References
1. Rothuizen J, DesmetVJ, van den Ingh T et al. Sampling and handling of liver tissue. In: WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases.
Edinburgh, Churchill Livingstone, 2006; 5—14.2. van den Ingh T, Cullen JM, Twedt DC et al. Morphological classification of biliary disorders of the canine and feline liver. In: WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases. Edinburgh, Churchill Livingstone, 2006; 61— 76.
3. Bosje JT, Bunch SE, van den Brom W et al. Plasma 14C-cholic acid clearance in healthy dogs and dogs with cholestasis or a congenital portosystemic shunt. Vet Rec 2005; 23: 109—112.
4. Cullen JM, van den Ingh T, Bunch SE et al. Morphological classification of circulatory disorders of the canine and feline liver. In: WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases. Edinburgh, Churchill Livingstone, 2006; 41—59.
5. Cullen JM, van den Ingh T, van Winkle T et al. Morphological classification of parenchymal disorders of the canine and feline liver; reversible hepatic injury and amyloidosis. In: WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases. Edinburgh, Churchill Livingstone, 2006; 77-84.
6. Rothuizen J, Meyer HP. History, physical examination, and signs of liver disease. In: Ettinger SJ, Feldman EC (eds.) Textbook of Veterinary Internal Medicine, 5th ed. Philadelphia, WB Saunders, 2000; 12721277.
7. Hughes D, King LG. The diagnosis and management of acute liver failure in dogs and cats. Vet Clin North Am Small Anim Pract 1995; 25: 437-460.
8. Hess PR, Bunch SE. Diagnostic approach to hepatobiliary disease. In: Bonagura JD (ed.) Kirks current veterinary therapy XIII. Philadelphia, WB Saunders, 2000; 659-664.
9.
Meyer HP, Rothuizen J, Ubbink GJ et al. Increasing incidence of hereditary intrahepatic portosystemic shunts in Irish Wolfhounds in the Netherlands (1984 to 1992). Vet Rec 1995; 136: 13-16.10. van den Ingh T, Van Winkle T, Cullen JM et al. Morphological classification of parenchymal disorders of the canine and feline liver; hepatocellular death, hepatitis and cirrhosis. In: WSAVA Standardsfor Clinical and Histological Diagnosis of Canine and Feline Liver Diseases. Edinburgh, Churchill Livingstone, 2006; 85-102.
11. Wijmenga C, Klomp LW. Molecular regulation of copper excretion in the liver. Proc Nutr Soc 2004; 63: 31-39.
12. Andersson M, Sevelius E. Breed, sex, and age distribution in dogs with chronic liver disease: a demographic study. J Small Anim Pract 1991; 32: 1-5.
13. van Straten G, Leegwater PA, de Vries M et al. Inherited congenital extrahepatic portosystemic shunts in Cairn Terriers.J Vet Intern Med 2005; 19: 321-324.
14. Ubbink GJ, van de Broek J, Meyer HP et al. Prediction of inherited portosystemic shunts in Irish Wolfhounds on the basis of pedigree analysis. Am J Vet Res 1998; 59: 1553-1556.
15. Sutherland RJ. Biochemical evaluation of the hepatobiliary system in dogs and cats. Vet Clin North Am Small Anim Pract 1989; 19: 899927.
16. Gerritzen-Bruning MJ, van den Ingh T, Rothuizen J. Diagnostic value of fasting plasma ammonia and bile acid concentrations in the identification of portosystemic shunting in dogs. J Vet Intern Med 2006; 20: 13-19.
17. Sterczer A, Meyer HP, Boswijk HC et al. Evaluation of ammonia measurements in dogs with two analyzers for use in veterinary practice. Vet Rec 1999; 144: 523-526.
18. Center SA. Serum bile acids in companion animal medicine. Vet Clin North Am Small Anim Pract 1993; 23: 625-657.
19. Trainor D, Center SA, Randolph F et al. Urine sulfated and nonsulfated bile acids as a diagnostic test for liver disease in cats. JVet Intern Med 2003; 17: 145-153.
