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REFERENCES

The complete list of references can be found at www.expertconsult.com.

REFERENCES

Female Reproductive Disorders-Nonpathogenic Infertility

1. Hughes JP, Stabenfeldt GH, Evans JW: Clinical and endocrine aspects of the estrous cycle of the mare, Proc 18th Ann Conv Amer Assoc Eq Pract 18:119-148, 1972.

2. Pierson RA, Ginther OJ: Follicular population-dynamics during the estrous- cycle of the mare, Anim Reprod Sci 14:219, 1987.

3. Hughes JP, Stabenfeldt GH, Evans JW: The oestrous cycle of the mare, J Reprod Fertil Suppl (23):161, 1975.

4. Hughes JP, Stabenfeldt GH: Conception in a mare with an active corpus- luteum, J Am Vet Med Assoc 170:733, 1977.

5. Stevenson JS: Clinical reproductive physiology of the cow. In Youngquist RS, Trelfall WR, editors: Current Therapy in Large Animal Theriogenology, ed 2, Philadelphia, 1988, Saunders Elsevier, pp 258-270.

6. Reimers TJ, Smith RD, Newman SK: Management factors affecting reproductive performance of dairy cows in the northeastern United States, J Dairy Sci 68:963, 1985.

7. Viker SD, McGuire WJ, Wright JM, et al: Cow-calf association delays postpartum ovulation in mastectomized cows, Theriogenology 32:467, 1989.

8. Smith MC: Clinical reproductive physiology and endocrinology of does. In Youngquist RS, Trelfall WR, editors: Current Therapy in Large Animal Theriogenology, ed 2, Philadelphia, 1988, Saunders Elsevier, pp 535-537.

9. Tibary A, Anouassi A 1997. Theriogenology in Camelidae: anatomy, physiology, pathology and artificial breeding. Institut agronomique et veterinaire Hassan II, Rabat, Morocco.

Cystic Follicular Degeneration

1. Peter AT, Levine H, Drost M, et al: Compilation of classical and contem­porary terminology used to describe morphological aspects of ovarian dynamics in cattle, Theriogenology 71:1343, 2009.

2. Cole WJ, Bierschwal CJ, Youngquist RS, et al: Cystic ovarian disease in a herd of Holstein cows: a hereditary correlation, Theriogenology 25:813,

1986.

3. McEntee K: Reproductive pathology of domestic animals, San Diego, CA, 1990, Academic Press.

4. Donaldson LE, Hansel W, Vanvleck LD: Luteotropic properties of lutein­izing hormone and nature of oxytocin induced luteal inhibition in cattle, J Dairy Sci 48:331, 1965.

5. Ginther OJ, Wbody CO, Mahajan S, et al: Effect of oxytocin administration on the oestrous cycle of unilaterally hysterectomized heifers, J Reprod Fertil 14:225, 1967.

6. Ribadu AY, Ward WR, Dobson H: Comparative-evaluation of ovarian structures in cattle by palpation per rectum, ultrasonography and plasma progesterone concentration, Vet Rec 135:452, 1994.

7. Moreira ELT, Nascimento EFD, Chquiloff MAG: Morphologic alterations in the ovaries and the uterus of Capra hircus, l. 1: regressive alterations, Arq Esc Med Vet Univ Fed Bahia 14:25, 1991.

8. Medan MS, Watanabe G, Sasaki K, et al: Transrectal ultrasonic diagnosis of ovarian follicular cysts in goats and treatment with GnRH, Domest Anim Endocrinol 27:115, 2004.

9. Adams GP, Sumar J, Ginther OJ: Hemorrhagic ovarian follicles in llamas, Theriogenology 35:557, 1991.

10. Bravo PW, Stabenfeldt GH, Fowler ME, et al: Ovarian and endocrine patterns associated with reproductive abnormalities in llamas and alpacas, J Am Vet Med Assoc 202:268, 1993.

Ovarian Reserve and Anti-Mullerian Hormone

1. Ball BA, Conley AJ, MacLaughlin DT, et al: Expression of anti-Mullerian hormone (AMH) in equine granulosa-cell tumors and in normal equine ovaries, Theriogenology 70(6):968-977, 2008.

2. Claes A, Ball BA, Scoggin KE, et al: The interrelationship between anti- Mullerian hormone, ovarian follicular populations, and age in mares, Eq Vet J 47:537-541, 2015.

3. Claes A, Ball BA, Scoggin KE, et al: The influence of age, antral follicle count, and diestrous ovulation on estrous cycle characteristics of mares, Theriogenology 97:34-40, 2017.

4. de Vet A, Laven JSE, De Jong FH, et al: Anti-Mullerian hormone serum levels: a putative marker for ovarian aging, FertilSteril 77:357-362, 2002.

5. Durlinger ALL, Kramer P, Karels B, et al: Control of primordial follicle recruitment by anti-mullerian hormone in the mouse ovary, Endocrinology 140:5789-5796, 1999.

6. Goksedef BP, Idis N, Gorgen H, et al: The correlation of the antral follicle count and serum anti-mullerian hormone, J Turk-Ger Geynec Assoc 11:212-215, 2010.

7. Durlinger ALL, Visser JA, Themmen APN: Regulation of ovarian function: the role of anti-Mullerian hormone, Reproduction 124:601-609, 2002.

8. Durlinger ALL, Gruijters MJG, Kramer P, et al: Anti-Mullerian Hormone attenuates the effects of FSH on follicle development in the mouse ovary, Endocrinology 142:4891-4899, 2001.

9. Pankhurst MW: A putative role for anti-Mullerian hormone (AMH) in optimizing ovarian reserve expenditure, J Endocrinol 233:R1-R13, 2017.

10. Pellatt L, Rice S, Dilaver N, et al: Anti-Mullerian hormone reduces follicle sensitivity to follicle-stimulating hormone in human granulosa cells, Fertil Steril 96:1246-1251, 2011.

11. Scheffer GJ, Broekmans FJ, Dorland M, et al: Antral follicle counts by transvaginal ultrasonography are related to age in women with proven natural fertility, Fertil Steril 72:845-851, 1999.

Heat Stress

I. Hansen PJ: To be or not to be—determinants of embryonic survival following heat shock, Theriogenology 68:S40, 2007.

Seasonal Anestrus

1. Saltiel A, Calderon A, Garcia N, et al: Ovarian activity in the mare between latitude 15 degrees and 22 degrees, J Reprod Fertil Suppl 32:261, 1982.

2. Hughes JP, Stabenfeldt GH, Evans JW: Clinical and endocrine aspects of the estrous cycle of the mare, Proc 18th Ann Conv Amer Assoc Eq Pract 18:119-148, 1972.

3. Osborne VE: An analysis of the pattern of ovulation as it occurs in the annual reproductive cycle of the mare in Australia, Aust Vet J 42:149, 1966.

4. Van Niekerk CH: Patterns of the oestrus cycle of mares, J S Afr Vet Med Assoc 38:295, 1967.

5. Ginther OJ: Reproductive biology of the mare, Cross Plains, WI, 1992, Equiservices.

6. Palmer E, Driancourt MA: Photoperiodic stimulation of the winter anoestrous mare: what is a long day?, Les Colloques de PI.N.R.A. 6:67, 1981.

7. Burkhardt J: Transition from anoestrus in the mare and the effects of artificial lighting, J Agric Sci 37:64, 1947.

8. Murphy BA, Walsh CM, Woodward EM, et al: Blue light from individual light masks directed at a single eye advances the breeding sesason in mares, Eq Vet J 46:601-605, 2014.

9. Wespi B, Sieme H, Wedekind C, et al: Exposure to stallion accelerates the onset of mares’ cyclicity, Theriogenology 62(2):189-194, 2014.

10. Allen WR, Sanderson MW, Greenwood RE, et al: Induction of ovulation in anoestrous mares with a slow-release implant of a GnRH analogue (ICI 118 630), J Reprod Fertil Suppl 35:469, 1987.

II. Hyland JH, Wright PJ, Clarke IJ, et al: Infusion of gonadotrophin-releasing hormone (GnRH) induces ovulation and fertile oestrus in mares during seasonal anoestrus, J Reprod Fertil Suppl 35:211, 1987.

12. Fitzgerald BP, Affleck KJ, Loy RG: Investigation of the potential of lhrh or an agonist to induce ovulation in seasonally anoestrous mares with observations on the use of the agonist in problem acyclic mares, J Reprod Fertil Suppl 35:683, 1987.

13. Ginther OJ, Bergfelt DR: Effect of GnRH treatment during the anovulatory season on multiple ovulation rate and on follicular development during the ensuing pregnancy in mares, J Reprod Fertil 88:119, 1990.

14. McCue PM, Troedsson MH, Liu IK, et al: Follicular and endocrine responses of anoestrous mares to administration of native GnRH or a GnRH agonist, J Reprod Fertil Suppl 44:227, 1991.

15. Thorson JF, Allen CC, Amstalden M, et al: Pharmacologic application of native GnRH in the winter anovulatory mare, I: frequency of reversion to the anovulatory state following ovulation induction and cessation of treatment, Theriogenology 81:579-586, 2014.

16. Besognet B, Hansen BS, Daels PF: Induction of reproductive function in anestrous mares using a dopamine antagonist, Theriogenology 47:467, 1997.

17. Daels PF, Fatone S, Hansen BS, et al: Dopamine antagoinst-induced reproductive function in anoestrous mares: gonadotropin secretion and the effects of environmental cues, J Reprod Fertil Suppl 56:173, 2000.

18. McCue PM, Buchanan BR, Farquhar VJ, et al: Efficacy of domperidone on induction of ovulation in anestrous and transitional mares, Proc 45th Ann Conv Amer Assoc Eq Pract 45:217, 1999.

19. Squires EL, Stevens WB, McGlothlin DE, et al: Effect of an oral progestin on the estrous cycle and fertility of mares, J Anim Sci 49:729, 1979.

20. Taylor TB, Pemstein R, Loy RG: Control of ovulation in mares in the early breeding season with ovarian steroids and prostaglandin, J Reprod Fertil Suppl 32:219, 1982.

21. Webel SK, Franklin V, Harland B, et al: Fertility, ovulation and maturation of eggs in mares injected with hcg, J Reprod Fertil 51:337, 1977.

22. Roser JF, McCue PM, Troedsson MHT, et al: The induction of ovulation on seasonally anestrous mares under ambient light conditions using recombinant equine FSH (reFSH), Theriogenology 80:456, 2013.

23. Klump A, Aljarrah A, Sansinena M, et al: Follicular aspiration during transition to advance the onset of cyclicity, Pferdeheilkunde 19: 609, 2003.

24. Squires EL, Ginther OJ: Follicular and luteal development in pregnant mares, J Reprod Fertil Suppl 429, 1975.

25. Allen WR: Factors influencing pregnant mare serum gonadotrophin production, Nature 223:64, 1969.

26. Aguilar J, Luzuriaga I, Chavero VP, et al: Interruption of gestation and reuse of recipient mares in a commercial embryo transfer program, J Eq Vet Sci 32:397-422, 2012.

27. Steiner J, Antczak DF, Wolfsdorf K, et al: Persistent endometrial cups, Anim Reprod Sci 94:274, 2006.

28. Rathwell AC, Asbury AC, Hansen PJ, et al: Reproductive function of mares given pgf-2 alpha daily from day 42 of pregnancy, J Reprod Fertil Suppl 35:507, 1987.

29. Penzhorn BL, Bertschinger HJ, Coubrough RI: Reconception of mares following termination of pregnancy with prostaglandin f2 alpha before and after day 35 of pregnancy, Equine Vet J 18:215, 1987.

Lack of Behavioral Estrus (Silent Estrus)

1. Hughes JP, Stabenfeldt GH: Anestrus in the mare, Proc 23rd Ann Conv Amer Assoc Eq Pract 89-95, 1977.

Behavioral Nymphomania

1. Van Camp SD: Breeding soundness examination of the mare and common genital abnormalities encountered. In Morrow DA, editor: Current Therapy in Theriogenology, ed 2, Philadelphia, 1986, WB Saunders, pp 654-661.

2. McDonnell SM: Behavior problem: ovaries or not?, Proc 63rd Ann Conv Amer Assoc Eq Pract 131-134, 2017.

3. Hooper RN, Taylor TS, Varner DD, et al: Effects of bilateral ovariectomy via colpotomy in mares; 23 cases (1984-1990), J Am Vet Med Assoc 203:1043-1046, 1993.

Ruminants-Unobserved or Silent Estrus

1. Ball PJ: Milk progesterone profiles in relation to dairy herd fertility, Br Vet J 138:546, 1982.

2. A.I. Management manual. American Breeders Service, DeForest, WI; 1984..

3. O’Connor ML: Estrus detection. In Youngquist RS, Threlfall WR, editors: Current therapy in large animal theriogenology, ed 2, St. Louis, MO, 2007, WB Saunders, pp 270-278.

4. Van Horn hH, Wilcox CJ, DeLorenzo MA 1992. Large dairy herd management.

5. Romano JE, Larson JE: Accuracy of pregnancy specific protein-b test for early pregnancy diagnosis in dairy cattle, Theriogenology 74:932, 2010.

Infertility Caused by Abnormalities of the Female

Genital Organs-Abnormalities Caused by Problems With Sexual Differentiation

1. Makinen A, Katila T, Andersson M, et al: Two sterile stallions with xxy- syndrome, Equine Vet J 32:358, 2000.

2. Kubien EM, Pozor MA, Tischner M: Clinical, cytogenetic and endocrine evaluation of a horse with a 65,xxy karyotype, Equine Vet J 25:333, 1993.

3. Makinen A, Hasegawa T, Makila M, et al: Infertility in two mares with xy and xxx sex chromosomes, Equine Vet J 31:346, 1999.

4. Mayenco-Aguirre AM, Padilla JA, Flores JM, et al: Canine gonadal dysgenesis syndrome: a case of mosaicism (77,xo-78,xx), Vet Rec 145:582, 1999.

5. Dunn HO, Smiley D, Duncan JR, et al: Two equine true hermaphrodites with 64,xx∕64,xy and 63,xo∕64,xy chimerism, Cornell Vet 71:123, 1981.

6. Zhang T, Buoen LC, Seguin BE, et al: Diagnosis of freemartinism in cattle: the need for clinical and cytogenic evaluation, J Am Vet Med Assoc 204:1672, 1994.

7. Vainio S, Heikkila M, Kispert A, et al: Female development in mammals is regulated by wnt-4 signalling, Nature 397:405, 1999.

8. Meyers-Wallen VN, Hurtgen J, Schlafer D, et al: Sry-negative xx true hermaphroditism in a pasa fino horse, Equine Vet J 29:404, 1997.

9. Vaughan L, Schofield W, Ennis S: Sry-negative xx sex reversal iln a pony: a case report, Theriogenology 55:1051, 2001.

