of insulin-like growth factor binding protein-5 (IGFBP-5) are potentially regulated by tissue kallikrein in rat brains. Life Sci. 2003;73(24):3149-3158.

Iwasaki W, Nagata K, Inui T, kimura T. et al.

Solutions structure of midkine, new heparin-binding growth factor. EMBO J 1997;16(23):6936-6946.

Javaid MK, Godfrey KM, Taylor P, Shore SR, Breier B, Arden NK, Cooper C. Umbilical venous IGF-1 concentration, neonatal bone mass, and body composition. J Bone Miner Res. 2004;19(1):56-63.

Josko J.

Cerebral angiogenesis and expression of VEGF after subarachnoid hemorrhage (SAH) in rats. Brain Res. 2003;981(1-2):58-69.

Josko J, Knefel K.

The role of vascular endothelial growth factor in cerebral oedema formation. Folia Neuropathol. 2003;41(3):161-166.

Jovanovic JN, Thomas P, Kittler JT, Smart TG, Moss SJ.

Brain-derived neurotrophic factor modulates fast synaptic inhibition by regulating GABA(A) receptor phosphorylation, activity, and cell-surface stability.

J Neurosci. 2004;24(2):522-530.

Jungbluth S., Koentges G., Lunsden A.

Coordination of early neural tube development by BDNF/Trk-В. Development 1997;124(10):1877-1885.

Kabasawa Y.

[The expression pattern of the chick pleiotrophin and its possible role in early embryogenesis] Kokubyo Gakkai Zasshi. 2002;69(3):215-223.

Kadokami T. et al.

Antitumor necrosis factor-alpha antibody limits heart failure in a transgenic model. Circulation 2001;104(10):1094-1097.

Kalisch BE, Demeris CS, Ishak M, Rylett RJ.

Modulation of nerve growth factor-induced activation of MAP kinase in PC12 cells by inhibitors of nitric oxide synthase.

J Neurochem. 2003;87(6):1321-1332.

Kanda S, Miyata Y, Kanetake H.

Fibroblast growth factor-2-mediated capillary morphogenesis of endothelial cells requires signals via Flt-1/vascular endothelial growth factor receptor-1: possible involvement of c-Akt.

J Biol Chem. 2004;279(6):4007-4016.

Kaplan F, Comber J, Sladek R, Hudson TJ, Muglia LJ, Macrae T, Gagnon S, et al.

The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development. Am J Respir Cell Mol Biol. 2003;28(1):33-41.

Kariagina A, Romanenko D, Ren SG, Chesnokova V.

Hypothalamic-pituitary cytokine network. Endocrinology. 2004;145(1):104-112.

Kataoka H, Igarashi H, Kanamori M, Ihara M, Wang JD, Wang YJ, et al.

Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer. Cancer Sci. 2004;95(2):136-141.

Katoh-Semba R, Ichisaka S, Hata Y, Tsumoto T, Eguchi K, et al.

NT-4 protein is localized in neuronal cells in the brain stem as well as the dorsal root ganglion of embryonic and adult rats.

J Neurochem. 2003;86(3):660-668.

Kawamoto K, Matsuda H.

Nerve growth factor and wound healing. Prog Brain Res. 2004;146:369-384.

Kazanis I, Bozas E, Philippidis H, Stylianopoulou F.

Neuroprotective effects of insulin-like growth factor-I (IGF-I) following a penetrating brain injury in rats. Brain Res. 2003;991(1-2):34-45.

Khaibullina AA, Rosenstein JM, Krum JM.

Vascular endothelial growth factor promotes neurite maturation in primary CNS neuronal cultures. Brain Res Dev Brain Res. 2004;148(1):59-68.

Kim DH, Zhao X, Tu CH, Casaccia-Bonnefil P, Chao MV.

Prevention of apoptotic but not necrotic cell death following neuronal injury by neurotrophins signaling through the tyrosine kinase receptor.

J Neurosurg. 2004;100(1):79-87.

Kirik D, Georgievska B, Bjorklund A.

Localized striatal delivery of GDNF as a treatment for Parkinson disease. Nat Neurosci. 2004 Feb;7(2):105-10.

Klein P, Mattoon D, Lemmon MA, Schlessinger J.

A structure-based model for ligand binding and dimerization of EGF receptors. Proc Natl Acad Sci U S A. 2004;101(4):929-934.

Koeberle PD, Ball AK.

Neurturin enhances the survival of axotomized retinal ganglion cells in vivo: combined effects with glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor.

Neuroscience. 2002;110(3):555-567.

Kojima K, Kanzaki H, Iwai M, Hatayama H, Fujimoto M, Inoue T. et al. Expression of leukemia inhibitory factor in human endometrium and placenta. Biol Reprod. 1994;50(4):882-887.

Kollermann J, Helpap B.

Expression of vascular endothelial growth factor (VEGF) and VEGF receptor Flk-1 in benign, premalignant, and malignant prostate tissue.

