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Abstract

In the past fifteen years, tremendous progress has been made in dog genomics. Several genetic aspects of cancer, heart disease, hip dysplasia, vision and hear­ing problems in dogs have been investigated and studied in detail.

Genome-wide associative studies have made it possible to identify several genes associated with diseases, morphological and behavioral traits. The dog genome contains an extraor­dinary amount of genetic variability that distinguishes the different dog breeds. As a consequence of the selective programs, applied using stringent breed standards, each dog breed represents, today, a population isolated from the others. The avail­ability of modern next generation sequencing (NGS) techniques and the identifica­tion of millions of single functional mutations (SNPs) has enabled us to obtain new and unknown detailed genomic data of the different breeds.

Keywords: canine genetics, canine genomics, bioinformatics, breeding, genetic diseases

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Source: Rutland Catrin (ed.). Canine Genetics, Health and Medicine. ITexLi,2021. — 165 p.. 2021

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