10. Rey R, Lukas-Croisier C, Lasala C, et al: Amh∕mis: what we know already about the gene, the protein and its regulation, Mol Cell Endocrinol 211:21, 2003.

11. Howden KJ: Androgen insensitivity syndrome in a thoroughbred mare (64, xy-testicular feminization), Can Vet J 45:501, 2004.

12. Vanderwall DK, Peyrot LM, Weber JA, et al 1989. Reproductive efficiency of the aged mare, pp 153-156. Proceedings of the Annual Meeting of the Society of Theriogenology.

13. Carnevale EM, Bergfelt DR, Ginther OJ: Aging effects on follicular activity and concentrations of fsh, lh, and progesterone in mares, Anim Reprod Sci 31:287, 1993.

14. Claes A, Ball BA, Scoggin K, et al: The interrelationship between anti- Mullarian hormone, ovarian flollicular populations and age in mares, Eq Vet J 47:537-541, 2015.

15. Carnevale EM, Ginther OJ: Reproductive function in old mares, Proc 40th Ann Conv Amer Assoc Eq Pract 15-16, 1994.

16. Carnevale EM, Bergfelt DR, Ginther OJ: Follicular activity and concentra­tions of fsh and lh associated with senescence in mares, Anim Reprod Sci 35:231, 1994.

17. Carnevale EM, Ginther OJ: Defective oocytes as a cause of subfertility in old mares. In Sharp DC, Bazer FW, editors: Equine Reproduction VI, Madison, WI, 1995, Society for the Study of Reproduction, pp 209-214.

18. Maher JM, Squires EL, Voss JL, et al: Effect of anabolic steroids on reproductive function of young mares, J Am Vet Med Assoc 183:519,

1983.

19. Skelton KV, Dowsett KF, McMeniman NP: Ovarian activity in fillies treated with anabolic steroids prior to the onset of puberty, J Reprod Fertil Suppl 44:351, 1991.

20. Daels PF, McCue PM, DeMoraes MJ, et al: Persistence of the luteal phase following ovulation during altrenogest treatment in mares, Theriogenology 46:799, 1996.

21. Johnson CA, Thompson DLJ, Kulinski KM, et al: Prolonged interovulatory interval and hormonal changes in mares following the use of ovuplant to hasten ovulation, J Equine Vet Sci 20:331, 2000.

22. McCue PM, Farquhar BS, Squires EL: Effect of the GnRH agonist deslorelin acetate on pituitary function and follicular development in the mare, Proc 46th Ann Conv Amer Assoc Eq Pract 355-356, 2000.

23. McCue PM, Niswender KD, Farquhar VJ: Induction of ovulation with deslorelin: options to facilitate implant removal, J Equine Vet Sci 22:54,

2002.

24. Beech J: Treatment of hypophysial adenomas, Compend Cont Educ Pract Vet 16:921, 1994.

25. Kolk JHVD: Equine Cushing’s disease, Eq Vet Educ 9:209, 1997.

26. Daels PF, Hughes JP: The abnormal estrous cycle. In McKinnon AO, Voss JL, editors: Equine reproduction, Philadelphia, 1993, Lea & Febiger, pp 144-160.

27. Asa CS, Ginther OJ: Glucocorticoid suppression of oestrus, follicles, LH and ovulation in the mare, J Reprod Fertil Suppl 32:247, 1982.

28. McNeill-Wiest DR, Thompson DL, Wiest JJ: Gonadotropin secretion in ovariectomized pony mares treated with dexamethasone or progesterone and subsequently with dihydrotestosterone, Domest Anim Endocrinol 5:149, 1988.

29. Pope NS, Sargent GF, Kesler DJ: The dexamethasone-induced suppression of androgen secretions suppressed estrous behavior in pony mares during the winter, J Equine Vet Sci 15:119, 1995.

30. Berghold P, Mostl E, Aurich C: Effects on reproductive status and manage­ment on cortisol secretion and fertility of oestrous mares, Anim Reprod Sci 102:276-285, 2007.

31. Willis D, Mason H, GillingSmith C, et al: Modulation by insulin of follicle­stimulating hormone and luteinizing hormone actions in human granulosa cells of normal and polycystic ovaries, J Clin Endocrinol Metab 81:302,

1996.

32. Vick MM, Sessions DR, Murphy BA, et al: Obesity is associated with altered metabolic and reproductive activity in the mare: effects of metformin on insulin sensitivity and reproductive cyclicity, Reprod Fert Dev 18:609,

2006.

33. Dybdal N: Pituitary pars intermedia dysfunction (equine Cushing’s-like disease). In Robinson NE, editor: Current Therapy in Equine Medicine, ed 4, Philadelphia, 1997, WB Saunders, pp 499-501.

34. McCue PM: Equine Cushing’s disease, Vet Clin North Am Equine Pract 18:533, 2002.

35. Burns TA: Effects of common equine endocrine diseases of reproduction, Vet Clin North Am Equine Pract 32:435-449, 2016.

36. Sessions-Bresnahan DR, Carnevale EM: The effect of equine metabolic syndrome on the ovarian follicular environment, J Anim Sci 92:1484-1493, 2014.

37. Sessions-Bresnahan DR, Schauer KL, Heuberger AL, et al: Effect of obesity on the preovulatory follicle and lipid fingerprint of equine oocytes, Biol Reprod 94:15, 2016. 1-12.

38. Fitzgerald BP, McManus CJ: Photoperiodic versus metabolic signals as determinants of seasonal anestrus in the mare, Biol Reprod 63:335-340, 2000.

39. Frank N, Geor RJ, Bailey SR, et al: Equine metabolic syndrome, J Vet Med 24:467-475, 2010.

40. Frank N: Vet Clin North Am Equine Pract 27(1):73-92, 2011. Burns TA.

2016. Effects of common equine endocrine diseases of reproduction. Vet. Clin. Eq. 32:435-449.

41. Rowan JA, Hague WM, Gao W, et al: Metformin versus insulin for the treatment of gestational diabetes, N Eng J Med 358:2003-2015, 2008.

Abnormally Enlarged Ovaries

1. Panciera RJ, Slusher SA, Hayes KEN: Ovarian teratoma and granulosa-cell tumor in 2 mares, Cornell Vet 81:43, 1991.

2. Meagher DM, Wheat JD, Hughes JP, et al: Granulosa cell tumors in mares—a review of 78 cases, Proc 23rd Ann Conv Amer Assoc Eq Pract 23:133, 1977.

3. Gift LJ, Gaughan EM, Schoning P: Metastatic granulosa-cell tumor in a mare, J Am Vet Med Assoc 200:1525, 1992.

4. Baumann LE, Sillerud CL, Spolar-Kilroy CR: Equine granulosa cell tumors: A review of fifteen cases, Minn Vet 25:52, 1985.

5. Gee EK, Dicken M, Archer RM, et al: Granulosa theca cell tumour in a pregnant mare: concentrations of inhibin and testosterone in serum before and after surgery, N Z Vet J 60:160, 2012.

6. McCue PM, Leblanc MM, Akita GY, et al: Granulosa-cell tumors in 2 cycling mares, J Equine Vet Sci 11:281, 1991.

7. Stabenfeldt GH, Hughes JP: Clinical aspects of reproductive endocrinology in the horse, Compend Contin Educ Pract Vet 9:678, 1987.

8. McCue PM: Equine granulosa cell tumors, Proc 38th Ann Conv Amer Assoc Eq Pract 38:587-593, 1992.

9. Bailey MT, Christman SA, Wheaton JE, et al: Inhibin localization in equine granulose-cell tumours and inhibin forms in tumour fluid, J Reprod Fertil Suppl 56:247, 2000.

10. Bailey MT, Troedsson MH, Wheato JE: Inhibin concentrations in mares with granulosa cell tumors, Theriogenology 57:1885, 2002.

11. Almeida J, Ball BA, Conley AJ, et al: Biological and clinical significance of anti-mullerian hormone determination in blood serum of the mare, Theriogenology 76:1393, 2011.

12. Ellenberger C, Bartmann CP, Hoppen HO, et al: Histomorphological and immunohistochemical characterization of equine granulosa cell tumours, J Comp Pathol 136:167, 2007.

13. Watson ED, Heald M, Tsigos A, et al: Plasma FSH inhibin a and inhibin isoforms containing pro- and -alphaC during winter anoestrus, spring transition and the breeding season in mares, Reproduction 123:535, 2002.

14. Nyack B, Johnson AD: A mammoth granulosa-cell tumor in a mare, Vet Med Sm Anim Clin 78:218, 1983.

15. Meyers PJ: Ovary and oviduct. In Kobluk CM, Ames TR, Geor RJ, editors: The horse, Philadelphia, PA, 1995, WB Saunders, pp 999-1004.

16. McKinnon AO: Ovarian abnormalities. In Rantanen NW, McKinnon AO, editors: Equine diagnostic ultrasonography, Baltimore, MD, 1997, Williams & Wilkins, pp 233-251.

17. Pierson RA: Folliculogenesis and ovulation. In McKinnon AO, Voss JL, editors: Equine reproduction, Philadelphia, PA, 1993, Lea & Feibiger, pp 161-171.

18. Kolling M, Allen W: Anovulatory haemorrhagic follicles (ahf’s) and ovulation failures in the mare, Reprod Domest Anim 41:308, 2006.

19. Lefranc AC, Allen WR: Incidence and morphology of anovulatory haemor­rhagic follicles in the mare, Pferdeheilkunde 19:611, 2003.

20. Riley SC, Gibson AH, Leask R, et al: Secretion of matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases into follicular fluid during follicle development in equine ovaries, Reproduction 121:553, 2001.

21. Ellenberger C, Muller K, Schoon HA, et al: Histological and immuno­histochemical characterization of equine anovulatory haemorrhagic follicles (ahfs), Reprod Domest Anim 44:395, 2009.

22. McCue PM, Squires EL: Persistent anovulatory follicles in the mare, Theriogenology 58:541, 2002.

23. Ginther OJ, Gastal EL, Gastal MO, et al: Conversion of a viable preovulatory follicle into a hemorrhagic anovulatory follicle in mares, Anim Reprod 3:29,

2006.

24. Hughes JP, Stabenfeldt GH, Evans JW: Estrous cycle and ovulation in the mare, J Am Vet Med Assoc 161:1367, 1972.

25. Daels PF, Hughes JP: The abnormal estrous cycle. In McKinnon AO, Voss JL, editors: Equine reproduction, Philadelphia, PA, 1993, Lea & Febiger, pp 144-160.

26. Betteridge KJ, Renard A, Goff AK: Uterine prostaglandin release relative to embryo collection, transfer procedures and maintenance of the corpus luteum, Equine Vet J Suppl 3:25, 1985.

27. Hughes JP, Stabenfeldt GH, Kindahl H, et al: Pyometra in the mare, J Reprod Fertil Suppl 321, 1979.

28. Ellsworth-Swihart M, Archbald LF, Ingraham RH, et al: Effect of phen­ylbutazone (pbz) on luteolysis in the mare induced by uterine biopsy, Theriogenology 23:381, 1985.

29. Vanderwall DK, Rasmussen DM, Carnahan KG, et al: Effect of administra­tion of oxytocin during diestrus on corpus luteum function and endometrial oxytocin receptor concentration in cycling mares, J Equine Vet Sci 32:536,

2012.

30. Stout TAE, Lamming GE, Allen WR: Oxytocin administration prolongs luteal function in cyclic mares, J Reprod Fertil 116:315, 1999.

31. Ginther OJ: Prolonged luteal activity in mares—a semantic quagmire, Equine Vet J 22:152, 1990.

32. Bergfelt DR, Pierson RA, Ginther OJ: Regression and resurgence of the cl following PGF(2 alpha) treatment 3 days after ovulation in mares, Theriogenology 65:1605, 2006.

33. Hurtgen JP, Whitmore HL: Effects of endometrial biopsy, uterine culture, and cervical dilatation on equine estrous-cycle, J Am Vet Med Assoc 173:97,

1978.

34. Douglas RH, Burns PJ, Hershman L: Phisiological and commercial parameters for producing progeny from subfertile mares by embryo transfer, Equine Vet J Suppl 3:111, 1985.

35. Daels PF, Stabenfeldt GH, Hughes JP, et al: Evaluation of progesterone deficiency as a cause of fetal death in mares with experimentally induced endotoxemia, Am J Vet Res 52:282, 1991.

36. Gunthle LM, McCue PM, Farquhar VJ, et al: Effect of prostaglandin administration post-ovulation on corpus luteum formation in the mare, Proc Ann Meeting Soc Theriogenol 139-140, 2000.

37. Troedsson MH, Ababneh MM, Ohlgren AF, et al: Effect of periovulatory prostaglandin f2alpha on pregnancy rates and luteal function in the mare, Theriogenology 55:1891, 2001.

38. Brendemuehl JP: Effect of oxytocin and cloprostenol on luteal formation, function and pregnancy rates in mares, Theriogenology 58:623, 2002.

39. Nie GJ, Johnson KE, Wenzel JGW, et al: Effect of periovulatory ecbolics on luteal function and fertility, Theriogenology 58:461, 2002.

40. Barber JA, Troedsson MH: Mummified fetus in a mare, J Am Vet Med Assoc 208:1438, 1996.

Ovarian Tumors-Granulosa Cell Tumor

1. Kitahara G, Nambo Y, Ali HE, et al: AntTmullerian hormone profiles as a novel biomarker to diagnose granulosa-theca cell tumors in cattle, J Reprod Develop 58:98, 2012.

Infertility Caused by Abnormalities of the

Female Tubular Genitalia

1. Saltiel A, Paramo R, Murcia C, et al: Pathologic findings in the oviducts of mares, Am J Vet Res 47:594, 1986.

2. Zent WW, Liu IKM, Spirito MA Oviduct flushing as a treatment for infertility in the mare, Proc Third Equine Embryo Transfer Meeting 47-48,

1992.

3. Allen WE, Kessy BM, Noakes DE: Evaluation of uterine tube function in pony mares, Vet Rec 105:364, 1979.

4. Arnold CE, Love CC: Laparoscopic evaluation of oviductal patency in the standing mare, Anim Reprod Sci 121S:S86, 2010.

5. Kelly EF, Renton JP, Munro CD: Assessment of oviduct potency in the cow, Vet Rec 108:357, 1981.

6. Eilts BE, Seguin BE, Fahning ML: Evaluation of oviduct patency in donor cows using the phenosulfonphthalein oviduct patency test, Theriogenology 17:87, 1982.

7. Coe PH: Uterine flush as therapy for repeat breeder cows, Agri-Practice 5:29-37, 1984.

Uterine Abnormalities

1. Burns SJ, Judge NG, Martin JE, et al: Management of retained placenta in mares, Proc 23rd Ann Conv Amer Assoc Eq Pract 23:381-390, 1977.