Am J Clin Pathol. 2001;116(1):115-121

Korhonen L, Riikonen R, Nawa H, lindsholm D.

Brain-derived neutrophic factor is increased in cerebrospinal fluid of children suffering from asphixia. Neurosci Lett. 1998;240(3):151-154.

Kozlowski L, Zakrzewska I, Tokajuk P, Wojtukiewicz MZ.

Concentration of interleukin-6 (IL-6), interleukin-8 (IL-8) and interleukin-10 (IL-10) in blood serum of breast cancer patients.

Rocz Akad Med Bialymst. 2003;48:82-84.

Kreider BQ, Grinspan IB, Watersone MB, Bramblett GF. et al.

Partial purification of a novel mitogen for oligodendroglia. J Neurosci Res. 1995;40(1):44-53.

de Kretser DM, Hedger MP, Loveland KL, Phillips DJ.

Inhibins, activins and follistatin in reproduction. Hum Reprod Update. 2002;8(6):529-541.

Kubota K, Suzuki M, Yamanouchi K, Takahashi M, Nishihara M.

Involvement of activin and inhibin in the regulation of food and water intake in the rat. J Vet Med Sci. 2003;65(2):237-242.

Kullander K. et al.

Molecular phylogeny and evolution of the neurotrophins from monotremes and marsupials. J Mol Evol 1997; 45(3):311-321.

La Rosa S, Uccella S, Marchet S, Capella C, Lloyd RV.

Localization of inhibins and activins in normal endocrine cells and endocrine tumors of the gut and pancreas: an immunohistochemical and in situ hybridization study.

J Histochem Cytochem. 2004;52(2):217-225.

Lachapelle F, Avellana-Adalid V, Nait-Oumesmar B, Baron-Van Evercooren A.

Fibroblast growth factor-2 (FGF-2) and platelet-derived growth factor AB (PDGF AB) promote adult SVZ-derived oligodendrogenesis in vivo.

Mol Cell Neurosci. 2002;20(3):390-403.

Lai KO, Chen Y, Po HM, Lok KC, Gong K, Ip NY.

Identification of the Jak/Stat proteins as novel downstream targets of EphA4 signaling in muscle: Implications in the regulation of acetylcholinesterase expression.

J Biol Chem. 2004 Jan 15/

Laurikainen A, Hiltunen JO, Thomas-Crusells J, Vanhatalo S, Arumae U, et al.

Neurturin is a neurotrophic factor for penile parasympathetic neurons in adult rat. J Neurobiol. 2000;43(2):198-205.

Lee LM, Huang MC, Chuang TY, Lee LS, Cheng H, Lee IH. Acidic FGF enhances functional regeneration of adult dorsal roots. Life Sci. 2004;74(15):1937-1943.

Leitner ML, Molliver DC, Osborne PA, Vejsada R, Golden JP, Lampe PA, et al.

Analysis of the retrograde transport of glial cell line-derived neurotrophic factor (GDNF), neurturin, and persephin suggests that in vivo signaling for the GDNF family is GFRalpha coreceptor-specific.

J Neurosci. 1999;19(21):9322-9331.

Lessmann V, Gottmann K, Malcangio M.

Neurotrophin secretion: current facts and future prospects. Prog Neurobiol. 2003;69(5):341-374.

Li H, He Z, Su T, Ma Y, Lu S, Dai C, Sun M.

Protective action of recombinant neurturin on dopaminergic neurons in substantia nigra in a rhesus monkey model of Parkinson's disease.

Neurol Res. 2003;25(3):263-267.

Li SH, Zeng ZM, Lai GC, Li LY.

[The level of serum tumor necrosis factor-alpha and epidermal growth factor in patients with medicamentlike dermatitis by trichloroethylene and its clinical significance]

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2003;21(6):437-439.

Li X, Sankrithi N, Davis FC.

Transforming growth factor-alpha is expressed in astrocytes of the suprachiasmatic nucleus in hamster: role of glial cells in circadian clocks.

Neuroreport. 2002;13(16):2143-2147.

Liang AH, Xue BY, Li CY, Wang JH, Wang L.

[Inhibitory effect of artemin on endotoxin-induced nitric oxide synthesis] Zhongguo Zhong Yao Za Zhi. 2001;26(11):770-773.

Liao SL, Chen WY, Raung SL, Chen CJ.

Ethanol attenuates ischemic and hypoxic injury in rat brain and cultured neurons. Neuroreport. 2003;14(16):2089-2094.

Limatola C, Giovannelli A, Maggi L. et al.

SDF-1alpha –mediated modulation of synaptic transmission in rat cerebellum. Eur J Neurosci 2000;12:2497-2504.

Lin L, Doherty D, Lile J, Bektesh S, Collins F.

GDNF: a glial cell-line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 1993;260:1130-1132.

Liu X. et al.

Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion.

