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LYSOSOME

It is a round, sac-like structure bounded by a single unit membrane composed of lipoprotein. Lysosomes are present in the cytoplasm as membrane-bound vesicular organelles. The lysosomes are produced by the Golgi apparatus.

These are found in abundance in phagocytic cells and secreted cells like WBC, kupffer’s cells, pancreatic cells, liver cells, etc. Structure. Lysosome shows polymorphism, i.e., dif­ferent morphological and physiological stages. It is filled with a granular matrix. It is rich in all types of hydrolytic enzymes called hydrolases.

2.6.1 Functions

• All enzymes (acid hydrolases) present in the lyso­some necessitate an acidic pH in order to carry out their functions, thus earning the name acid hydrolases.

• These acid hydrolases function efficiently at a pH level of 5. The lysosome’s membrane possesses an active H+ pump mechanism, which creates an acidic pH inside the lysosome’s lumen.

• Acid hydrolases have the capacity to break down various forms of macromolecules through hydrolysis.

2.7

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Source: Rana Tanmoy (ed.). Principles of Veterinary Animal Physiology. CRC Press,2026. — 290 p.. 2026

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