2. Paisley LG, Mickelsen WD, Anderson PB: Mechanisms and therapy for retained fetal membranes and uterine infections of cows: a review, The- riogenology 25:353, 1986.

3. Beagley JC, Whitman KJ, Baptiste KE, et al: Physiology and treatment of retained fetal membranes in cattle, J Vet Intern Med 24:261, 2010.

4. Miller BJ, Lodge JR: Postpartum oxytocin treatment for prevention of retained placentas, Theriogenology 22:385, 1984.

5. Hickey GJ, White ME, Wickenden RP, et al: Effects of oxytocin on placental retention following dystocia, Vet Rec 114:189, 1984.

6. Pimentel S, Evans G, Wagner WC: Placental synthesis of estrogens at parturition and during placental retention in the cow, Theriogenology 28:755,

1987.

7. Studer E, Holtan A: Treatment of retained placentas in dairy cattle with prostaglandin, Bovine Pract 21:159, 1986.

8. Burton MJ, Herschler RC, Dziuk HE, et al: Effect of fenprostalene on postpartum myometrial activity in dairy cows with normal or delayed placental expulsion, Br Vet J 143:549, 1987.

9. Horta AE, Chassagne M, Brochart M: Prostaglandin f2 alpha and prostacyclin imbalance in cows with place13,14ntal retention: new findings, Ann Rech Vet 17:395, 1986.

10. Stevens RD, Dinsmore RP: Treatment of dairy cows at parturition with prostaglandin f2 alpha or oxytocin for prevention of retained fetal membranes, J Am Vet Med Assoc 211:1280, 1997.

11. Moller K, Newling PE, Robson HJ, et al: Retained foetal membranes in dairy herds in the Huntly district, N Z Vet J 15:111, 1967.

12. Ball L, Olson JD, Mortimer RG: Bacteriology of the postpartum uterus, Proc Meeting Soc Theriogenol 164-169, 1984.

13. Drillich M, Arlt S, Kersting S, et al: Ceftiofur derivatives in serum, uterine tissues, cotyledons, and lochia after fetal membrane retention, J Dairy Sci 89:3431, 2006.

14. Drillich M, Mahlstedt M, Reichert U, et al: Strategies to improve the therapy of retained fetal membranes in dairy cows, J Dairy Sci 89:627,

2006.

15. Eiler H, Fectau KA: Retained placenta. In Youngquist RS, Threlfall WR, editors: Current Therapy in Large Animal Theriogenology, St. Louis, MO,

2007, Saunders Elsevier, pp 353-381.

16. Traub-Dargatz JL, Salman MD, Voss JL: Medical problems of adult horses, as ranked by equine practitioners, J Am Vet Med Assoc 198:1745, 1991.

17. Pascoe RR: Observations on the length and angle of declination of the vulva and its relation to fertility in the mare, J Reprod Fertil Suppl 27:299,

1979.

18. Troedsson MHT, Liu IKM, Ing M, et al: Uterine response to semen deposition in the mare, Proc Ann Meeting Soc Theriogenol 130-135, 1995.

19. Zent WW, Troedsson MHT: Postbreeding uterine fluid accumulation in a normal population of Thoroughbred mares: a field study, Proc 44th Ann Conv Amer Assoc Eq Pract 44:64-65, 1998.

20. Watson ED, Barbacini S, Berrocal B, et al: Effect of insemination time of frozen semen on incidence of uterine fluid in mares, Theriogenology 56:123, 2001.

21. Barbacini S, Necchi D, Zavaglia G, et al: Retrospective study on the incidence of postinsemination uterine fluid in mares inseminated with frozen/thawed semen, J Equine Vet Sci 23:493, 2003.

22. Hughes JP, Loy RG: Investigations on the effect of intrauterine inoculation of Streptococcus Zooepidemicus in the mare, Proc 15th Ann Conv Amer Assoc Eq Pract 15:289-292, 1969.

23. Peterson FB, McFeely RA, David JSE: Studies on the pathogenesis of endometritis in the mare, Proc 15th Ann Conv Amer Assoc Eq Pract 279-285, 1969.

24. Neely DP, Kindahl H, Stabenfeldt GH, et al: Prostaglandin release patterns in the mare: Physiological, pathophysiological, and therapeutic responses, J Reprod Fertil Suppl 27:181, 1979.

25. Asbury AC, Halliwell RE, Foster GW, et al: Immunoglobulins in uterine secretions of mares with differing resistance to endometritis, Theriogenology 14:299, 1980.

26. Mitchell G, Liu IK, Perryman LE, et al: Preferential production and secretion of immunoglobulins by the equine endometrium—a mucosal immune system, J Reprod Fertil Suppl 32:161, 1982.

27. Troedsson MH, Liu IK, Thurmond M: Immunoglobulin (igg and iga) and complement (c3) concentrations in uterine secretion following an intrauterine challenge of Streptococcus zooepidemicus in mares suscep­tible to versus resistant to chronic uterine infection, Biol Reprod 49:502,

1993.

28. Waelchli RO, Winder NC: Mononuclear cell infiltration of the equine endometrium: immunohistochemical studies, Equine Vet J 23:470, 1991.

29. Williamson P, Dunning A, O’Connor J, et al: Immunoglobulin levels, protein concentrations and alkaline phosphatase activity in uterine flushings from mares with endometritis, Theriogenology 19:441, 1983.

30. Pycock JF: Assessment of oxytocin and intrauterine antibiotics on intrauterine fluid and pregnancy rates in the mare, Proc 40th Ann Conv Amer Assoc Eq Pract 40:19-20, 1994.

31. Lees P, Dawson J, Sedgwick AD: Eicosanoids and equine leucocyte locomotion in vitro, Equine Vet J 18:493, 1986.

32. Pycock JF, Allen WE: Inflammatory components in uterine fluid from mares with experimentally induced bacterial endometritis, Equine Vet J 22:422, 1990.

33. Watson ED, Stokes CR, Bourne FJ: Cellular and humoral defence mechanisms in mares susceptible and resistant to persistent endometritis, Vet Immunol Immunopathol 16:107, 1987.

34. Watson ED, Stokes CR, Bourne FJ: Influence of arachidonic acid metabolites in vitro and in uterine washings on migration of equine neutrophils under agarose, Res Vet Sci 43:203, 1987.

35. Troedsson MH, Liu IK, Thurmond M: Function of uterine and blood- derived polymorphonuclear neutrophils in mares susceptible and resistant to chronic uterine infection: phagocytosis and chemotaxis, Biol Reprod 49:507, 1993.

36. Christoffersen M, Wbodward E, Bojesen AM, et al: Inflammatory responses to induced infectious endometritis in mares resistant or susceptible to persistent endometritis, BMC Vet Res 8:41, 2012.

37. Woodward E, Christoffersen M, Campos J, et al: Endometrial inflammatory markers of the early innate immune response in mares susceptible or resistant to persistent breeding induced endometritis, Reproduction 145:289,

2013.

38. Troedsson MH, Liu IK: Uterine clearance of non-antigenic markers (51cr) in response to a bacterial challenge in mares potentially susceptible and resistant to chronic uterine infections, J Reprod Fertil Suppl 44:283, 1991.

39. LeBlanc MM, Neuwirth L, Asbury AC, et al: Scintigraphic measurement of uterine clearance in normal mares and mares with recurrent endometritis, Equine Vet J 26:109, 1994.

40. Troedsson MH, Liu IK, Ing M, et al: Multiple site electromyography recordings of uterine activity following an intrauterine bacterial challenge in mares susceptible and resistant to chronic uterine infection, J Reprod Fertil 99:307, 1993.

41. Alghamdi AS, Foster DN, Carlson CS, et al: Nitric oxide levels and nitric oxide synthase expression in uterine samples from mares susceptible and resistant to persistent breeding-induced endometritis, Am J Reprod Immunol 53:230, 2005.

42. Brewer RA: Contagious equine metritis: a review/summary, Vet Bull 53:881,

1983.

43. Powell DG: Contagious equine metritis. In Morrow DA, editor: Current Therapy in Theriogenology: Diagnosis, Treatment and Prevention of Reproductive Diseases in Animals, Philadelphia, PA, 1986, WB Saunders, pp 786-792.

44. Asbury AC: Infectious and immunologic considerations in mare infertility, Compend Contin Educ Pract Vet 9:585, 1987.

45. Troedsson MH: Uterine clearance and resistance to persistent endometritis in the mare, Theriogenology 52:461, 1999.

46. LeBlanc MM: The chronically infertile mare, Proc 54th Ann Conv Amer Assoc Eq Pract 54:391-407, 2008.

47. Maurice NM, Bedi B, Sadikot RT: Pseudomonas aeruginosa biofilms: Host response and clinical implications in lung infections, Am J Respir Cell Mol Biol 428-429, 2018.

48. Ferris RA, McCue PM, Borlee GI, et al: Model of chronic equine endometritis involving a Pseudomonas aeruginosa biofilm, Infect Immun 85(12):2017.

49. Petersen MR, Nielsen JM, Lehn-Jensen H, et al: Streptococcus equi subspecies Zooepidemicus resides deep in the chronically infected endometrium of mares, Proc Ann Conv Soc Theriogenol 161-167, 2009.

50. Kotilainen T, Huhtinen M, Katila T: Sperm-induced leukocytosis in the equine uterus, Theriogenology 41:629, 1994.

51. Troedsson MHT, Steiger BN, Ibrahim NM, et al: Mechanisms of sperm-induced endometritis in the mare (abstract), Biol Reprod 52:307, 1995.

52. Troedsson MH, Liu IK, Crabo BG: Sperm transport and survival in the mare: a review, Theriogenology 50:807, 1998.

53. Brinsko SP, Varner DD, Blanchard TL: The effect of uterine lavage performed four hours post-insemination on pregnancy rates in mares, Theriogenology 35:1111, 1991.

54. Scott MA, Liu IKM, Overstreet JW: Sperm transport to the oviducts: abnormalities and their clinical implications, Proc 41st Ann Conv Amer Assoc Eq Pract 41:1-2, 1995.

55. Katila T, Sankari S, Makela O: Transport of spermatoZoa in the reproductive tracts of mares, J Reprod Fertil Suppl 56:571, 2000.

56. Troedsson MHT, Lee CS, Franklin RD, et al: The role of seminal plasma in post-breeding uterine inflammation, J Reprod Fertil Suppl 56:341, 2000.

57. Troedsson MH, Loset K, Alghamdi AM, et al: Interaction between equine semen and the endometrium: the inflammatory response to semen, Anim Reprod Sci 68:273, 2001.

58. Alghamdi AS, Foster DN, Troedsson MH: Equine seminal plasma reduces sperm binding to polymorphonuclear neutrophils (pmns) and improves the fertility of fresh semen inseminated into inflamed uteri, Reproduction 127:593, 2004.

59. Troedsson MHT, Desvousges AL, Hansen PJ, et al: Equine seminal plasma proteins protect live spermatoZoa from pmn-binding and phagocytosis, while providing a mechanism for selective sperm elimination of apoptotic and dead spermatoZoa, Anim Reprod Sci 94:60, 2006.

60. Doty A, Buhi WC, Benson S, et al: Equine crisp3 modulates interaction between spermatoZoa and polymorphonuclear neutrophils, Biol Reprod 85:157, 2011.

61. LeBlanc MM, Asbury AC, Lyle SK: Uterine clearance mechanisms during the early postovulatory period in mares, Am J Vet Res 50:864, 1989.

62. Marth CD, Firestone SM, Hanlon D, et al: Innate immune genes in persistent mating-induced endometritis in horses, Reprod Fert Dev 2017, doi:10.1071/RD17157.

63. Blanchard TL, Garcia MC, Hurtgen JP, et al: Comparison of two techniques for obtaining endometrial bacteriologic cultures in the mare, Theriogenology 16:85, 1981.

64. Ball BA, Shin SJ, Patten VH, et al: Use of a low-volume uterine flush for microbiologic and cytologic examination of the mare’s endometrium, Theriogenology 29:1269, 1988.

65. LeBlanc MM, Magsig J, Stromberg AJ: Use of a low-volume uterine flush for diagnosing endometritis in chronically infertile mares, Theriogenol- ogy 68:403, 2007.

66. Nielsen JM: Endometritis in the mare: a diagnostic study comparing cultures from swab and biopsy, Theriogenology 64:510, 2005.

67. Riddle WT, LeBlanc MM, Stromberg AJ: Relationships between uterine culture, cytology and pregnancy rates in a Thoroughbred practice, Theriogenology 68:395, 2007.

68. Troedsson MH, deMoraes MJ, Liu IK: Correlations between histologic endometrial lesions in mares and clinical response to intrauterine exposure with Streptococcus zooepidemicus, Am J Vet Res 54:570, 1993.

69. Woodward EM, Christoffersen M, Campos J, et al: Susceptibility to persistent breeding-induced endometritis in the mare: relationship to endometrial biopsy score and age, and variations between seasons, Theriogenology 78:495, 2012.

70. Pycock JF, Newcombe JR: The relationship between intraluminal uterine fluid, endometritis, and pregnancy rate in the mare, Eq Pract 18:19, 1996.

71. Troedsson MHT: Therapeutic considerations for mating-induced endometritis, Pferdeheilkunde 13:516, 1997.

72. Couto MA, Hughes JP: Sexually transmitted (venereal) diseases of horses. In McKinnon AO, Voss JL, editors: Equine Reproduction, Philadelphia, PA, 1993, Lea & Febiger, pp 845-854.

73. Swerczek TW: Contagious equine metritis—outbreak of the disease in Kentucky and laboratory methods for diagnosing the disease, J Reprod Fertil Suppl 361, 1979.

74. Kenney RM, Bergman RV, Cooper WL, et al: Minimal contamination techniques for breeding mares: technique and preliminary findings, Proc 21st Ann Conv Amer Assoc Eq Pract 21:327-336, 1975.

75. Brown MP, Embertson RM, Gronwall RR, et al: Amikacin sulfate in mares: pharmacokinetics and body fluid and endometrial concentrations after repeated intramuscular administration, Am J Vet Res 45:1610, 1984.

76. Hess MB, Parker NA, Purswell BJ, et al: Use of lufenuron as a treatment for fungal endometritis in four mares, J Am Vet Med Assoc 221:266, 2002.

77. Gores-Lindholm AR, leBlanc MM, Causey R, et al: Relationships between intrauterine infusion of N-acetylcysteine, equine endometrial pathology, neutrophil function, post-breeding therapy, and reproductive performance, Theriogenology 80:218-227, 2013.

78. Petersen MR, Skive B, Christoffersen M, et al: Activation of persistent Streptococcus equi subspecies zooepidemicus in mares with subclinical endometritis, Vet Microbiol 179:119-125, 2015.