Neurosci Lett 2001;308(2):91-94.

Liu XE, Sun XD, Wu JM.

Expression and significance of VEGF-C and FLT-4 in gastric cancer. World J Gastroenterol. 2004;10(3):352-355.

Lobner D, Golner S, Hjelmhaug J.

Neurotrophic factor effects on oxidative stress-induced neuronal death. Neurochem Res. 2003;28(5):749-756.

Lokker NA, Sullivan CM, Hollenbach SJ, Israel MA, Giese NA.

Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.

Cancer Res. 2002;62(13):3729-3735.

Lucarelli P, Piciullo A, Verdecchia M, Palmarino M, Arpino C, Curatolo P.

The role of -850 tumor necrosis factor-alpha and apolipoprotein E genetic polymorphism in patients with Down's syndrome-related dementia.

Neurosci Lett. 2003;352(1):29-32.

Lucas G, Hendolin P, Harkany T, Agerman K, et al.

Neurotrophin-4 mediated TrkB activation reinforces morphine-induced analgesia. Anat Histol Embryol. 2003;32(4):253-256.

Lucini C, Costagliola C, Borzacchiello G, Castaldo L.

Neurotrophin 3 and its receptor TrkC immunoreactivity in glucagon cells of buffalo pancreas. Nat Neurosci. 2003;6(3):221-222.

Lupien SB, Bluhm EJ, Ishii DN.

Systemic insulin-like growth factor-I administration prevents cognitive impairment in diabetic rats, and brain IGF regulates learning/memory in normal adult rats.

J Neurosci Res. 2003;74(4):512-523.

Ma N, Wu SS, Ma YX, Wang X, Zeng J, Tong G, Huang Y, Wang S.

Nerve growth factor receptor-mediated gene transfer. Mol Ther. 2004;9(2):270-281.

Ma Q, Jones D, Borghesani PR et al.

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4 and SDF-1-decient mice.

Proc Nat Acad Sci USA 1998;95:9448-9453.

Mackay KB, Loddick SA, Naeve GS, Vana AM, Verge GM, Foster AC.

Neuroprotective effects of insulin-like growth factor-binding protein ligand inhibitors in vitro and in vivo. J Cereb Blood Flow Metab. 2003;23(10):1160-1167.

Mackiewicz A, Wiznerowicz M, Roeb E, Karczewska A, Nowak J, Heinrich P, Rose S.

Soluble interleukin 6 receptor is biologically active in vivo. Cytokine. 1995;7(2):142-149.

Marco S, Perez-Navarro E, Tolosa E, Arenas E, Alberch J.

Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease.

J Neurobiol. 2002;50(4):323-332.

Marques MJ, Neto HS.

Ciliary neurotrophic factor stimulates in vivo myotube formation in mice. Neurosci Lett 1997;234(1):43-46.

Mason I.

The RET receptor tyrosine kinase: activation, signalling and significance in neural development and disease.

Pharm Acta Helv. 2000;74(2-3):261-264.

Masure S, Geerts H, Cik M, Hoefnagel E, Van Den Kieboom G, et al.

Enovin, a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells. Existence and tissue-specific expression of different splice variants.

Eur J Biochem. 1999;266(3):892-902.

Matsuura O, Kadomatsu K, Takei Y, Uchimura K, Mimura S, Watanabe K, Muramatsu T.

Midkine expression is associated with postnatal development of the lungs. Cell Struct Funct. 2002;27(2):109-115.

Meng SZ, Oka A, Takashima S.

Developmental expression of monocyte chemoattractant protein-1 in human cerebellum and brainstem.

Brain Dev 1999;21:30-35

Mentlein R, Held-Feindt J.

Pleiotrophin, an angiogenic and mitogenic growth factor, is expressed in human gliomas. J Neurochem. 2002;83(4):747-753.

Merighi A, Carmignoto G, Gobbo S, Lossi L, Salio C, Vergnano AM, Zonta M.

Neurotrophins in spinal cord nociceptive pathways. Prog Brain Res. 2004;146:291-321.

Michel U, Gerber J, E O'Connor A, Bunkowski S, Bruck W, Nau R, Phillips DJ.

Increased activin levels in cerebrospinal fluid of rabbits with bacterial meningitis are associated with activation of microglia.

J Neurochem. 2003;86(1):238-245.

Min KJ, Jou I, Joe E.

Plasminogen-induced IL-1beta and TNF-alpha production in microglia is regulated by reactive oxygen species.

Biochem Biophys Res Commun. 2003;312(4):969-974.

Mitrasinovic OM, Perez GV, Zhao F, Lee YL, Poon C, Murphy GM Jr.

Overexpression of macrophage colony-stimulating factor receptor on microglial cells induces an inflammatory response.

J Biol Chem. 2001;276(32):30142-30149.

Mogi M. et al.