20. Center SA, Manwarren T, Slater MR et al.
Evaluation of twelve- hour preprandial and two-hour postprandial serum bile acids concentrations for diagnosis of hepatobiliary disease in dogs. J Am Vet Med Assoc 1991; 199: 217-226.21. Gagne JM, Weiss DJ, Armstrong PJ. Histopathologic evaluation of feline inflammatory liver disease. Vet Pathol 1996; 33: 521-526.
22. Roth L, Meyer DJ. Interpretation of liver biopsies. Vet Clin North Am Small Anim Pract 1995; 25: 293-303.
23. Badylak SF. Coagulation disorders and liver disease. Vet Clin North Am Small Anim Pract 1988; 18: 87-92.
24. Bigge LA, Brown DJ, Penninck DG. Correlation between coagulation profile findings and bleeding complications after ultrasound- guided biopsies: 434 cases (1993-1996). JAm Anim Hosp Assoc 2001; 37: 228-233.
25. Dillon JF, Simpson KJ, Hayes PC. Liver biopsy bleeding time: an unpredictable event. J Gastroenterol Hepatol 1994; 9: 269-271.
26. Cole T, Center SA, Flood SN et al. Diagnostic comparison of needle biopsy and wedge biopsy specimens of the liver in dogs and cats. J Am Vet Med Assoc 2002; 220: 1483-1490.
27. Leveille R, Partington BP, Biller DS et al. Complications after ultrasound-guided biopsy of abdominal structures in dogs and cats: 246 cases (1984-1991). JAm Vet Med Assoc 1993; 203: 413-415.
28. Partington BP, Biller DS. Hepatic imaging with radiology and ultrasound. Vet Clin North Am Small Anim Pract 1995; 25: 305-335.
29. Pechman RD. The liver and spleen. In: Thrall DR (ed.) Textbook of Veterinary Diagnostic Radiology. Philadelphia, W.B. Saunders, 1986; 391-400.
30. Rothuizen J. Seeking global standardization on liver disease. J Small Anim Pract 2001; 42: 424-425.
31. Cole TL, Center SA, Flood SN et al. Diagnostic comparison of needle and wedge biopsy specimens of the liver in dogs and cats. J Am Vet Med Assoc 2002; 220: 1483-1490.
32. Stockhaus C, van den Ingh T, Rothuizen J et al. A multistep approach in the cytologic evaluation of liver biopsy samples of dogs with hepatic diseases.
Vet Pathol 2004; 41: 461-470.33. Cohen M, Bohling MW, Wright JC et al. Evaluation of sensitivity and specificity of cytologic examination: 269 cases (1999-2000). J Am Vet Med Assoc 2003; 222: 964-967.
34. Stockhaus C, Teske E, van den Ingh T et al. The influence of age on the cytology of the liver in healthy dogs. Vet Pathol 2002; 39: 154-158.
35. Cole TL, Center SA, Flood SN et al. Diagnostic comparison of needle and wedge biopsy specimens of the liver in dogs and cats. J Am Vet Med Assoc 2002; 220: 1483-1490.
36. Richter KP. Laparoscopy in dogs and cats. Vet Clin North Am Small Anim Pract 2001; 31: 707-727.
37. Hess PR, Bunch SE. Management of portal hypertension and its consequences. Vet Clin North Am Small Anim Pract 1995; 25: 461-483.
38. Johnson SE. Portal hypertension. Part I. Pathophysiology and clinical consequences. Comp Cont Edu Pract Vet 1987; 9: 741-748.
39. Johnson SE: Portal hypertension. Part II. Clinical assessment and treatment. Comp Cont Edu Pract Vet 1987; 9: 917-928.
40. Steyn PF, Wittum TE. Radiographic, epidemiologic, and clinical aspects of simultaneous pleural and peritoneal effusions in dogs and cats: 48 cases (1982-1991). JAm Vet Med Assoc 1993; 202: 307-312.
41. Rothuizen J, van den Brom WE. Bilirubin metabolism in canine hepatobiliary and haemolytic disease. Vet Q 1987; 9: 235-240.