79. Ferris RA, McCue PM, Borlee GI, et al: In vitro efficacy of nonantibiotic treatments of biofilm disruption of gram-negative pathogens and an in vivo model of infectious endometritis utilizing isolates from the equine uterus, J Clin Microb 54:631-639, 2016.

80. Zuin R, Palamidese A, Negrin R, et al: High dose N-acetylcysteine in patients with exacerbation of chronic obstructive pulmonary disease, Clin Drug Investig 25:401-408, 2005.

81. LeBlanc MM, McKinnon AO: Breeding the problem mare. In McKinnon AO, Squires EL, Vaala WE, et al, editors: Equine Reproduction, 2nd ed, West Sussex, UK, 2011, Wiley Blackwell, p 2620.

82. Witte TS, Melkus E, Walter I, et al: Effects of oral treatment with N-acetylcysteine on the viscosity of intrauterine mucus and endometrial function in estrus mares, Theriogenology 78(6):1199-1208, 2012.

83. Lyle SK, LeBlanc MM, Staepfli SA, et al: How to use buffered chelator solution for mares with chronic endometritis, Proceedings AAEP 57:16-18,

2011.

84. Christoffersen M, Woodward EM, Bojesen AM, et al: Effect of immu­nomodulatory therapy on the endometrial inflammatory response to induced infectious endometritis in susceptible mares, Theriogenology 78:991-1004, 2012.

85. Fumoso E, Giguere S, Wade J, et al: Endometrial IL-beta, IL-6 and TNF-alpha mRNA expression in mares resistant or susceptible to post­breeding endometritis. Effects of estrous cycle, artificial insemination and immunomodulation, Vet Immunol Immunopathol 96:31-41,

2003.

86. Rogan D, Fumoso E, Rodrigez E, et al: Use of mycobacterial cell wall extract (MCWE) in susceptible mares to clear experimentally induced endometritis with Streptococcus zooepidemicus, J Eq Vet Sci 27:112-117,

2007.

87. Rohrbach B, Sheerin P, Steiner J, et al: Use of Propionibacterium acnes as adjunct therapy in treatment of persistent endometritis in the broodmare, Anim Reprod Sci 94:259, 2006.

88. Asbury AC: Uterine defense mechanisms in the mare: The use of intrauterine plasma in the management of endometritis, Theriogenology 21:387, 1984.

89. Zerbe H, Castilho LFF, Engelke F, et al: Isolation and cryopreservation of functionally competent equine leukocytes, J Vet Med 50:179-184, 2003.

90. Mattos RC, Castillo LFF, Malschitzky E, et al: Treatment of endometritis of experimentally infected mares. I. Effect of lavage, plasma and leukocytes on uterine bacterial challenge, Arq Fac Vet. - UFRGS 27:49-60, 1999.

91. Neves AP, Keller A, Rodrigues-Trein C, et al: Use of leukocytes as treatment for endometritis in mares experimentally infected with Streptococcus zooepidemicus, Anim Reprod Sci 97:314-322, 2007.

92. Troedsson MH, Scott MA, Liu IK: Comparative treatment of mares susceptible to chronic uterine infection, Am J Vet Res 56:468, 1995.

93. LeBlanc MM, Neuwirth L, Mauragis D, et al: Oxytocin enhances clearance of radiocolloid from the uterine lumen of reproductively normal mares and mares susceptible to endometritis, Eq Vet J 26:279-282, 1994.

94. Troedsson MHT, Scott M, Liu IKM: Comparative treatment of mares susceptible to chronic uterine infection, Am J Vet Res 56(4):468-472, 1995.

95. Troedsson MHT, Liu IKM, Ing M, et al: Smooth muscle electrical activity in the oviduct and the effect of oxytocin, PGF2a and PGE2 on the myometrium and oviduct of the cycling mare. In Sharp DC, Bazer FW, editors: Biol Repr Mono 1. Equine Reproduction VI, 2005, pp 439-452.

96. Campbell MLH, England GCW: A comparison of the ecbolic efficacy of intravenous and intrauterine oxytocin treatments, Theriogenology 58:473-477, 2002.

97. Madill S, Troedsson MHT, Santschi EM, et al: Dose-response effect on intramuscular oxytocin treatment on myometrial contraction of repro- ductively normal mares during estrus, Theriogenology 58:479-481, 2002.

98. Schramme AR, Pinto CRF, Davies J, et al: Pharmacokinetics of carbetocin, a long-acting analogue, following intravenous administration in horses, Eq Vet J 40:658-661, 2008.

99. Deleted in review.

100. Madill S, Troedsson MHT, Alexander SL, et al: Simultaneous recording of pituitary oxytocin secretion and myometrial activity in estrous mares exposed to various breeding stimuli, J Repr Fert 56:351-361, 2000.

101. Lyle SK, Durand R, Taylor VP, et al: Effect of contextually congruent stallion vocalization playback on intrauterine pressure in the mare, J Eq Vet Sci 34:131, 2014.

102. Bucca S, Carli A, Buckley T, et al: The use of dexamethasone administered to mares at breeding time in the modulation of persistent mating induced endometritis, Theriogenology 70:1093, 2008.

103. Vandaele H, Daels P, Piepers S, et al: The effect of post-insemination dexamethasone treatment on pregnancy rates in mares, Proc, The Havemeyer Foundation: The Chronically Infertile Mare 43-44, 2008.

104. Dell'Aqua JA, Papa FO, Lopes MD, et al: Fertility rates with equine frozen semen after modulation of inflammatory uterine response, Proc 15th Int Congr Anim Reprod 15:391, 2004.

105. Woodward EM, Christoffersen M, Horohov D, et al: The effect of treatment with immune modulators on endometrial cytokine expression in mares susceptible to persistent breeding induced endometritis, Eq Vet J 47:235-239, 2014.

106. Woodward E, Christoffersen M, Horohov D, et al: The effect of immune modulators on endometrial cytokine expression in mares susceptible to persistent breeding induced endometritis, Reprod Domest Anim 47:560,

2012.

107. Rojer H, Aurich C: Treatment of persistent mating-induced endometritis in mares with the non-steroid anti-inflammatory drug vedaprofen, Reprod Dom Anim 45:458-460, 2010.

108. Fumuso EA, Aguilar J, Giguere S, et al: Immune parameters in mares resistant and susceptible to persistent post-breeding endometritis: effects of immunomodulation, Vet Immunol Immunopathol 118:30, 2007.

109. Reghini MFS, Ramires Neto C, Sagabinazzi LG, et al: Inflammatory response in chronic degenerative endometritis mares treated with platelet­rich plasma, Theriogenology 86:516-522, 2016.

110. Segabinazzi LG, Friso AM, Correal SB, et al: Uterine clinical findings, fertility rate, leukocyte migration, and COX-2 protein levels in the endometrial tissue of susceptible mares treated with platelet-rich plasma before and after AI, Theriogenology 104:120-126, 2017.

111. Metcalf ES, Scoggin K, Troedsson MHT: The effect of platelet-rich plasma on endometrial pro-inflammatory cytokines in susceptible mares following semen deposition, J Eq Vet Sci 32:498, 2012.

112. Fedorka CE, Scoggin KE, Boakari Y, et al: Exogenous lactoferrin as a therapeutic for the treatment of persistent breeding-induced endometritis (PBIE), Theriogenology 114:63-69, 2018.

113. Allen WR: Proceedings of the John P. Hughes international workshop on equine endometritis, Equine Vet J 25:184, 1993.

114. Oikawa M, Katayama Y, Yoshihara T, et al: Microscopical characteristics of uterine wall arteries in barren aged mares, J Comp Pathol 108:411, 1993.

115. Ley WB, Bowen JM, Sponenberg DP, et al: Dimethyl sulfoxide intrauterine therapy in the mare: effects upon endometrial histological features and biopsy classification, Theriogenology 32:263, 1989.

116. Frazer GS, Rosol TJ, Threlfall WR: Effect of serial intrauterine dimethyl sulfoxide infusions on the incidence of periglandular fibrosis in category ii horse endometria, Theriogenology 29:1091, 1988.

117. Ferris RA, Frisbie DD, McCue PM: Use of mesenchymal stem cells or autologous conditioned serum to modulate the inflammatory response to spermatozoa in mares, Theriogenology 82:36-42, 2014.

118. Corradetti B, Correani A, Romaldini A, et al: Amniotic membrane derived mesemchymal cells and their conditioned media: potential candidates for uterine regenerative therapy in the horse, PLoS ONE 9(10):e111324, 2014, doi:10.1371/journal.pone.0111324.

119. Alvarenga MA, Carmo MT, Segabinazzi LG, et al: Feasibility and safety of endometrial injection of autologous bone marrow mesemchymal stem cells in mares, J Equine Vet Sci 42:12-18, 2016.

Ruminants-Bovine Uterine Infection

1. Martinez J, Thibier M: Reproductive disorders in dairy cattle: I. Respective influence of herds, seasons, milk yield and parity, Theriogenology 21:569,

1984.

2. Ball L, Olson JD, Mortimer RG: Bacteriology of the postpartum uterus, Proc Ann Meeting Soc Theriogenol 164-169, 1984.

3. Sheldon IM, Williams EJ, Miller ANA, et al: Uterine diseases in cattle after parturition, Vet J 176:115, 2008.

4. Olson JD, Ball L: Metritis and pyometra, J Soc Theriogenology 14:65, 1987.

5. Olson JD, Ball L, Mortimer RG: Therapy of postpartum uterine infections, Proc Ann Meeting Soc Theriogenol 170-178, 1984.

6. Bishop JR, Bodine AB, O'Dell GD, et al: Retention data for antibiotics commonly used for bovine infections, J Dairy Sci 67:437, 1984.

7. Kaneene JB, Coe PH, Smith JH, et al: Drug residues in milk after intrauterine injection of oxytetracycline, lincomycin-spectinomycin, and povidone-iodine in cows with metritis, Am J Vet Res 47:1363, 1986.

8. Anderson KL, Moats WA, Rushing JE, et al: Potential for oxytetracycline administration by three routes to cause milk residues in lactating cows, as detected by radioimmunoassay (charm ii) and high-performance liquid chromatography test methods, Am J Vet Res 56:70, 1995.

9. Beagley JC, Whitman KJ, Baptiste KE, et al: Physiology and treatment of retained fetal membranes in cattle, J Vet Intern Med 24:261, 2010.

10. Drillich M, Arlt S, Kersting S, et al: Ceftiofur derivatives in serum, uterine tissues, cotyledons, and lochia after fetal membrane retention, J Dairy Sci 89:3431, 2006.

11. Stephens LR, Slee KJ, Poulton P, et al: Investigation of purulent vaginal discharge in cows, with particular reference to Haemophilus somnus, Aust Vet J 63:182, 1986.

12. Olson JD, Ball L, Mortimer RG, et al: Aspects of bacteriology and endocrinology of cows with pyometra and retained fetal membranes, Am J Vet Res 45:2251, 1984.

13. BonDurant RH: Diagnosis, treatment, and control of bovine trichomoniasis, Compend Contin Educ Pract Vet 7:S179, 1985.

14. McClary D: Metritis. In Howard JL, editor: Current Veterinary Therapy: Food Animal Practice, ed 2, Philadelphia, PA, 1986, WB Saunders, p 775.

15. Tibary A, Fite C, Anouassi A, et al: Infectious causes of reproductive loss in camelids, Theriogenology 66:633, 2006.

16. Eilts BE, Scholl DT, Paccamonti DL, et al: Prevalence of endometrial cysts and their effect on fertility. In Sharp DC, Bazer FW, editors: Equine reproduction VI, Madison, WI, 1995, Society for the Study of Reproduction, pp 527-532.

17. McKinnon AO, Squires EL, Voss JL: Ultrasound evaluation of the mare's reproductive tract—part ii, Compend Contin Educ Pract Vet 9:472, 1987.

18. Burgess J: Correspondence: uterine prolapse in the mare, Vet Rec 96:513, 1975.

19. Odegaard SA: Packed cell-volume (PCV) in connection with uterine prolapse and in parturient paresis in cows, Acta Vet Scand 18:451, 1977.

20. Rowe JD, Van Metre DC: Use of ultrasonography in sheep and goats, Large Anim Proc North Amer Vet Conf 2012. 26 (CD).

Vaginal Abnormailities

1. Pascoe RR: Observations on the length and angle of declination of the vulva and its relation to fertility in the mare, J Reprod Fertil Suppl 27:299,

1979.

2. Brown MP, Colahan PT, Hawkins DL: Urethral extension for treatment of urine pooling in mares, J Am Vet Med Assoc 173:1005, 1978.

3. Monin T: Vaginoplasty: a surgical treatment for urine pooling in the mare, Proc 18th Ann Conv Amer Assoc Eq Pract 18:99-102, 1972.

4. Engels M, Steck F, Wyler R: Comparison of the genomes of infectious bovine rhinotracheitis and infectious pustular vulvovaginitis virus strains by restriction endonuclease analysis, Arch Virol 67:169, 1981.

5. Christensen BW, Troedsson MH, Roberts JF, et al: Theriogenology question of the month. Bleeding varicose veins, J Am Vet Med Assoc 228:1507, 2006.

6. Studdert MJ: Comparative aspects of equine herpesviruses, Cornell Vet 64:94, 1974.

7. Troedsson MHT: Diseases of the external genitalia. In Robinson NE, editor: Current Therapy in Equine Medicine, ed 4, Philadelphia, PA, 1997, Saunders, pp 512-516.

8. Miller RB, Lein DH, McEntee KE, et al: Haemophilus somnus infection of the reproductive tract of cattle: a review, J Am Vet Med Assoc 182:1390, 1983.

9. Mulira GL, Saunders JR, Barth AD: Isolation of Ureaplasma diversum and mycoplasmas from genital tracts of beef and dairy cattle in Saskatchewan, Can Vet J 33:46-49, 1992.

10. Trueblood MS: Relationship of ovine contagious ecthyma and ulcerative dermatosis, Cornell Vet 56:521-526, 1966.

11. Maher JM, Squires EL, Voss JL, et al: Effect of anabolic steroids on reproductive function of young mares, J Am Vet Med Assoc 183:519, 1983.

12. Omara-Opyene AL, Varma S, Ogaa JS, et al: Occurrence of bovine squamous cell carcinoma in Kenya, Kenya Vet 8:5, 1984.

Abortion-Mares

1. Giles RC, Donahue JM, Hong CB, et al: Causes of abortion, stillbirth, and perinatal death in horses: 3,527 cases (1986-1991), J Am Vet Med Assoc 203:1170, 1993.

2. Ginther OJ: Twinning in mares: a review of recent studies, J Equine Vet Sci 2:127, 1982.

3. Ginther OJ, Douglas RH: The outcome of twin pregnancies in mares, Theriogenology 18:237, 1982.

4. Ginther OJ: Using a twinning tree for designing equine twin-prevention programs, J Equine Vet Sci 8:101, 1988.

5. Pascoe DR, Pascoe RR, Hughes JP, et al: Management of twin conceptuses by manual embryonic reduction: comparison of two techniques and three hormone treatments, Am J Vet Res 48:1594, 1987.

