Infections Due to Histoplasma capsulatum var. duboisii
Infections due to H. capsulatum var. duboisii have been reported in baboons originating from West Africa after transfer to other locations (Gugnani and Muotoe-Okafor 1997). Secondary infections of the skin, subcutaneous tissues and the lymph nodes in the form of small papules and ulcerative granulomas have been reported in absence of involvement of the lungs and internal viscera.
The subspecies duboisii has not been isolated from livestock but is recognised in humans and in some wild mammals including bats (Nycteris hispida, Tadarida pumila), baboons (Papio cynocephalus) and aardvarks (Orycteropus afer), which could be markers of endemic foci (Chermette and Guillot 2010). The virulence of H. capsulatum var. duboisii seems to be lower than that of H. capsulatum var. capsulatum, which is consistent with the tendency of the variety duboisii to form mainly localised cutaneous and subcutaneous infections (Rippon 1988).5.5
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