42. Rothuizen J, van den Ingh T. Covalently protein-bound bilirubin conjugates in cholestatic disease of dogs. Am J Vet Res 1988; 49: 702-704.
43. Rothuizen J, van den Ingh T. Arterial and venous ammonia concentrations in the diagnosis of canine hepato-encephalopathy. ResVet Sci 1982;33: 17-21.
44. Maddison JE. Newest insights into hepatic encephalopathy. Eur J Comp Gastroenterol 2000; 5: 17-21.
45. Szatmari V, Rothuizen J, van den Ingh TS et al. Ultrasonographic findings in dogs with hyperammonemia: 90 cases (2000-2002). J Am Vet Med Assoc 2004; 224: 717-727.
46. Meyer HP, Rothuizen J, Tiemessen I et al. Transient metabolic hy- perammonaemia in young Irish Wolfhounds.
Vet Rec 1996; 138: 105-107.47. Rothuizen J, van den Ingh TS. Rectal ammonia tolerance test in the evaluation of portal circulation in dogs with liver disease. Res Vet Sci 1982; 33: 22-25.
48. Rothuizen J, Biewenga WJ, Mol JA. Chronic glucocorticoid excess and impaired osmoregulation of vasopressin release in dogs with hepatic encephalopathy. Domest Anim Endocrinol 1995; 12: 13-24.
49. Aronson LR, Drobatz K. Acetaminophen toxicosis in 17 cats. J Vet Emerg Crit Care 1996; 6: 65-69.
50. MacNaughton SM. Acetaminophen toxicosis in a Dalmatian. Can Vet J 2003; 44: 142-144.
51. Beasley VR. Toxicology of selected pesticides, drugs, and chemicals. Vet Clin North Am Small Anim Pract 1990; 20: 545-564.
52. Center SA, Elston TH, Rowland PH et al: Fulminant hepatic failure associated with oral administration of diazepam in 11 cats. J Am Vet Med Assoc 1996; 209: 618-625.
53. Hughs D, Moreau RE, Overall KL et al. Acute hepatic necrosis and liver failure associated with benzodiazepine therapy in six cats, 1986-1995. J Vet Emerg Crit Care 1996; 6: 13-20.
54. Harkin KR, Cowan LA, Andrews GA et al. Hepatotoxicity of stano- zolol in cats. J Am Vet Med Assoc 2000; 217: 681-684.
55. Kaufman AC, Greene CE. Increased alanine transaminase activity associated with tetracycline administration in a cat. J Am Vet Med Assoc 1993; 202: 628-630.
56. Boomkens SY, Penning LC, Egberink HF et al. Hepatitis with special reference to dogs. A review on the pathogenesis and infectious etiologies, including unpublished results of recent own studies. Vet Q 2004; 26: 107-114.
57. Mandigers PJ, van den Ingh TS, Spee B et al. Chronic hepatitis in Doberman pinschers. A review. Vet Q 2004; 26: 98-106.
58. Mandigers PJ, van den Ingh TS, Bode P et al. Association between liver copper concentration and subclinical hepatitis in Doberman Pinschers. J Vet Intern Med 2004; 18: 647-650.
59. Speeti M, Stahls A, Meri S et al. Upregulation of major histocompatibility complex class II antigens in hepatocytes in Doberman hepatitis.
Vet Immunol Immunopathol 2003; 96: 1-12. Erratum in: Vet Immunol Immunopathol 2005; 103: 295.60. Spee B, Mandigers PJ, Arends B et al. Differential expression of copper-associated and oxidative stress related proteins in a new variant of copper toxicosis in Doberman pinschers. Comp Hepatol 2005; 4 (3): 1-13.
61. Webb CB, Twedt DC, Meyer DJ. Copper-associated liver disease in Dalmatians: a review of 10 dogs (1998-2001). J Vet Intern Med 2002; 16:665-668.
62. Schultheiss PC, Bedwell CL, Hamar DW et al. Canine liver iron, copper, and zinc concentrations and association with histologic lesions. J Vet Diagn Invest 2002; 14: 396-402.