6. Veronesi MC, Faustini M, Villani M, et al: Plasma concentrations of 15-ketodihydro-pgf (2alpha), cortisol and progesterone during manual twin reduction in Thoroughbred mares, J Vet Med A Physiol Pathol Clin Med 52:411, 2005.

7. MacPherson ML, Reimer JM: Twin reduction in the mare: current options, Anim Reprod Sci 60:233, 2000.

8. Rantanen NW, Kincaid B 1988. Ultrasound guided fetal cardiac puncture: a method of twin reduction in the mare, pp 173-179. Proceedings of the 34th Annual Convention of the Association of Equine Practitioners, Dec 4-7, San Diego, CA.

9. Wolfsdorf KE, Rodgerson D, Holder R: How to manually reduce twins between 60 and 120 days gestation using cranio-cervical dislocation, Proc 51st Ann Conv Amer Assoc Eq Pract 51:284-287, 2005.

10. Smith KC, Blunden AS, Whitwell KE, et al: A survey of equine abortion, stillbirth and neonatal death in the UK from 1988 to 1997, Equine Vet J 35:496, 2003.

11. Erol E, Sells SF, Williams NM, et al: An investigation of a recent outbreak of nocardioform placentitis caused abortions in horses, Vet Microbiol 158:425, 2012.

12. Christensen BW, Roberts JF, Pozor MA, et al: Nocardioform placentitis with isolation of Amycolatopsis spp. in a Florida-bred mare, J Am Vet Med Assoc 228:1234, 2006.

13. Labeda DP, Donahue JM, Williams NM, et al: Amycolatopsis kentuckyensis sp. Nov., Amycolatopsis lexingtonensis sp. Nov. and Amycolatopsis pretoriensis sp. Nov., isolated from equine placentas, Int J Syst Evol Microbiol 53:1601, 2003.

14. LeBlanc MM, Giguere S, Brauer K, et al: Premature delivery in ascending placentitis is associated with increased expression of placental cytokines and allantoic fluid prostaglandins e-2 and f-2 alpha, Theriogenology 58:841, 2002.

15. Bolin DC, Donahue JM, Vickers ML, et al: Equine abortion and premature birth associated with Cellulosimicrobium cellulans infection, J Vet Diagn Invest 16:333, 2004.

16. Wink JM, Kroppenstedt RM, Ganguli BN, et al: Three new antibiotic producing species of the genus Amycolatopsis, Amycolatopsis balhimycina sp. Nov., Amycolatopsis tolypomycina sp. Nov., Amycolatopsis vancoresmycina sp. Nov., and description of Amycolatopsis keratiniphila subsp. Keratiniphila subsp. Nov. and Amycolatopsis keratiniphila subsp. Nogabecina subsp. Nov, Syst Appl Microbiol 26:38, 2003.

17. Canisso IF, Ball BA, Erol E, et al: Attempts to induce nocardioform placentitis (Crosiella equi) experimentally in mares, Eq Vet J 47:91-95, 2015.

18. Troedsson MHT, Renaudin CD, Zent WW, et al: Transrectal ultra­sonography of the placenta in normal mares and mares with pending abortion: a field study, Proc 43rdAnn Conv Amer AssocEq Pract 43:256-258,

1997.

19. Reef VB, Vaala WE, Worth LT, et al: Ultrasonographic evaluation of the fetus and intrauterine environment in healthy mares during late gestation, Vet Radiol Ultrasound 36:533, 1995.

20. Pipers FS, Adams-Brendemuehl CS: Techniques and applications of transabdominal ultrasonography in the pregnant mare, J Am Vet Med Assoc 185:766, 1984.

21. Pipers FS, Zent W, Holder R, et al: Ultrasonography as an adjunct to pregnancy assessments in the mare, J Am Vet Med Assoc 184:328,

1984.

22. Renaudin CD, Troedsson MH, Gillis CL, et al: Ultrasonographic evaluation of the equine placenta by transrectal and transabdominal approach in the normal pregnant mare, Theriogenology 47:559, 1997.

23. Reef BV, Vaala WE, Worth LT, et al: Ultrasonographic assessment of fetal well-being during late gestation: Development of an equine biophysical profile, Eq Vet J 28:200, 1996.

24. Pashen RL: Maternal and foetal endocrinology during late pregnancy and parturition in the mare, Eq Vet J 16:233, 1984.

25. Rossdale PD, Ousey JC, Cottrill CM, et al: Effects of placental pathology on maternal plasma progestagen and mammary secretion calcium concentra­tions and on neonatal adrenocortical function in the horse, J Reprod Fertil Suppl 44:579, 1991.

26. Stawicki RJ, Ruebel H, Hansen PJ, et al: Endocrinological findings in an experimental model of ascending placentitis in the mare, Theriogenology 58:849, 2002.

27. Sheerin PC, Morris S, Kelleman AA, et al: Diagnostic efficiency of transrectal ultrasonography and plasma progestin profiles in identifying mares at risk for premature delivery, Proc Amer Assoc Eq Pract - Focus in Equine Reproduction 22-23, 2003.

28. Wynn MA, Fedorka C, Ball BA, et al: A prospective case-control study of biomarkers for feto-placental well-being in the mare, Proc 62nd Ann Conv Amer Assoc Eq Pract 62:351-352, 2016.

29. Douglas RH: Endocrine diagnostics in the broodmare: what you need to know about progestins and estrogens, Proc Soc Theriogenol 106-115, 2004.

30. Esteller-Vico A, Ball BA, Troedsson MHT, et al: Endocrine changes, fetal groth, and uterine artery hemodynamics after chronic estrogen suppression during the last trimester of equine pregnancy, Biol Reprod 96:414-423,

2017.

31. Ryan P, Bennet-Wimbush K, Vaala WE, et al: Relaxin as a biochemical marker of placental insufficiency in the horse: a review, Pferdeheilkunde 15:622, 1999.

32. da Silva MAC, Canisso IF, Johnson AEM, et al: Parturition increases serum amyloid A concentration in healthy pregnant mares, Clin Theriogenol 3:355, 2011.

33. Canisso IF, Troedsson MHT, Cray C, et al: Serum amyloid A and haptoglobin concentrations in pregnant mares with experimentally induced placentitis, Proc 58th Ann Conv Amer Assoc Eq Pract 85:524-525, 2012.

34. Murchie TA, MacPherson ML, LeBlanc MM, et al: A microdialysis model to detect drugs in the allantoic fluid of pregnant pony mares, Proc 49th Ann Conv Amer Assoc Eq Pract 49:118-121, 2003.

35. Diaw M, Bailey CS, Schlafer D, et al: Characteristics of endometrial culture and biopsy samples taken immediately postpartum from normal mares compared with those from mares with induced placentitis, Anim Reprod Sci 121S:S369, 2010.

36. Troedsson MHT, Zent WW Clinical ultrasonographic evaluation of the equine placenta as a method to successfully identify and treat mares with placentitis. Proc Ann Workshop on the Equine Placenta, Dec 5-6, Lexington, KY. 2003; 66-67.

37. Graczyk J, MacPherson ML, Pozor MA, et al: Treatment efficacy of tri­methoprim sulfamethoxazole and pentoxifylline in equine placentitis, Anim Reprod Sci 94:434, 2006.

38. Bailey CS, MacPherson ML, Graczyk J, et al: Treatment efficacy of tri­methoprim sulfamethoxazole, pentoxifylline, and altrenogest in equine placentitis, Theriogenology 68:516, 2007.

39. Slater JD, Lunn DP, Horohov DW, et al: Report of the equine herpesvirus-1 Havermeyer workshop, San Gimignano, Tuscany, June 2004, Vet Immunol Immunopathol 111:3, 2006.

40. Ostlund EN: The equine herpesviruses, Vet Clin North Am Equine Pract 9:283, 1993.

41. Acland HM: Abortion in mares. In McKinnon AO, Voss JL, editors: Equine Reproduction, Philadelphia, PA, 1993, Lea & Febiger, pp 554-562.

42. Patel JR, Heldens J: Equine herpesviruses 1 (EHV-1) and 4 (EHV-4)— pidemiology, disease and immunoprophylaxis: A brief review, Vet J 170:14,

2005.

43. Allen GP, Bryans JT: Molecular epizootiology, pathogenesis, and prophy­laxis of equine herpesvirus-1 infections, Prog Vet Microbiol Immunol 2:78,

1986.

44. Gardiner DW, Lunn DP, Goehring LS, et al: Strain impact on equine herpesvirus type 1 (ehv-1) abortion models: viral loads in fetal and placental tissues and foals, Vaccine 30:6564, 2012.

45. Coignoul FL, Cheville NF: Pathology of maternal genital tract, placenta, and fetus in equine viral arteritis, Vet Pathol 21:333, 1984.

46. Del Piero F: Equine viral arteritis, Vet Pathol 37:287, 2000.

47. Timoney PJ, McCollum WH: Equine viral arteritis, Can Vet J 28:693,

1987.

48. Broaddus CC, Balasuriya UBR, White JLR, et al: Evaluation of the safety of vaccinating mares against equine viral arteritis during mid or late gestation or during the immediate postpartum period, J Am Vet Med Assoc 238:741, 2011.

49. Donahue JM, Smith BJ, Redmon KJ, et al: Diagnosis and prevalence of leptospira infection in aborted and stillborn horses, J Vet Diagn Invest 3:148, 1991.

50. Sebastian M, Giles R, Roberts J, et al: Funisitis associated with leptospiral abortion in an equine placenta, Vet Pathol 42:659, 2005.

51. Long MT, Goetz TE, Kakoma I, et al: Evaluation of fetal infection and abortion in pregnant ponies experimentally infected with Ehrlichia risticii, Am J Vet Res 56:1307, 1995.

52. Long MT, Goetz TE, Whiteley HE, et al: Identification of Ehrlichia risticii as the causative agent of two equine abortions following natural maternal infection, J Vet Diagn Invest 7:201, 1995.

53. Long MT, Goetz TE, Kakoma I, et al: Evidence for fetal infectivity and abortion caused by Ehrlichia risticii, Proc 38th Ann Conv Amer Assoc Eq Pract 38:571-577, 1992.

54. Pitel PH, Romand S, Pronost S, et al: Investigation of Neospora sp. antibodies in aborted mares from Normandy, France, Vet Parasitol 118:1, 2003.

55. Cohen ND, Donahue JG, Carey VJ, et al: Case-control study of early-term abortions (early fetal losses) associated with mare reproductive loss syndrome in central Kentucky, J Am Vet Med Assoc 222:210, 2003.

56. Thalheimer R, Lawrence RG The economic loss to the Kentucky equine breeding industry from mare reproductive loss syndrome (mrls) of 2001. [WWW page]. http://cbpa.louisville.edu/eip/Newsletters/research/MRLS. asp, accessed Oct 9, 2009.

57. Webb BA, Barney WE, Dahlman DL, et al: Eastern tent caterpillars (Malacosoma americanum) cause mare reproductive loss syndrome, J Insect Physiol 50:185, 2004.

58. Morehead JP, Blanchard TL, Thompson JA, et al: Evaluation of early fetal losses on four equine farms in central Kentucky: 73 cases (2001), J Am Vet Med Assoc 220:1828, 2002.

59. Dwyer RM, Garber LP, Traub-Dargatz JL, et al: Case-control study of factors associated with excessive proportions of early fetal losses associated with mare reproductive loss syndrome in central Kentucky during 2001, J Am Vet Med Assoc 222:613, 2003.

60. Donahue JM, Sells SF, Bolin DC: Classification of Actinobacillus spp isolates from horses involved in mare reproductive loss syndrome, Am J Vet Res 67:1426, 2006.

61. Daels PF, Stabenfeldt GH, Kindahl H, et al: Prostaglandin release and luteolysis associated with physiological and pathological conditions of the reproductive tract of the mare: A review, Equine Vet J Suppl 8:29, 1989.

Abortion-Ruminants

1. Anderson ML: Infectious causes of bovine abortion during mid- to late- gestation, Theriogenology 68:474, 2007.

2. Roeder PL, Jeffrey M, Cranwell MP: Pestivirus fetopathogenicity in cattle: changing sequelae with fetal maturation, Vet Rec 118:44, 1986.

3. Sprecher DJ, Baker JC, Holland RE, et al: An outbreak of fetal and neonatal losses associated with the diagnosis of bovine viral diarrhea virus, Theriogenol- ogy 36:597, 1991.

4. Hamers C, Dehan P, Couvreur B, et al: Diversity among bovine pestiviruses, Vet J 161:112, 2001.

5. Ross CE, Dubovi EJ, Donis RO: Herd problem of abortions and malformed calves attributed to bovine viral diarrhea, J Am Vet Med Assoc 188:618, 1986.

6. Grahn TC, Fahning ML, Zemjanis R: Nature of early reproductive failure caused by bovine viral diarrhea virus, J Am Vet Med Assoc 185:429, 1984.

7. Bolin SR, McClurkin AW, Cutlip RC, et al: Severe clinical disease induced in cattle persistently infected with noncytopathic bovine viral diarrhea virus by superinfection with cytopathic bovine viral diarrhea virus, Am J Vet Res 46:573, 1985.

8. Baker JC: Bovine viral diarrhea virus: a review, J Am Vet Med Assoc 190:1449,

1987.

9. Munoz-Zanzi CA, Hietala SK, Thurmond MC, et al: Quantification, risk factors, and health impact of natural congenital infection with bovine viral diarrhea virus in dairy calves, Am J Vet Res 64:358, 2003.

10. Munoz-Zanzi CA, Thurmond MC, Hietala SK: Effect of bovine viral diarrhea virus infection on fertility of dairy heifers, Theriogenology 61:1085, 2004.

11. Grooms DL: Reproductive losses caused by bovine viral diarrhea virus and leptospirosis, Theriogenology 66:624-628, 2006.

12. Ellis WA, O’Brien JJ, Bryson DG, et al: Bovine leptospirosis: some clinical features of serovar hardjo infection, Vet Rec 117:101, 1985.

13. Songer JG, Thiermann AB: Leptospirosis, J Am Vet Med Assoc 193:1250,

1988.

14. Ellis WA, O’Brien JJ, Cassells JA, et al: Excretion of Leptospira interrogans serovar hardjo following calving or abortion, Res Vet Sci 39:296, 1985.

15. Kingscote BF, Wilson D: Leptospirosa pomona abortion storm in a cattle herd in Saskatchewan, Can Vet J 27:440, 1986.

16. Dawson LJ: Conditions causing abortions in cattle. I. Introduction, bacterial abortions and mycotic abortions, Agri-Practice 6:7, 1985.