Glial cell line-derived neurotrophic factor in the substantia nigra from control and parkinsonian brains. Neurosci Lett 2001;300(3):179-181.

Morrisey EE, Savani RC.

Midkine: a potential bridge between glucocorticoid and retinoid effects on lung vascular development. Am J Respir Cell Mol Biol. 2003;28(1):5-8.

Mousa MA, Mousa SA.

Immunohistochemical localization of inhibin and activin-like proteins in the brain, pituitary gland, and the ovary of thin-lipped grey mullet, Liza ramada (Risso).

Gen Comp Endocrinol. 2003;132(3):434-43.

Mu D, Jiang X, Sheldon RA, Fox CK, Hamrick SE, Vexler ZS, Ferriero DM.

Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model.

Neurobiol Dis. 2003;14(3):524-534.

Muramatsu T.

Midkine and pleiotrophin: two related proteins involved in development, survival, inflammation and tumorigenesis. J Biochem (Tokyo). 2002;132(3):359-571.

Murase S, Hayashi Y.

Neuronal expression of macrophage colony stimulating factor in Purkinje cells and olfactory mitral cells of wild-type and cerebellar-mutant mice.

Proc Natl Acad Sci U S A. 2004;101(5):1206-1210.

Musaro A, Giacinti C, Borsellino G, Dobrowolny G, Pelosi L, Cairns L, Ottolenghi S, et al. Stem cell-mediated muscle regeneration is enhanced by local isoform of insulin-like growth factor 1. Histochem J. 2002;34(1-2):85-95.

Myers RR, Sekiguchi Y, Kikuchi S, Scott B, Medicherla S, Protter A, Campana WM.

Inhibition of p38 MAP kinase activity enhances axonal regeneration. Exp Neurol. 2003 ;184(2):606-614.

Nagano M, Sakai A, Takahashi N, Umino M, Yoshioka K, Suzuki H.

Decreased expression of glial cell line-derived neurotrophic factor signaling in rat models of neuropathic pain. Br J Pharmacol. 2003;140(7):1252-1260.

Nassenstein C, Braun A, Erpenbeck VJ, Lommatzsch M, Schmidt S, Krug N, et al.

The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma.

J Exp Med. 2003;198(3):455-467.

Negro A, Brar BK, Lee KF.

Essential Roles of Her2/erbB2 in Cardiac Development and Function. Recent Prog Horm Res. 2004;59:1-12.

Ng PC, Lam CW, Li AM, Wong CK, Cheng FW, Leung TF, et al.

Inflammatory cytokine profile in children with severe acute respiratory syndrome. Pediatrics. 2004;113(1 Pt 1):7-14.

Nicole O. et al.

Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway.

J Neurosci 2001;21(9):3024-3033.

Nieder C, Schlegel J, Andratschke N, Thamm R, Grosu AL, Molls M.

The role of growth factors in central nervous system tumours. Anticancer Res. 2003;23(2C):1681-1686.

Nishishita T, Lin PC.

Angiopoietin 1, PDGF-B, and TGF-beta gene regulation in endothelial cell and smooth muscle cell interaction.

J Cell Biochem. 2004;91(3):584-593.

Nobuaku M, Masaharu N.

Involvement of receptor-like protein tyrosine phosphatase zeta/RPTPbeta and its ligand pleotrophin/heparin-binding growth associated molecule (HB-GAM) in neuronal migration. J Cell Biol. 1998;142:203.

Oiwa Y, Yoshimura R, Nakai K, Itakura T.

Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, iochemical and histochemical measurements in a model of progressive Parkinson's disease. Brain Res. 2002;947(2):271-283.

Owada K, Sanjyo N, Kobayashi T, Kamata T, Mizusawa H, et al.

Midkine inhibits apoptosis via extracellular signal regulated kinase (ERK) activation in PC12 cells. J Med Dent Sci. 1999;46(1):45-51.

Park SH, Heo JS, Kang CW.

Dose-dependent effect of alcohol on insulin-like growth factor systems in male rats. Clin Exp Pharmacol Physiol. 2004;31(1-2):22-28.

Paule B, Brion N.

[EGF receptors in urological cancer. Molecular basis and therapeutic involvements] Ann Med Interne (Paris). 2003;154(7):448-456.

Perez-Garcia MJ, ;Cena V, De Pablo Y, Llovera M, Comella JX, Soler RM.

Glial cell line-derived neurotrophic factor increases intracellular calcium concentration: role of calcium/calmodulin in the activation of the phosphatidylinositol 3-kinase pathway.

J Biol Chem. 2003 Nov 20/ Epub.

Perez-Martin M, Azcoitia I, Trejo JL, Sierra A, Garcia-Segura LM.

An antagonist of estrogen receptors blocks the induction of adult neurogenesis by insulin-like growth factor-I in the dentate gyrus of adult female rat.

Eur J Neurosci. 2003;18(4):923-930.

Perez-Navarro E, Akerud P, Marco S, Canals JM, Tolosa E, Arenas E, Alberch J.

Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease.

Neuroscience. 2000;98(1):89-96.

Pichiule P, Agani F, Chavez JC, Xu K, LaManna JC.

HIF-1 alpha and VEGF expression after transient global cerebral ischemia. Adv Exp Med Biol. 2003;530:611-617.

Pidgeon GP. et al.

Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells.

Br J Cancer 2001;85(2):273-278

Pitzer MR, Sortwell CE, Daley BF, McGuire SO, Marchionini D, Fleming M, Collier TJ. Angiogenic and neurotrophic effects of vascular endothelial growth factor (VEGF165): studies of grafted and cultured embryonic ventral mesencephalic cells.

Exp Neurol. 2003;182(2):435-445.

Powers JF, Schelling KH, Tischler AS.

Chromaffin cell mitogenesis by neurturin and glial cell line-derived neurotrophic factor. Neuroscience. 2001;108(2):341-349.

Pufe T, Bartscher M, Petersen W, Tillmann B, Mentlein R.

Expression of pleiotrophin, an embryonic growth and differentiation factor, in rheumatoid arthritis. Arthritis Rheum. 2003;48(3):660-667.

Pufe T, Bartscher M, Petersen W, Tillmann B, Mentlein R.

Pleiotrophin, an embryonic differentiation and growth factor, is expressed in osteoarthritis. Osteoarthritis Cartilage. 2003;11(4):260-264.

Ramer MS, Bradbury EJ, Michael GJ, Lever IJ, McMahon SB.

Glial cell line-derived neurotrophic factor increases calcitonin gene-related peptide immunoreactivity in sensory and motoneurons in vivo.

Eur J Neurosci. 2003;18(10):2713-2721.

Ran S, Huang X, Downes A, Thorpe PE.

Evaluation of novel antimouse VEGFR2 antibodies as potential antiangiogenic or vascular targeting agents for tumor therapy.

Neoplasia. 2003;5(4):297-307.

Remy S, Naveilhan P, Brachet P, Neveu I.

Differential regulation of GDNF, neurturin, and their receptors in primary cultures of rat glial cells. J Neurosci Res. 2001;64(3):242-251.

Renner O, Tsimpas A, Kostin S, Valable S, Petit E, Schaper W, Marti HH.

Time- and cell type-specific induction of platelet-derived growth factor receptor-beta during cerebral ischemia.

Brain Res Mol Brain Res. 2003;113(1-2):44-51.

Rodger J, Vitale PN, Tee LB, King CE, Bartlett CA, Fall A, et al.

EphA/ephrin-A interactions during optic nerve regeneration: restoration of topography and regulation of ephrin-A2 expression.

Mol Cell Neurosci. 2004;25(1):56-68.

Rosenstein JM, Mani N, Khaibullina A, Krum JM.

Neurotrophic effects of vascular endothelial growth factor on organotypic cortical explants and primary cortical neurons.

J Neurosci. 2003;23(35):11036-11044.

Rossi J, Tomac A, Saarma M, Airaksinen MS.

Distinct roles for GFRalpha1 and GFRalpha2 signalling in different cranial parasympathetic ganglia in vivo.

Eur J Neurosci. 2000;12(11):3944-3952.

Roth SM, Metter EJ, Lee MR, Hurley BF, Ferrell RE.

C174T polymorphism in the CNTF receptor gene is associated with fat-free mass in men and women. J Appl Physiol. 2003;95(4):1425-1430.

Rowinsky EK.

The erbB Family: Targets for Therapeutic Development Against Cancer and Therapeutic Strategies Using Monoclonal Antibodies and Tyrosine Kinase Inhibitors.

Annu Rev Med. 2004;55:433-457.

Saarma M.

GDNF - a stranger in the TGF-beta superfamily? Eur J Biochem. 2000;267(24):6968-6971.

Sack FU, Vielfort TJ, Koch A, Haass M, Taylor S, Otto HF, Hagl S, Schnabel PA.

The role of platelet derived growth factor in endomyocardial biopsies shortly after heart transplantation in relation to postoperative course.

Eur J Cardiothorac Surg. 2004;25(1):91-97.

Salhia B. et al.

Expression of vascular endothelial growth factor by reactive astrocytes and associatedneo angiogenesis. Brain Res 2000;883(1):87-97.

Sapi E.

The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update. Exp Biol Med (Maywood). 2004;229(1):1-11.

Sato W, Yuzawa Y, Kadomatsu K, Tayasu T, Muramatsu H, Muramatsu T, Matsuo S. Midkine expression in the course of nephrogenesis and its role in ischaemic reperfusion injury. Nephrol Dial Transplant. 2002;17, Suppl 9:52-54.

Savolainen-Peltonen H, Loubtchenkov M, Petrov L, Delafontaine P, Hayry P.