63. Kawamura M, Takahashi I, Kaneko JJ. Ultrastructural and kinetic studies of copper metabolism in Bedlington Terrier dogs. Vet Pathol 2002; 39: 747-750.
64. Favier RP, Spee B, Penning LC et al. Quantitative PCR method to detect a 13-kb deletion in the MURR1 gene associated with copper toxicosis and HIV-1 replication. Mamm Genome 2005; 16: 460-463.
65. Ubbink GJ, Van den Ingh TS, Yuzbasiyan-Gurkan V et al. Population dynamics of inherited copper toxicosis in Dutch Bedlington Terriers (1977-1997).J Vet Intern Med 2000; 14: 172-176.
66. Rothuizen J, Ubbink GJ, van Zon P et al. Diagnostic value of a microsatellite DNA marker for copper toxicosis in West-European Bedlington Terriers and incidence of the disease. Anim Genet 1999; 30: 190-194.
67. Bosje JT, van den Ingh TS, Fennema A et al. Copper-induced hepatitis in an Anatolian Shepherd dog. Vet Rec 2003; 152: 84-85
68. Mandigers PJ, van den Ingh TS, Bode P et al. Improvement in liver pathology after 4 months of D-penicillamine in 5 Doberman Pinschers with subclinical hepatitis. J Vet Intern Med 2005; 19: 4043.
69. van den Ingh TS, Rothuizen J. Lobular dissecting hepatitis in juvenile and young adult dogs. J Vet Intern Med 1994; 8: 217-220.
70. Wiedmeyer CE, Solter PE, Hoffmann WE. Alkaline phosphatase expression in tissues from glucocorticoid-treated dogs. Am J Vet Res 2002; 63: 1083-1088.
71. Wiedmeyer CE, Solter PE, Hoffmann WE. Kinetics of mRNA expression of alkaline phosphatase isoenzymes in hepatic tissues from glucocorticoid-treated dogs. Am J Vet Res 2002; 63: 10891095.
72. Hunt GB. Effect of breed on anatomy of portosystemic shunts resulting from congenital diseases in dogs and cats: a review of 242 cases. AustVet J 2004; 82: 746-749.
73. Winkler JT, Bohling MW, Tillson DM et al. Portosystemic shunts: diagnosis, prognosis, and treatment of 64 cases (1993-2001). J Am Anim Hosp Assoc 2003; 39: 169-185.
74. Washizu M, Katagi M, Washizu T et al. An evaluation of radiographic hepatic size in dogs with portosystemic shunt.J Vet Med Sci 2004; 66: 977-978.
75. Center SA, Baldwin BH, Erb H et al. Bile acid concentrations in the diagnosis of hepatobiliary disease in the cat.J Am Vet Med Assoc 1986; 189: 891-896.
76. Szatmari V, Rothuizen J, Voorhout G. Standard planes for ultrasonographic examination of the portal system in dogs.JAm Vet Med Assoc 2004; 224: 698-699, 713-716.
77. Szatmari V, Rothuizen J. Ultrasonographic identification and characterization of congenital portosystemic shunts and portal hypertensive disorders. In: WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases. Edinburgh, Churchill Livingstone, 2006; 15-40.
78. Lamb CR, Burton CA. Doppler ultrasonographic assessment of closure of the ductus venosus in neonatal Irish Wolfhounds. Vet Rec 2004; 155: 699-701.
79. Szatmari V, Rothuizen J, van Sluijs FJ et al. Ultrasonographic evaluation of partially attenuated congenital extrahepatic portosystemic shunts in 14 dogs. Vet Rec 2004; 155: 448-456.
80. d’Anjou MA, Penninck D, Cornejo L et al. Ultrasonographic diagnosis of portosystemic shunting in dogs and cats. Vet Radiol Ultrasound 2004; 45: 424-437.
81. Santilli RA, Gerboni G. Diagnostic imaging of congenital portosystemic shunts in dogs and cats: a review. Vet J 2003; 166: 7-18.