17. Kimsey PB, Kennedy PC, Bushnell RB, et al: Studies on the pathogenesis of epizootic bovine abortion, Am J Vet Res 44:1266, 1983.

18. King DP, Chen CI, Blanchard MT, et al: Molecular identification of a novel deltaproteobacterium as the etiologic agent of epizootic bovine abortion (foothill abortion), J Clin Microbiol 43:604, 2005.

19. Chen CI, King DP, Blanchard MT, et al: Identification of the etiologic agent of epizootic bovine abortion in field-collected Ornithodoros coriaceus koch ticks, Vet Microbiol 120:320, 2007.

20. Osebold JW, Spezialetti R, Jennings MB, et al: Congenital spirochetosis in calves: association with epizootic bovine abortion, J Am Vet Med Assoc 188:371, 1986.

21. Brooks RS, Blanchard MT, Anderson ML, et al: Quantitative duplex taqman real-time polymerase chain reaction for the assessment of the etiologic agent of epizootic bovine abortion, J Vet Diagn Invest 23:1153, 2011.

22. Lane RS, Burgdorfer W, Hayes SF, et al: Isolation of a spirochete from the soft tick, Ornithodoros coriaceus: a possible agent of epizootic bovine abortion, Science 230:85, 1985.

23. Kennedy PC, Casaro AP, Kimsey PB, et al: Epizootic bovine abortion— histogenesis of the fetal lesions, Am J Vet Res 44:1040, 1983.

24. Carvalho Net AV, Mol JPS, Xavier MN, et al: Pathogenesis of bovine brucellosis, Vet J 184:146-155, 2010.

25. Ducrotoy MJ, Munoz PM, Conde-Alvarez R: A systematic review of current immunological tests for the diagnosis of cattle brucellosis, Prev Vet Med 151:57-72, 2018.

26. Songelwayo LC, Scmidt T, Akoi GW: Use of Rrucella abortus species specific polymerase chain reaction for the diagnosis of bovine brucellosis, J South Afr Vet Assoc 88:a1433, 2017, doi:10.4102/jsava.v88i0.1433.

27. Anderson TD, Meador VP, Cheville NF: Pathogenesis of placentitis in the goat inoculated with Rrucella abortus. I. Gross and histologic lesions, Vet Pathol 23:219, 1986.

28. Bosseray N: Rrucella infection and immunity in placenta, Ann Inst Pasteur Microbiol 138:110, 1987.

29. Crawford RP, Williams JD, Huber JD, et al: Biotypes of Rrucella abortus and their value in epidemiologic studies of infected cattle herds, J Am Vet Med Assoc 175:1274, 1979.

30. Catlin JE, Sheehan EJ: Transmission of bovine brucellosis from dam to offspring, J Am Vet Med Assoc 188:867, 1986.

31. Crawford RP, Huber JD, Sanders RB: Brucellosis in heifers weaned from seropositive dams, J Am Vet Med Assoc 189:547, 1986.

32. Nicoletti P, Milward FW, Hoffmann E, et al: Efficacy of long-acting oxytetracycline alone or combined with streptomycin in the treatment of bovine brucellosis, J Am Vet Med Assoc 187:493, 1985.

33. Edmonds MD, Schurig GG, Samartino LE, et al: Biosafety of Rrucella abortus strain RB51 for vaccination of mature bulls and pregnant heifers, Am J Vet Res 60:722, 1999.

34. Van Metre DC, Kennedy GA, Olsen SC, et al: Brucellosis induced by RB51 vaccine in a pregnant heifer, J Am Vet Med Assoc 215:1491-1493, 1999.

35. Sahin O, Yaeger M, Wu Z, et al: Campylobacter-associated diseases in animals, Annu Rev Anim Riosci 5:21-42, 2017.

36. Miller RB, Lein DH, McEntee KE, et al: Haemophilus somnus infection of the reproductive tract of cattle: a review, J Am Vet Med Assoc 182:1390, 1983.

37. Givens MD: A clinical, evidence-based approach to infectious causes of infertility in beef cattle, Theriogenology 66:648, 2006.

38. Thomson MS, Stringfellow DA, Lauerman LH: Adherence of Haemophilus somnus to bovine embryos after in vitro exposure, Am J Vet Res 49:63,

1988.

39. Patterson RM, Mitchell GM, Humphrey JD, et al: Experimental induction of vaginitis in heifers by infection with Haemophilus somnus, Aust Vet J 63:163, 1986.

40. Miller RB, Van Camp SD, Barnum DA: The effects of intra-amniotic inoculation of Haemophilus somnus on the bovine fetus and dam, Vet Pathol 20:574, 1983.

41. Miller RB, Barnum DA: Effects of Haemophilus somnus on the pregnant bovine reproductive tract and conceptus following cervical infusion, Vet Pathol 20:584, 1983.

42. Bundurant BN, Hutchins T, den Bakker HC, et al: Listeriosis outbreak in dairy cattle caused by an unusual Listeria monocytogenes serotype 4b strain, J Vet Diagn Invest 23:155-158, 2011.

43. Kirkbride CA: Mycoplasma, Ureaplasma, and Acholeplasma infections of bovine genitalia, Vet Clin North Am Food Anim Pract 3:575, 1987.

44. Ruffin DC: Mycoplasma infections in small ruminants, Vet Clin N Amer: Food An Pract 17:315-332, 2001.

45. Stalheim OH, Proctor SJ: Experimentally induced bovine abortion with Mycoplasma agalactiae subsp bovis, Am J Vet Res 37:879, 1976.

46. Hinton M: Salmonella abortion in cattle, Vet Annu 26:81, 1986.

47. East NE: Pregnancy toxemia, abortions, and periparturient diseases, Vet Clin North Am Large Anim Pract 5:601, 1983.

48. Hall GA, Jones PW: A study of the pathogenesis of experimental Salmonella dublin abortion in cattle, J Comp Pathol 87:53, 1977.

49. Miller RB, Ruhnke HL, Doig PA, et al: The effects of Ureaplasma diver­sum inoculated into the amniotic cavity in cows, Theriogenology 20:367, 1983.

50. Ball HJ, McCaughey WJ: An examination of the effects of Ureaplasma infection on the fertility of synchronised ewes, Anim Reprod Sci 13:61, 1987.

51. Goodger WJ, Skirrow SZ: Epidemiologic and economic analyses of an unusually long epizootic of trichomoniasis in a large California dairy herd, J Am Vet Med Assoc 189:772, 1986.

52. Fitzgerald PR, Hammond DM, Shupe JL: The role of cultures in immediate and delayed examinations of preputial samples for Trichomonas foetus, Vet Med 49:409, 1954.

53. Michi AN, Favetto PH, Kastelic J: A review of sexually transmitted bovine trichomoniasis and campybacterioisis affecting cattle reproductive health, Theriogenology 85:781-791, 2016.

54. Clavijo A, Erol E, Sneed L, et al: The influence of temperature and simulated transport conditions of diagnostic samples on real-time polymerase chain reaction for the detection of Tritrichomonas foetus DNA, J Vet Diagn Invest 23:982, 2011.

55. Rhyan JC, Stackhouse LL, Quinn WJ: Fetal and placental lesions in bovine abortion due to Tritrichomonas foetus, Vet Pathol 25:350, 1988.

56. Skirrow S, BonDurant R, Farley J, et al: Efficacy of ipronidazole against trichomoniasis in beef bulls, J Am Vet Med Assoc 187:405, 1985.

57. McLoughlin DK: Dimetridazole, a systemic treatment for bovine venereal trichomoniasis. I. Oral administration, J Parasitol 51:835, 1965.

58. McAllister MM, Dubey JP, Lindsay DS, et al: Dogs are definitive hosts of Neospora caninum, Int J Parasitol 28:1473, 1998.

59. Gondim LF, McAllister MM, Pitt WC, et al: Coyotes (Canis Iatrans) are definitive hosts of Neospora caninum, Int J Parasitol 34:159, 2004.

60. Gondim LF: Neospora caninum in wildlife, Trends Parasitol 22:247,

2006.

61. Gondim LF, Gao L, McAllister MM: Improved production of Neospora caninum oocysts, cyclical oral transmission between dogs and cattle, and in vitro isolation from oocysts, J Parasitol 88:1159, 2002.

62. Dubey JP, Buxton D, Wouda W: Pathogenesis of bovine neosporosis, J Comp Pathol 134:267, 2006.

63. Pare J, Fecteau G, Fortin M, et al: Seroepidemiologic study of Neospora caninum in dairy herds, J Am Vet Med Assoc 213:1595, 1998.

64. Thurmond M, Hietala S: Strategies to control Neospora infection in cattle, Rovine Practitioner 29:60, 1995.

65. Fayer R, Dubey JP Sarcocystis induced abortion and fetal death, Proceedings of the Symposium on Transplacental Effects on Fetal Health, Nov 5-6, Bethesda, MD, 1987; 153-164.

66. Dubey JP, Bergeron JA: Sarcocystis as a cause of placentitis and abortion in cattle, Vet Pathol 19:315, 1982.

67. Dubey JP: Impaired protective immunity to sarcocystosis in pregnant dairy goats, Am J Vet Res 44:132, 1983.

68. Foley GL, Schlafer DH: Candida abortion in cattle, Vet Pathol 24:532, 1987.

69. Wohlgemuth K, Knudtson WU: Abortion associated with Mortierella wolfii in cattle, J Am Vet Med Assoc 171:437, 1977.

70. Kirkbride CA, Bicknell EJ, Reed DE, et al: A diagnostic survey of bovine abortion and stillbirth in the northern plains states, J Am Vet Med Assoc 162:556, 1973.

71. McCausland IP, Slee KJ, Hirst FS: Mycotic abortion in cattle, Aust Vet J 64:129, 1987.

72. Fenner F: Reoviridae. In Fenner F, editor: Veterinary Virology, Orlando, FL, 1987, Academic Press, pp 577-593.

73. Plummer PJ: Q fever: A new look at an old disease, Large Anim Proc North Amer Vet Conf 305-307, 2011.

74. Plummer PJ, McClure JT Menzies P, et al: Management of Coxiella burnetii infection in livestock populations and the associated zoonotic risk: A consensus statement, J Vet Intern Med 2018. in press.

75. O’Neill TJ, Sargeant JM, Poljak Z: A systematic review and meta-analysis of phase 1 inactivated vaccines to reduce shedding of Coxiella burnetii from sheep and goats from routes of public health importance, Zoonoses Public Hlth 61:519-533, 2013.

76. Berri M, Rousset E, Champion JL: Goats may experience reproductive failures and shed Coxiella burnetii at two successive parturitions after a Q fever infection, Res Vet Sci 83:47, 2007.

77. Menzies PI: Control of important causes of abortion in sheep and goats, Vet Clin N Amer: Food An Pract 27:81-93, 2011.

78. Anderson KL, Hamoud MM, Urbance JW, et al: Isolation of Campylobacter jejuni from an aborted caprine fetus, J Am Vet Med Assoc 183:90, 1983.

79. Welsh RD: Campylobacter jejuni abortion in a heifer, J Am Vet Med Assoc 185:549, 1984.

80. Hedstrom OR, Sonn RJ, Lassen ED, et al: Pathology of Campylobacter jejuni abortion in sheep, Vet Pathol 24:419, 1987.

81. Sahin O, Plummer PJ, Jordan DM, et al: Emergence of a tetracycline­resistant Campylobacter jejuni clone associated with outbreaks of ovine abortion in the United States, J Clin Microbiol 46:1663-1671, 2008.

81a. Burrough ER, Sahin O, Plummer PJ: Comparison of two commercial ovine Campylobacter vaccines and an experimental bacterin in guinea pigs inoculated with Campylobacter jejuni, Am J Vet Res 72:799-805, 2011.

81b. Blasco JM, Molina-Flores B: Control and eradication of Brucella melitensis infection in sheep and goats, Vet Clin N Amer: Food An Pract 27:95-104, 2011.

82. Ridler AL, West DL: Control of Brucella ovis in sheep, Vet Clin N Amer: Food An Pract 27:61-66, 2011.

83. Ganter M: Zoonotic risks from small ruminants, Vet Microbiol 181:53-65, 2015.

84. Wilsmore AJ, Dawson M, Arthur MJ, et al: The use of a delayed hyper­sensitivity test and long-acting oxytetracycline in a flock affected with ovine enzootic abortion, Br Vet J 142:557, 1986.

85. Greig A, Linklater KA: Field studies on the efficacy of a long acting preparation of oxytetracycline in controlling outbreaks of enzootic abortion of sheep, Vet Rec 117:627, 1985.

86. Dubey JP, Emond JP, Desmonts G, et al: Serodiagnosis of postnatally and prenatally induced toxoplasmosis in sheep, Am J Vet Res 48:1239, 1987.

87. Dubey JP, Kirkbride CA: Epizootics of ovine abortion due to Toxoplasma gondii in north central United States, J Am Vet Med Assoc 184:657, 1984.

88. Rhyan JC, Dubey JP: Ovine abortion and neonatal death due to toxoplasmosis in Montana, J Am Vet Med Assoc 184:661, 1984.

89. Uggla A, Sjoland L, Dubey JP: Immunohistochemical diagnosis of toxoplas­mosis in fetuses and fetal membranes of sheep, Am J Vet Res 48:348, 1987.

90. Dubey JP, Miller S, Desmonts G, et al: Toxoplasma gondii-induced abortion in dairy goats, J Am Vet Med Assoc 188:159, 1986.

91. Munday BL, Dubey JP: Serology of experimental toxoplasmosis in pregnant ewes and their foetuses, Aust Vet J 63:353, 1986.

92. Dubey JP: Toxoplasma gondii cysts in placentas of experimentally infected sheep, Am J Vet Res 48:352, 1987.

Male Reproductive Disorders

1. Walker DF, Vaughan JT: Bovine and equine urogenital surgery, Philadelphia, PA, 1980, Lea & Febiger.

2. Roberts SJ: Veterinary Obstetrics and Genital Diseases (theriogenology), ed 3, Woodstock, VT, 1986, Published by the author.

3. Rossdale SD, Ricketts SW: Equine Stud Farm Medicine, ed 2, Philadelphia, PA, 1980, Lea & Febiger.

4. Blanchard TL, Varner DD, Bretzlaff KN, et al: Testicular degeneration in large animals: Identification and treatment, Vet Med 86:537, 1991.

5. Varner DD, Schumacher J, Blanchard TL, et al: Disease and Management of Breeding Stallions, Goleta, CA., 1991, American Veterinary Publications.

6. Beckett SD, Reynolds TM, Walker DF, et al: Experimentally induced rupture of the corpus cavernosum penis in the bull, Am J Vet Res 35:765, 1974.

7. Wolfe DF, Hudson RS, Walker DF, et al: Failure of penile erection due to a vascular shunt from corpus cavernosum penis to corpus spongiosum penis, J Am Vet Med Assoc 184:1511, 1984.