Estrogen regulates insulin-like growth factor 1, platelet-derived growth factor A and B, and their receptors in the vascular wall. Transplantation. 2004;77(1):35-42.

Schreiber RC, Krivacic K, Kirby B et al.

Monocyte chemoattractant protein (MCP-1) is rapidly expressed by sympathetic ganglion neurons following axonal injury.

Mol Neurosci 2000;12:601-605.

Schwob JE.

Neural regeneration and the peripheral olfactory system. Anat Rec. 2002;269(1):33-49.

Sharma S, Oomizu S, Kakeya T, Masui T, Takeuchi S, Takahashi S.

Gene expression and the physiological role of transforming growth factor-alpha in the mouse pituitary. Zoolog Sci. 2003;20(1):83-89.

Shimomura A, Nomura R, Senda T.

Lithium inhibits apoptosis of mouse neural progenitor cells. Neuroreport. 2003;14(14):1779-1782.

Silveira RC, Procianoy RS.

Interleukin-6 and tumor necrosis factor-alpha levels in plasma and cerebrospinal fluid of term newborn infants with hypoxic-ischemic encephalopathy.

J Pediatr. 2003;143(5):625-629.

Skold M. et al.

Induction of VEGF and VEGF receptors in the spinal cord after mechanical spinal injury and prostaglandin administration.

Eur J Neurosci. 2000;12(10):3675-3686.

Skovronsky DM, Fath S, Lee VM, Milla ME.

Neuronal localization of the TNFalpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques/

J Neurobiol. 2001;49(1):40-46.

Smith DJ, Leil TA, Liu X.

Neurotrophin-4 is required for tolerance to morphine in the mouse. Neurosci Lett. 2003;340(2):103-106.

Smith PF.

Neuroprotection against hypoxia-ischemia by insulin-like growth factor-I (IGF-I). Drugs. 2003;6(12):1173-1177.

Sobreviela T. ea,

Retrograde transport of BDNF following infusion in neo- and limbic cortex in rat: relationship to BDNF mRNA expressing neurons.

J Compar Neurol. 1996;375(3):417-444.

Song C, Phillips AG, Leonard B.

Interleukin 1 beta enhances conditioned fear memory in rats: possible involvement of glucocorticoids. Eur J Neurosci. 2003;18(7):1739-1743.

Stover JF, Sakowitz OW, Schoning B, Rupprecht S, Kroppenstedt SN, et al.

Norepinephrine infusion increases interleukin-6 in plasma and cerebrospinal fluid of brain-injured rats. Med Sci Monit. 2003;9(10):BR382-8.

Subauste MC, Proud D.

Effects of tumor necrosis factor-alpha, epidermal growth factor and trans-forming growth factor-alpha on interleukin-8 production by, and human rhinovirus replication in bronchial epithelial cells. Int Immunopharmacol. 2001;1(7):1229-1234.

Sun Y, Rao MS, Zigmond RE, Landis SC.

Regulation of vasoactive intestinal peptide expression in sympathetic neurons in culture and after axotomy: the role of cholinergic differentiation factor/leukemia inhibitory factor.

J Neurobiol. 1994;25(4):415-430.

Suzuki R, Fukai N, Nagashijma G, Asai JI, Itokawa H, Nagai M, Suzuki T, Fujimoto T.

Very early expression of vascular endothelial growth factor in brain oedema tissue associated with brain contusion.

Acta Neurochir Suppl. 2003;86:277-279.

Swartz KR. et al.

Interleukin-6 promotes post-traumatic healing in the central nervous system. Brain Res. 2001;896(1-2):86-95.

Tabakman R, Lecht S, Sephanova S, Arien-Zakay H, Lazarovici P.

Interactions between the cells of the immune and nervous system: neurotrophins as neuroprotection mediators in CNS injury.

Prog Brain Res. 2004;146:387-401.

Takahashi M, Hayashi S, Kakita A. et al.

Patients with temporal lobe epilepsy show an increase in brain-derived neutrophic factor protein and its correlation with neuropeptide Y.

Brain Res 1999;818(2):579-582.

Takeuchi A, Miyaishi O, Kiuchi K, Isobe K.

Macrophage colony-stimulating factor is expressed in neuron and microglia after focal brain injury. J Neurosci Res. 2001;65(1):38-44.

Tanaka A, Wakita U, Kambe N, Iwasaki T, Matsuda H.

An autocrine function of nerve growth factor for cell cycle regulation of vascular endothelial cells. Biochem Biophys Res Commun. 2004;313(4):1009-1014.

Tare RS, Oreffo RO, Sato K, Rauvala H, Clarke NM, Roach HI.

Effects of targeted overexpression of pleiotrophin on postnatal bone development. Biochem Biophys Res Commun. 2002;298(3):324-332.

Tasci A, Okay O, Gezici AR, Ergun R, Ergungor F.

Prognostic value of interleukin-1 beta levels after acute brain injury. Neurol Res. 2003;25(8):871-874.