82. Havig M, Tobias KM. Outcome of ameroid constrictor occlusion of single congenital extrahepatic portosystemic shunts in cats: 12 cases (1993-2000).J Am Vet Med Assoc 2002; 220: 337-341.
83. Koblik PD, Hornof WJ. Transcolonic sodium pertechnetate Tc 99m scintigraphy for diagnosis of macrovascular portosystemic shunts in dogs, cats, and pot-bellied pigs: 176 cases (1988-1992). JAm Vet Med Assoc 1995; 207: 729-733.
84. Meyer HP, Rothuizen J, van Sluijs FJ et al. Progressive remission of portosystemic shunting in 23 dogs after partial closure of congenital portosystemic shunts. Vet Rec 1999; 144: 333-337.
85. Wolschrijn CF, Mahapokai W, Rothuizen J et al. Gauged attenuation of congenital portosystemic shunts: results in 160 dogs and 15 cats. Vet Q 2000; 22: 94-98.
86. Kummeling A,Van Sluijs FJ, Rothuizen J. Prognostic implications of the degree of shunt narrowing and of the portal vein diameter in dogs with congenital portosystemic shunts. Vet Surg 2004; 33: 17-24.
87. Levy JK, Bunch SE, Komtebedde J. Feline portosystemic vascular shunts. In: Bonagura JD, Kirk RW (eds.) Kirk’s Current Veterinary Therapy XII: Small Animal Practice. Philadelphia, WB Saunders, 1995;743-749.
88. Meyer HP, Chamuleau RA, Legemate DA et al. Effects of a branched-chain amino acid-enriched diet on chronic hepatic encephalopathy in dogs. Metab Brain Dis 1999; 14: 103-15.
89. Szatmari V, van den Ingh TS, Fenyves B et al. Portal hypertension in a dog due to circumscribed fibrosis of the wall of the extrahepatic portal vein. Vet Rec 2002; 150: 602-605.
90. Spee B, Penning LC, van den Ingh TS et al. Regenerative and fibrotic pathways in canine hepatic portosystemic shunt and portal vein hypoplasia, new models for clinical hepatocyte growth factor treatment. Comp Hepatol 2005; 4 (7): 1-11.
91. Zandvliet MM, Szatmari V, van den Ingh T et al. Acquired portosystemic shunting in 2 cats secondary to congenital hepatic fibrosis. J Vet Intern Med 2005; 19: 765-767.
92. van den Ingh TS, Rothuizen J, Meyer HP. Portal hypertension associated with primary hypoplasia of the hepatic portal vein in dogs. Vet Rec 1995; 137: 424-427.
93. Schermerhorn T, Center SA, Dykes NL et al. Characterization of hepatoportal microvascular dysplasia in a kindred of Cairn Terriers. J Vet Intern Med 1996; 10: 219-230.
94. Schaeffer IG, Kirpensteijn J, Wolvekamp WT et al. Hepatic arteriovenous fistulae and portal vein hypoplasia in a Labrador Retriever. J Small Anim Pract 2001; 42: 146-150.
95. Pike FS, Berg J, King NW et al. Gallbladder mucocele in dogs: 30 cases (2000-2002). JAm Vet Med Assoc 2004; 224: 1615-1622.
96. Gorlinger S, Rothuizen J, Bunch S et al. Congenital dilatation of the bile ducts (Caroli's disease) in young dogs.J Vet Intern Med 2003; 17: 28-32.
97. van den Ingh TS, Rothuizen J. Congenital cystic disease of the liver in seven dogs. J Comp Pathol 1985; 95: 405-414.
98. Schulze C, Rothuizen J, van Sluijs FJ et al. Extrahepatic biliary atresia in a Border Collie. J Small Anim Pract 2000; 41: 27-30.
99. van den Ingh TS, Rothuizen J, van den Brom WE. Extrahepatic cholestasis in the dog and the differentiation of extrahepatic and intrahepatic cholestasis. Vet Q 1986; 8: 150-157.