8. Johnson L, Williams EI: Surgical disorders of the genital tract in the bull, Okla Vet 22:2, 1970.

9. Noordsy JL: Hematoma of the bovine penis: a technique for predicting successful surgical correction, Vet Med Small Anim Clin 76:1581, 1981.

10. Smith MC: The reproductive anatomy and physiology of the male goat. In Morrow DA, editor: Current Therapy in Theriogenology, ed 2, Philadelphia, PA, 1986, WB Saunders, pp 616-618.

11. Bruere AN: Examination of the ram for breeding soundness. In Morrow DA, editor: Current therapy in theriogenology, ed 2, Philadelphia, PA, 1986, WB Saunders, pp 874-880.

12. Smith MC: Infertility in the buck. In Morrow DA, editor: Current Therapy in Theriogenology, ed 2, Philadelphia, PA, 1986, WB Saunders, pp 622-624.

13. McMullan WC: The skin. In Mannsmann RA, McAllister ES, Pratt PW, editors: Equine Medicine and Surgery, ed 3, Santa Barbara, CA., 1982, American Veterinary Publications, pp 789-883.

14. Lagos F, Fitzhugh HA, Jr: Factors influencing preputial prolapse in yearling bulls, J Anim Sci 30:949, 1970.

15. Hardin DK, Bierschwal CJ: Management of preputial injuries in the bull, Bovine Clin 4:7, 1984.

16. Donaldson LE, Aubrey JN: Posthitis and prolapse of the prepuce in cattle, Aust Vet J 36:380, 1960.

17. Brook AH, Southcott WH, Stacy BD: Etiology of ovine posthitis: relationship between ovine posthitis and a causal organism, Aust Vet J 42:9, 1966.

18. Van Metre DC, Rao S, Kimberling CV, et al: Factors associated with failure in breeding soundness examination of Western USA rams, Prev Vet Med 105:118, 2012.

19. Simmons HA, Cox JE, Edwards GB, et al: Paraphimosis in seven debilitated horses, Vet Rec 116:126, 1985.

20. Kenney RM, Hurtgen J, Pierson R, et al: Theriogenology and the equine.

II. The stallion, J Soc Theriogenology 9:1, 1983.

21. Blanchard TL, Schumacher J, Edwards JF, et al: Priapism in a stallion with generalized malignant lymphosarcoma, J Am Vet Med Assoc 198:1043, 1991.

22. Bolz W: The prophylaxis and therapy of prolapse and paralysis of the penis occurring in the horse after administration of neuroleptics, Vet Med Rev (Leverkusen) 4:255, 1970.

23. Ambache N, Killick SW: Species differences in postganglionic motor transmission to the retractor penis muscle, Br J Pharmacol 63:25, 1978.

24. Pearson H, Weaver BMQ: Priapism after sedation, neuroleptanalgesia and anesthesia in the horse, Equine Vet J 10:85, 1978.

25. Lucke JN, Sansom J: Penile erection in the horse after acepromazine, Vet Rec 105:21, 1979.

26. Dorman BW, Schmidt JD: Association of priapism in phenothiazine therapy, J Urol 116:51, 1976.

27. Brinsko SP, Blanchard TL, Varnner DD: How to treat paraphimosis, Proc 53rd Ann Conv Amer Assoc Eq Pract 53:580-582, 2007.

28. Koch C, O’Brien T, Livesey M: How to construct and apply a penile repulsion device (probang) to manage paraphimosis, Proc 55th Ann Conv Amer Assoc Eq Pract 55:338-341, 2009.

29. Arnold CE, Brinsko SP, Love CC, et al: Use of a modified Vinsot technique for partial phallectomy in 11 standing horses, J Am Vet Med Assoc 237:82, 2010.

30. Sharrock AG: Reversal of drug-induced priapism in a gelding by medication, Aust Vet J 58:39, 1982.

31. Blanchard TL: Stallion genital tract pathology, Proc Soc Theriogenol 1987.

32. Blanchard TL, Varner DD, Hurtgen JP, et al: Bilateral seminal vesiculitis and ampullitis in a stallion, J Am Vet Med Assoc 192:525, 1988.

33. Voss JL, Wotowey JL: Hemospermia, Proc18th Ann Conv Amer Assoc Eq Pract 18:103-112, 1972.

34. Schumacher J, Varner DD, Schmitz DG, et al: Urethral defects in geldings with hematuria and stallions with hemospermia, Vet Surg 24:250, 1995.

35. Bridges EE: The use of ivermectin to treat genital cutaneous habronemiasis in a stallion, Compend Cont Educ Pract Vet 7:S94, 1985.

36. Herd RP, Donham RC: Efficacy of ivermectin against cutaneous Draschia and Habronema infections (summer sores) in horses, Am J Vet Res 42:1953, 1981.

37. Stick JA: Amputation of the equine urethral process affected with habro- nemiasis, Vet Med Small Anim Clin 74:1453, 1979.

38. Pascoe RR: The effect of equine coital exanthema on the fertility of mares covered by stallions exhibiting the clinical disease, Aust Vet J 57:111, 1981.

39. Bryans JT, Allen GP: In vitro and in vivo studies of equine “coital” exanthema, Proc Third Int Conf Eq Infect Diseases 322-336, 1973.

40. Gibbs EPJ, Roberts MC, Morris J: Equine coital exanthema in the United Kingdom, Equine Vet J 4:74, 1970.

41. Bryans JT: Herpesviral diseases affecting reproduction in the horse, Vet Clin North Am Large Anim Pract 2:303, 1980.

42. Blanchard TL, Kenney RM, Timoney PJ: Venereal disease, Vet Clin in North Am (Equine Pract) 8:191, 1992.

43. Bowen JM, Tobin N, Simpson RB, et al: Effects of washing on the bacterial flora of the stallion’s penis, J Reprod Fertil Suppl 32:41, 1982.

44. Burns SJ, Simpson RB, Snell JR: Control of microflora in stallion semen with a semen extender, J Reprod Fertil Suppl 23:139, 1975.

45. Cooper WL: Methods of determining the site of bacterial infections in the stallion reproductive tract, Proc Soc Theriogenol 1-4, 1979.

46. Kenney RM, Bergman RV, Cooper WL, et al: Minimum contamination techniques for breeding mares: technique and preliminary findings, Proc 21st Ann Conv Amer Assoc Eq Prac 21:327-336, 1975.

47. Blanchard TL, Varner DD, Love CC, et al: Use of a semen extender containing antibiotic to improve fertility of a stallion with seminal vesiculitis due to Pseudomonas aeruginosa, Theriogenology 28:541, 1987.

48. Johnson TL, Kenney RM, McGee WR, et al: Pseudomonas infection in a stallion: a case report, Proc 26th Ann Conv Amer Assoc Eq Pract 26:111-116,

1980.

49. Studdert MH, Barker CAV, Savan M: Infectious pustular vulvovaginitis (IPV) virus infection of bulls, Am J Vet Res 25:303, 1964.

50. van Oirschot JT: Bovine herpesvirus 1 in semen of bulls and the risk of transmission; a brief review, Vet Quart 17:29, 1995.

51. Wang J, O’Keefe J, Orr D, et al: An international inter-laboratory ring trial to evaluate a real-time PCR assay for the detection of bovine herpesvirus 1 in extended bovine semen, Vet Microbiol 126:11, 2008.

52. Grewal AS, Wells R: Vulvovaginitis of goats due to a herpesvirus, Aust Vet J 63:79, 1986.

53. Tarigan S, Webb RF, Kirkland D: Caprine herpesvirus from balanoposthitis, Aust Vet J 64:321, 1987.

54. Uzal FA, Woods L, Stillian M, et al: Abortion and ulcerative posthitis associated with caprine herpesvirus-1 infection in goats in California, J Vet Diagn Invest 16:478, 2004.

55. McCoy MH, Montgomery DL, Bratanich AC, et al: Serologic and reproduc­tive findings after a herpesvirus-1 abortion storm in goats, J Am Vet Med Assoc 231:1236, 2007.

56. Carrol EJ, Aanes WA, Ball L: Persistent penile frenulum in bulls, J Am Vet Med Assoc 144:747, 1964.

57. Seidel GE,Jr, Foote RH: Motion picture analysis of ejaculation in the bull, J Reprod Fertil 20:313, 1969.

58. Cotchin E: A general survey of tumours in the horse, Equine Vet J 9:16, 1977.

59. Sundberg JP, Burnstein T, Page EH, et al: Neoplasia in equidae, J Am Vet Med Assoc 170:150, 1977.

60. Olson C: Cutaneous papillomatosis and sarcoid. In Catcott EJ, Smithcors JF, editors: Equine Medicine and Surgery, Santa Barbara, CA., 1972, American Veterinary Publications, pp 71-77.

61. Fortier LA, Harg MAM: Topical use of 5-fluorouracil for treatment of squamous cell carcinoma of the external genitalia of horses: 11 cases (1988-1992), J Am Vet Med Assoc 205:1183, 1994.

62. Markel MD, Wheat JD, Jones K: Genital neoplasms treated by en bloc resection and penile retroversion in horses: 10 cases (1977-1986), J Am Vet Med Assoc 192:396, 1988.

63. Olson C, Robl MG, Larson LL: Cutaneous and penile fibropapillomatosis and its control, J Am Vet Med Assoc 153:1189, 1968.

64. Olson D, Jr, Segre D, Skidmore LV: Further observations on immunity to bovine cutaneous papillomatosis, Am J Vet Res 21:233, 1960.

65. Turner CE, Walbornn SR, Blanchard TL, et al: The effect of two levels of hemospermia on stallion fertility, Theriogenology 86:1399-1402, 2016.

66. McDonnell SM: Ejaculation: physiology and dysfunction, Vet Clin North Am Equine Pract 8:57, 1992.

67. Althouse GC, Seager SW, Varner DD, et al: Diagnostic aids for the detection of urine in the equine ejaculate, Theriogenology 31:1141, 1989.

68. Griggers S, Paccamonti DL, Thompson RA, et al: The effect of pH, osmolarity and urine contamination on equine spermatozoal motility, Theriogenology 56:613, 2001.

69. Romano JE, Brinsko S: Reproductive physiology in the male. In Klein DG, editor: Cunningham Textbook of Veterinary Physiology, ed 5, St. Louis, MO, 2013, Elsevier Saunders, pp 451-459.

70. Shore MD, Bretzlaff KN, Thompson JA, et al: Outcome of scrotal hydrocele in bulls, J Am Vet Med Assoc 207:757, 1995.

71. Abbitt B, Fiske RA, Craig TM, et al: Scrotal hydrocele secondary to ascites in 28 bulls, J Am Vet Med Assoc 207:753, 1995.

72. Craig T: Seasonal transmission of bovine gastrointestinal nematodes in Texas Gulf Coast, J Am Vet Med Assoc 174:844, 1979.

73. Blanchard TL: Identification and treatment of scrotal abnormalities in large animals, Vet Med 85:82, 1990.

74. Love CL: Ultrasonographic evaluation of the testis, epididymis, and spermatic cord of the stallion, Vet Clin North Am Equine Pract 8:167, 1992.

75. Hopkins SM, Larsen RE, Drost M, et al: Unilateral castration as treatment for hydrocele in a bull, J Am Vet Med Assoc 178:837, 1981.

76. Gerona GR, Sikes JO: Effects of elevated scrotum temperature on sper­matogenesis and semen characteristic (abstract), J Dairy Sci 53:659, 1970.

77. Ross AD, Entwistle KW: The effect of scrotal insulation on spermatozoal morphology and the rates of spermatogenesis and epididymal passage of spermatozoa in the bull, Theriogenology 11:111, 1979.

78. Ibrahim NM, Romano JE, Troedsson MH, et al: Effect of scrotal insulation on clusterin positive cells in ram semen and their relationship to semen quality, J Androl 22:863, 2001.

79. McEntee K: Pathology of the testis of the bull and stallion, Proc Soc Theriogenol 80-91, 1979.

80. Gygax AP, Donawick WJ, Gledhill BL, et al: Haematocele in a stallion and recovery of fertility following unilateral castration, Equine Vet J 5:128, 1973.

81. Hoagland TA, Ott KM, Dinger JE, et al: Effects of unilateral castration on morphologic characteristics of the testis in one-, two-, and three-year-old stallions, Theriogenology 26:397, 1986.

82. Faulkner LC, Hopwood ML, Masken JF, et al: Scrotal frostbite in bulls, J Am Vet Med Assoc 152:602, 1967.

83. Watt DA: Testicular pathology of Merino rams, Aust Vet J 54:473, 1978.

84. Squires EL, Berndtson WE, Hoyer JH, et al: Restoration of reproductive capacity of stallions after suppression with exogenous testosterone, J Anim Sci 53:1351, 1981.

85. Squires EL, Todter GE, Berndtson WE, et al: Effect of anabolic steroids in reproductive function of young stallions, J Anim Sci 54:576, 1982.

86. Blanchard TL, Elmore RG, Youngquist RS, et al: The effects of stanozolol and boldenone undecylenate on scrotal width, testis weight, and sperm production in pony stallions, Theriogenology 20:121, 1983.

87. Deschamps JC, Ott RS, McEntee K, et al: Effects of zeranol on reproduction in beef bulls: Scrotal circumference, serving ability, and pathological changes of the reproductive organs, Am J Vet Res 48:137, 1987.

88. Ott RS: Current thinking on breeding soundness examination of bulls, Proc Soc Theriogenol 14-31, 1987.

89. Ott RS: Scrotal circumference: how small is too small?, Proc Soc Theriogenol 1-13, 1987.

90. Veeramachaneni DNR, Ott RS, Heath EH, et al: Pathophysiology of small testes in beef bulls: relationship between scrotal circumference, histopatho­logic features of testes and epididymides, seminal characteristics, and endocrine profiles, Am J Vet Res 47:1988-1999, 1986.

91. Kimberling CV, Parsons GA: Breeding soundness evaluation and surgical sterilization of the ram. In Youngquist RS, Trelfall WR, editors: Current Therapy in Large Animal Theriogenology, ed 2, Philadelphia, 1988, Saunders Elsevier, pp 620-628.

92. Coulter GH, Foote RH: Bovine testicular measurements as indicators of reproductive performance and their relationship to productive traits in cattle: a review, Theriogenology 11:297, 1979.

93. Hopkins FM, Spitzer JC: The new Society for Theriogenology Breeding Soundness evaluation system, Vet Clin North Am Food Anim Pract 13:283, 1997.

Cryptorchidism

1. Bishop MSH, David JSE, Messery A: Cryptorchidism in the stallion, Proc Royal Soc Med 59:769, 1966.

2. Leipold HW, DeBowes RM, Bennetts B, et al: Cryptorchidism in the horse: genetic implications, Proc 32nd Ann Conv Amer Assoc Eq Pract 32:579-589, 1985.