Teoh N, Field J, Sutton J, Farrell G.

Dual role of tumor necrosis factor-alpha in hepatic ischemia-reperfusion injury: Studies in tumor necrosis factor-alpha gene knockout mice.

Hepatology. 2004;39(2):412-421.

Thelen M.

Dancing to the tune of chemokines. Nat Immunol. 2001;2:129-134.

Tobias CA, Shumsky JS, Shibata M, Tuszynski MH, Fischer I, Tessler A, Murray M. Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration.

Exp Neurol. 2003;184(1):97-113.

Tokumine J, Kakinohana O, Cizkova D, Smith DW, Marsala M.

Changes in spinal GDNF, BDNF, and NT-3 expression after transient spinal cord ischemia in the rat. J Neurosci Res. 2003;74(4):552-561.

Tokumine J, Sugahara K, Kakinohana O, Marsala M.

The spinal GDNF level is increased after transient spinal cord ischemia in the rat. Acta Neurochir Suppl. 2003;86:231-234.

Tomac AC, Agulnick AD, Haughey N, Chang CF, Zhang Y, Backman C, et al.

Effects of cerebral ischemia in mice deficient in Persephin. Proc Natl Acad Sci U S A. 2002;99(14):9521-9526.

Tsukamoto E, Hashimoto Y, Kanekura K, Niikura T, Aiso S, Nishimoto I.

Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells.

J Neurosci Res. 2003;73(5):627-636.

Tuszynski MH, Blesch A.

Nerve growth factor: from animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer's disease.

Prog Brain Res. 2004;146:441-449.

Tzeng SF, Huang HY.

Downregulation of inducible nitric oxide synthetase by neurotrophin-3 in microglia. J Cell Biochem. 2003;90(2):227-233.

Um JY, An NH, Kim HM.

TNF-alpha and TNF-beta gene polymorphisms in cerebral infarction. J Mol Neurosci. 2003;21(2):167-171.

Ure DR, Campenot RB.

Leukemia inhibitory factor and nerve growth factor are retrogradely transported and processed by cultured rat sympathetic neurons.

Dev Biol. 1994;162(2):339-347.

Venero IL, Hefti F.

Regionally specific induction of BDNF and trunkated Trk-B T1 receptors in the hippocampal formation after intraseptal injection of kainic acid.

Brain Res 1998;790(1-2):270-277.

Viglietto G, Dolci S, Bruni P, Baldassarre G, et al.

Glial cell line-derived neutrotrophic factor and neurturin can act as paracrine growth factors stimulating DNA synthesis of Ret-expressing spermatogonia.

Int J Oncol. 2000;16(4):689-694.

Villoslada P, Genain CP.

Role of nerve growth factor and other trophic factors in brain inflammation. Prog Brain Res. 2004;146:403-414.

Vincent VA, Robinson CC, Simsek D, Murphy GM.

Macrophage colony stimulating factor prevents NMDA-induced neuronal death in hippocampal organotypic cultures.

J Neurochem. 2002 Sep;82(6):1388-97.

Vincent VA, Selwood SP, Murphy GM Jr.

Proinflammatory effects of M-CSF and A beta in hippocampal organotypic cultures. Neurobiol Aging. 2002;23(3):349-362.

Wada K, Sugimori H, Bhide PG, Moskowitz MA, Finklestein SP.

Effect of basic fibroblast growth factor treatment on brain progenitor cells after permanent focal ischemia in rats.

Stroke. 2003;34(11):2722-2728.

Wada M, Kamata M, Aizu Y, Morita T, Hu J, Oyanagi K. Alteration of midkine expression in the ischemic brain of humans. J Neurol Sci. 2002;200(1-2):67-73.

Wang CY, Yang F, He XP, Je HS, Zhou JZ, Eckermann K, Kawamura D, Feng L, Shen L, Lu B. Regulation of neuromuscular synapse development by glial cell line-derived neurotrophic factor and neurturin.

J Biol Chem. 2002;277(12):10614-10625.

Wang R, Guo W, Ossipov MH, Vanderah TW, Porreca F, Lai J.

Glial cell line-derived neurotrophic factor normalizes neurochemical changes in injured dorsal root ganglion neurons and prevents the expression of experimental neuropathic pain.

Neuroscience. 2003;121(3):815-824.

Wang X, Ellison JA, Siren A-L. et al.

Prolonged expression of interferon-inducible protein-10 in ischemic cortex after permanent occlusion of middle cerebral artery in rat.

J Neurochem 1998;71:1194-1204.

Wang Y, Berezovska O, Fedoroff S.

Expression of colony stimulating factor-1 receptor (CSF-1R) by CNS neurons in mice. J Neurosci Res. 1999;57(5):616-632.

Wang Y, Pennock SD, Chen X, Kazlauskas A, Wang Z. PDGF receptor-mediated signal transduction from endosomes. J Biol Chem. 2003 Dec 2/ Epub.