100. Boothe HW Boothe DM, Komkov A et al. Use of hepatobiliary scintigraphy in the diagnosis of extrahepatic biliary obstruction in dogs and cats: 25 cases (1982-1989). J Am Vet Med Assoc 1992; 201: 134-141.
101. Buote NJ, Webster CRL, Freeman L et al. Cholecystoenterostomy in cats - etiology and prognosis: 22 cases (1994-2003).JVet Intern Med 2004; 18: 246.
102. Liptak JM, Dernell WS, Monnet E et al. Massive hepatocellular carcinoma in dogs: 48 cases (1992-2002).JAm Vet Med Assoc 2004; 225: 1225-1230.
103. Carpenter JL, Andrews LK, Holzworth J. Tumors and tumor-like lesions. In: Holzworth J (ed.) Diseases of the Cat: Medicine and Surgery. Philadelphia, WB Saunders, 1987; 500-505.
104. Thamm DH. Hepatobiliary tumors. In: Withrow RG, MacEwen EG (eds.), Small Animal Clinical Oncology, 3rd edition. Philadelphia, WB Saunders, 2001; 327-334.
105. Charles JA, Cullen JM, van den Ingh T et al. Morphological classification of neoplastic disorders of the canine and feline liver. In: WSAVA Standardsfor Clinical and Histological Diagnosis of Canine and Feline Liver Diseases. Edinburgh, Churchill Livingstone, 2006; 117-124.
106. Biourge VC, Massat B, Groff JM et al. Effects of protein, lipid, or carbohydrate supplementation on hepatic lipid accumulation during rapid weight loss in obese cats. Am J Vet Res 1994; 55: 14061415.
107. Center SA, Crawford MA, Guida L et al. A retrospective study of 77 cats with severe hepatic lipidosis: 1975-1990. J Vet Intern Med 1993; 7: 349-359.
108. Armstrong PJ, Hardie EM. Percutaneous endoscopic gastrostomy: a retrospective study of 54 clinical cases in dogs and cats. J Vet Intern Med 1990; 4: 202-206.
109. Armstrong PJ, Hand MS, Frederick GS. Enteral nutrition by tube. Vet Clin North Am Small Anim Pract 1990; 20: 237-275.
110. Sparkes AH, Gruffyd-Jones TJ, Harbour DA. Feline infectious peritonitis: a review of clinicopathological changes in 65 cases and a critical assessment of their diagnostic value. Vet Rec 1991; 129: 209-212.
111. Broussard JD, Peterson ME, Fox PR. Changes in clinical and laboratory findings in cats with hyperthyroidism from 1983 to 1993. J Am Vet Med Assoc 195; 206: 302-305.
112. Weiss DJ, Gagne JM, Armstrong PJ. Relationship between feline inflammatory liver disease and inflammatory bowel disease, pancreatitis, and nephritis in cats.J Am Vet Med Assoc 1996; 209: 11141116.
113. Gagne JM, Armstrong PJ, Weiss DJ et al. Clinical features of inflammatory liver disease in cats: 41 cases (1983-1993). J Am Vet Med Assoc 1999; 214: 513-516.
114. Lucke VM, Davies JD. Progressive lymphocytic cholangitis in the cat. J Small Anim Pract 1984; 25: 249-260.
115. Boomkens SY, de Rave S, Pot RG et al. The role of Helicobacter spp. in the pathogenesis of primary biliary cirrhosis and primary sclerosing cholangitis. FEMS Immunol Med Microbiol 2005; 44: 221225.
116. Day MJ. Immunohistochemical characterization of the lesions of feline progressive lymphocytic cholangitis Zcholangiohepatitis. J Comp Path 1998; 119: 135-147.
117. Bielsa LM, Greiner EC. Liver flukes (Platynosomum concinnum) in cats.J Am Anim Hosp Assoc 1985; 21: 269-274.
118. Lewis DT, Malone JB, Taboada J et al. Cholangiohepatitis and choledochectasia associated with Amphimerus pseudofelineus in a cat. J Am Anim Hosp Assoc 1991; 27: 156-161.
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