Werner K, Bitsch A, Bunkowski S, Hemmerlein B, Bruck W.

The relative number of macrophages/microglia expressing macrophage colony-stimulating factor and its receptor decreases in multiple sclerosis lesions.

Glia. 2002 Oct;40(1):121-129.

Widenfalk J, Parvinen M, Lindqvist E, Olson L.

Neurturin, RET, GFRalpha-1 and GFRalpha-2, but not GFRalpha-3, mRNA are expressed in mice gonads.

Cell Tissue Res. 2000;299(3):409-415.

Wirth MJ, Brun A, Grabert J, Patz S, Wahle P.

Accelerated dendritic development of rat cortical pyramidal cells and interneurons after biolistic transfection with BDNF and NT4/5.

Development. 2003;130(23):5827-5838.

Xian CJ, Huang BR, Zhou XF.

Distribution of neurturin mRNA and immunoreactivity in the peripheral tissues of adult rats. Brain Res. 1999;835(2):247-258.

Xu B, Li S, Brown A, Gerlai R, Fahnestock M, Racine RJ.

EphA/ephrin-A interactions regulate epileptogenesis and activity-dependent axonal sprouting in adult rats.

Mol Cell Neurosci. 2003;24(4):984-999.

Yamagishi S, Matsumoto T, Yokomaku D, Hatanaka H, Shimoke K, Yamada M, Ikeuchi T. Comparison of inhibitory effects of brain-derived neurotrophic factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in cultured cerebellar granule neurons.

Brain Res Mol Brain Res. 2003;119(2):184-191.

Yamamoto M, Ito Y, Mitsuma N, Hattori N, Sobue G.

Pain-related differential expression of NGF, GDNF, IL-6, and their receptors in human vasculitic neuropathies.

Intern Med. 2003;42(11):1100-1103.

Yamashita S, Maeshima A, Kojima I, Nojima Y.

Activin A is a potent activator of renal interstitial fibroblasts. J Am Soc Nephrol. 2004;15(1):91-101.

Yan H, Newgreen DF, Young HM.

Developmental changes in neurite outgrowth responses of dorsal root and sympathetic ganglia to GDNF, neurturin, and artemin.

Dev Dyn. 2003;227(3):395-401.

Yang SZ, Zhang LM, Huang YL, Sun FY.

Distribution of Flk-1 and Flt-1 receptors in neonatal and adult rat brains. Anat Rec. 2003;274A(1):851-856.

Yang Z, Bagheri-Yarmand R, Wang RA, Adam L, Papadimitrakopoulou VV, Clayman GL, et al. The Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 (Iressa) Suppresses c-Src and Pak1 Pathways and Invasiveness of Human Cancer Cells.

Clin Cancer Res. 2004;10(2):658-667.

Yano H, Readhead C, Nakashima M, Ren SG, Melmed S.

Pituitary-directed leukemia inhibitory factor transgene causes Cushing's syndrome: neuro-immune- endocrine modulation of pituitary development.

Mol Endocrinol. 1998;12(11):1708-1720.

Yndestad A, Ueland T, Oie E, Florholmen G, Halvorsen B, Attramadal H, et al. Elevated Levels of Activin A in Heart Failure. Potential Role in Myocardial Remodeling. Circulation. 2004 Mar 1/ Epub.

Yoshimura S, Teramoto T, Whalen MJ, Irizarry MC, Takagi Y et al.

FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice.

J Clin Invest. 2003;112(8):1202-1210.

Yoshino J, Monkawa T, Tsuji M, Hayashi M, Saruta T.

Leukemia inhibitory factor is involved in tubular regeneration after experimental acute renal failure. J Am Soc Nephrol. 2003;14(12):3090-3101.

Zang da W, Cheema SS.

Leukemia inhibitory factor promotes recovery of locomotor function following spinal cord injury in the mouse.

J Neurotrauma. 2003;20(11):1215-1222.

Zhang ZG. et al.

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain. J Clin Invest. 2000;106(7):829-838.

Zhao L, Shang T, Wang YL, Tang S, Li H, Liu ZH.

[Study on the relationship between activin A, follistatin and preeclampsia] Zhonghua Fu Chan Ke Za Zhi. 2003;38(11):676-679.

Zaremba J, Losy J.

Interleukin-18 in acute ischaemic stroke patients. Neurol Sci. 2003;24(3):117-124.

Zheng H, Zhou S, You Z.

[The expression and distribution of ciliary neurotrophic factor in laryngeal nerve regeneration] Zhonghua Er Bi Yan Hou Ke Za Zhi. 1999;34(5):289-292.

Zhou Y, Zhai S, Yang W.

[The protective effects of ciliary neurotrophic factor on inner ear damage induced by intensive impulse noise]

Zhonghua Er Bi Yan Hou Ke Za Zhi. 1999;34(3):150-153.