3. Hayes HM: Epidemiological features of 5009 cases of equine cryptorchidism, Equine Vet J 18:468, 1986.

4. Warwick BL: Selection against cryptorchidism in Angora goats, J Anim Sci 20:10, 1961.

5. Wheat JD: Cryptorchidism in Hereford cattle, J Hered 52:244, 1961.

6. Kimberling CV: Diseases of rams. In Jensen and Swift' Diseases of Sheep, ed 3, Philaelphia, 1988, Lea and Febiger, pp 3-21.

7. Stickl RL, Fessler JF: Retrospective study of 350 cases of equine cryptor­chidism, J Am Vet Med Assoc 172:343, 1978.

8. The Technical Development Committee: Cryptorchidism, with special reference to the condition in the dog, Vet Rec 66:482, 1954.

9. Kenney RM: Clinical fertility evaluation of the stallion, Proc 21st Ann Conv Amer Assoc Eq Pract 21:336-355, 1975.

10. Blanchard TL, Schumacher J, Taylor TS, et al: Detecting unilateral and bilateral cryptorchidism in large animals, Vet Med 85:395, 1990.

11. Cox JE, Williams JH: Some aspects of the reproductive endocrinology of the stallion and cryptorchid, J Reprod Fertil Suppl 23:75, 1975.

12. Cox JE, Redhead PH, Dawson FE: Comparison of the measurement of plasma testosterone and plasma oestrogens for the diagnosis of cryptor­chidism in the horse, Equine Vet J 18:179, 1986.

13. Claes AN, Ball BA, Almeida J, et al: Detection of serum anti-mullerian hormone concentrations as a method for diagnosis of cryptorchidism in the horse, Proc 57th Ann Conv Amer Assoc Eq Pract 57:56, 2011.

Testicular Degeneration

1. Blanchard TL, Varner DD, Bretzlaff KN, et al: Testicular degeneration in large animals. I, Causes and pathologic changes, Vet Med 86:531, 1991.

2. Johnston JE, Naelappa H, Frye JB, et al: Physiological responses of Holstein, Brown Swiss, and Red Sindhi crossbred bulls to high temperatures and humidities, J Anim Sci 22:432, 1963.

3. Friedman R, Scott M, Heath SE, et al: The effects of increased testicular temperature on spermatogenesis in the stallion, J Reprod Fertil Suppl 44:127, 1991.

4. Ott RS, Heath EH, Bane A: Abnormal spermatozoa, testicular degeneration and varicocele in a ram, Am J Vet Res 43:241, 1982.

5. Threlfall WR, Carleton CL, Robertson J, et al: Recurrent torsion of the spermatic cord and scrotal testis in a stallion, J Am Vet Med Assoc 196:1641, 1990.

6. McEntee K: Pathology of the testis of the bull and stallion, Proc Soc Theriogenol 80-91, 1979.

7. Garcia MC, Ganjam VK, Blanchard TL, et al: The effects of stanozolol and boldenone undecylenate on plasma testosterone and gonadotropins and on testis histology in pony stallions, Theriogenology 28:109, 1987.

8. Hahn J, Foote RH, Seidel GE, Jr: Quality and freezability of semen from growing and aged dairy bulls, J Dairy Sci 52:1843, 1969.

9. Mickelsen WD, Paisely LG, Dahmen JJ: The effect of scrotal circumference and sperm motility and morphology in the ram on conception rates and lambing percentage in the ewe, Theriogenology 16:53, 1981.

10. Thompson DL, Jr, Pickett BW Squires EL, et al: Testicular measurements and reproductive characteristics in stallions, J Reprod Fertil Suppl 27:13, 1979.

11. Burns PJ, Douglas RH: Reproductive hormone concentrations in stallions with breeding problems: case studies, J Equine Vet Sci 5:40, 1985.

12. Byers SW, Glover TD: Effect of scrotal insulation on the pituitary-testicular axis of the ram, J Reprod Fertil 71:23, 1984.

13. Threlfall W: Testicular biopsy, Proc Soc Theriogenol 65-73, 1987.

14. Varner DD, Blanchard TL, Brinsko SP, et al: Techniques for evaluating selected reproductive disorders of stallions, Anim Reprod Sci 60-61:493, 2000.

15. Brinsko SP, Squires EL, Pickett BW, et al: Gonadal and pituitary responsive­ness of stallions is not down-regulated by prolonged pulsatile administration of GnRH, J Androl 19:100, 1998.

16. Blue BJ, Pickett BW, Squires EL, et al: Effect of pulsatile and continuous administration of GnRH on reproductive function of stallions, J Reprod Fertil Suppl 44:145, 1991.

Orchitis

1. Kasaback CM, Rashmir-Raven AM, Black SS: Theriogenology question of the month: Septic orchitis-periorchitis and epididymitis, J Am Vet Med Assoc 215:787-789, 1999.

2. Van Camp SD: Common causes of infertility in the bull, Vet Clin N Amer: Food An Pract 13:203-231, 1997.

3. Gouletsou PG, Fthenakis GC: Microbial diseases of the genital system of rams or bucks, Vet Microbiol 181:130-135, 2015.

Testicular Neoplasia

1. Cotchin E Neoplasms of domesticated mammals: a review, No 4. Com­monwealth Bureau of Animal Health, Bucks, England, 1956.

2. Innes JR: Neoplastic diseases of the testis in animals, J Path Bact 54:485, 1942.

3. Moulton JE: Tumors in domestic animals, ed 2, Berkeley, CA., 1978, University of California Press.

4. Brinsko SP: Neoplasia of the male reproductive tract, Vet Clin North Am Equine Pract 14:517, 1998.

5. Seminoma in the horse: report of two cases, J Equine Med Surg 3:213, 1979.

6. Gelberg HB, McEntee K: Equine testicular interstitial cell tumors, Vet Pathol 24:231, 1987.

7. Stick JA: Teratoma and cyst formation of the equine cryptorchid testicle, J Am Vet Med Assoc 176:211, 1980.

8. Dunn HD, McEntee K: Semen quality and fertility in bulls with testicular tumors, Int J Fertil 9:613, 1964.

Infertility Caused by Diseases of the Spermatic Cord-Torsion of the Spermatic Cord

1. Horney FD, Barker CAV: Torsion of the testicle in a Standardbred, Can Vet J 16:272, 1975.

2. Kenney RM: Clinical fertility evaluation of the stallion, Proc 21st Ann Conv Amer Assoc Eq Pract 21:336-355, 1975.

3. Pascoe JR, Ellenburg TV, Culbertson MR, Jr, et al: Torsion of the spermatic cord in a horse, J Am Vet Med Assoc 178:242, 1981.

4. Wyatt JK, Mundy AB: Torsion of the testicle: a clinical review of 20 cases, Canad Med Assoc J 107:971, 1972.

Varicocele

1. Ott RS, Heath EH, Bane A: Abnormal spermatozoa, testicular degeneration and varicocele in a ram, Am J Vet Res 43:241, 1982.

2. Ezzi A, Ladds PW, Hoffman D, et al: Pathology of varicocele in the ram, Aust Vet J 65:11, 1988.

3. Watson PF: Varicocele in the ram affecting spermatogenesis and sperm maturation, Vet Rec 95:343, 1974.

Infertility Caused by Diseases of the Epididymis and Accessory Sex Glands-Epididymitis

1. McEntee K Pathology of the epididymis.VIII International Congress on Animal Reproduction and Artificial Insemination, Kracow, Poland. 1976, 1186-1188.

2. Brinsko SP, Varner DD, Blanchard TL, et al: Bilateral infectious epididymitis in a stallion, Equine Vet J 24:325, 1992.

3. Walker RL, LeaMaster BR, Stellflug JN, et al: Association of age of ram with distribution of epididymal lesions and etiologic agent, J Am Vet Med Assoc 188:393, 1986.

4. Biberstein EL, McGowan B, Olander H, et al: Epididymitis in rams: studies on pathogenesis, Cornell Vet 54:27, 1964.

5. Blue MG, McEntee K: Epididymal sperm granuloma in a stallion, Equine Vet J 17:248, 1985.

6. Bagley CV, Burrell WC, Esplin GM, et al: Effect of epididymitis on semen quality of rams, J Am Vet Med Assoc 185:876, 1984.

7. Walker RL, LeaMaster BR, Biberstein EL, et al: Serodiagnosis of Histophilus ovis-associated epididymitis in rams, Am J Vet Res 49:208, 1988.

8. Dargatz DA, Smith A, Knight JA, et al: Antimicrobial therapy for rams with Brucella ovis infection of the urogenital tract, J Am Vet Med Assoc 196:605, 1990.

Seminal Vesiculitis (Vesicular Adenitis)

1. Ball L, Young S, Carroll EJ: Seminal vesiculitis syndrome: lesions in genital organs of young bulls, Am J Vet Res 29:1173, 1968.

2. Klug E, Deegen E, Liesk R, et al: The effect of vesiculectomy on seminal characteristics in the stallion, J Reprod Fertil Suppl 27:61, 1979.

3. Sojka JE, Carter GK: Hemospermia and seminal vesicle enlargement in a stallion, Compend Cont Educ Pract Vet 7:S587, 1985.

4. Vandeplassche M, Devoss A: Excretion of Brucella abortus in the semen of a stallion, Vlaams Diergeneesk Tijschr 29:199, 1960.

5. Hoover TR: Bacterial seminal vesiculitis in bulls, Proc Soc Theriogenol 92-98, 1979.

6. Jones TH, Osborne AD, Ashdown RR: Seminal vesiculitis in bulls associated with infection of Actinobacillus actinoides, Vet Rec 76:24, 1964.

7. Blom E, Christensen NO: Seminal vesiculitis in the bull caused by Corynebacterium pyogenes, Nord Vet Med 17:435, 1965.

8. Blom E, Erno H: Mycoplasmosis: infections of the genital organs of bulls, Acta Vet Scand 8:186, 1967.

9. Galloway DB: A study of bulls with the clinical signs of seminal vesiculitis. Clinical, bacteriological and pathological aspects, Acta Vet Scand 5:1, 1964.

10. Karlson AG, Boyd WL: Orchitis and seminal vesiculitis associated with Trichomonas foetus and Corynebacterium pyogenes in a bull, Cornell Vet 31:311, 1941.

11. Morgan BL, Johansoon KR, Emerson EZ: Some Corynebacterium isolated from the genital tract of the bull, MSC Vet 6:68, 1946.

12. Moro EMP, Weiss RDN, Friedich RSC, et al: Aeromonas hydrophila isolated from cases of bovine seminal vesiculitis in south Brazil, J Vet Diagn Invest 11:189, 1999.

13. Blom E: Studies on seminal vesiculitis in the bull. I. Semen examination methods and post-mortem findings, Nord Vet Med 31:193, 1979.

14. Grotelueschen DM, Mortimer RG, Ellis RP: Vesicular adenitis syndrome in beef bulls, J Am Vet Med Assoc 205:874, 1994.

15. Storz J, Carroll EJ, Ball L, et al: Isolation of a psittacosis agent (Chlamydia) from semen and epididymis of bulls with seminal vesiculitis syndrome, Am J Vet Res 29:549, 1968.

16. Mare J, van Rensburg SJ: The isolation of viruses associated with infertility in cattle: a preliminary report, JS Afr Vet Med Assoc 32:201, 1961.

17. Morris DL: Prevention/control of vesicular adenitis in bulls, Proc 15th Tech Conf Art Insem Reprod 15:82-87, 1994.

18. Larson LL, Bartlett DE, Parker WC: Disease incidence in bulls: 1. when examined for use in artificial insemination. II. In environment of a large artificial insemination study, Proc 8th Int Congr Anim Reprod Art Insem 8(-):1473-1478, 1972.

19. Blom E: Studies on seminal vesiculitis in the bull. II. Malformation of the pelvic genital organs as a possible predisposing factor in the pathogeneses of seminal vesiculitis, Nord Vet Med 31:241, 1979.

20. Linhart RD, Parker WC: Seminal vesiculitis in bulls, Comp Cont Edu Vet Pract 10:1428, 1988.

21. Varner DD, Blanchard TL, Brinsko SP: Techniques for evaluating selected reproductive disorders of stallions, Anim Reprod Sci 60-61:493-509, 2000.

22. Ball L, Griner LA, Carroll EJ: The bovine seminal vesiculitis syndrome, Am J Vet Res 25:291, 1964.

23. Weber JA, Hilt CJ, Woods GL: Ultrasonography appearance of bull accessory sex glands, Theriogenology 29:1347, 1988.

24. Mickelsen WD, Weber JA, Memon MA: Use of transrectal ultrasound for the detection of seminal vesiculitis in a bull, Vet Rec 135:14, 1994.

25. Faulkner LC, Hopwood ML, Wiltbank JN: Seminal vesiculectomy in bulls. II. Seminal characteristics and breeding trials, J Reprod Fertil 16:171, 1968.

26. King GJ, McPherson JW: Influence of seminal vesiculectomy on bovine semen, J Dairy Sci 52:1837, 1969.

27. Romano JE New aseptic technique of semen collection for microbiological culture in bulls. Proceedngs, World Buiatric Conference (Sapporo-Japan). 2018 (in press).

28. Winningham DG, Nemoy NJ, Stamey TA: Diffusion of antibiotics from plasma into prostatic fluid, Nature 219:139, 1968.

29. Hull BL, Monke DR, Rohde R: A new technique for seminal vesiculectomy, Proc 14th Tech ConfArt Insem Reprod 14:100-103, 1992.

30. Hooper RN, Taylor TS, Blanchard TL, et al: Ventral pararectal approach to the seminal vesicles of bulls, JAm Vet Med Assoc 205:596, 1994.

31. Monke DR: Bovine seminal vesiculitis, Proc 10th Tech ConfArt Insem Reprod 10:54-61, 1984.

32. Hoover TR: A technique for injecting into the seminal vesicles of the bull, Am J Vet Res 35:1135, 1974.

33. Martinez MF, Barth AD: Early detection and treatment of vesicular adenitis in bulls, Anim Reprod Sci 101:252, 2007.

34. Martinez MF, Arteaga AA, Barth AD: Intraglandular injection of antibiotics for the treatment of vesicular adenitis in bulls, Anim Reprod Sci 104:201, 2008.

35. Larson RL: Diagnosing and controlling seminal vesiculitis in bulls, Vet Med 92:1073, 1997.

36. Alexander FCM, Zemjanis R, Graham EF, et al: Semen characteristics and chemistry from bulls before and after seminal vesiculectomy and after vasectomy, J Dairy Sci 54:1530, 1971.

Blockage of the Efferent Ducts (Sperm Stasis)

1. Little TV, Woods GL: Ultrasonography of accessory sex glands in stallions, J Reprod Fertil Suppl 35:87, 1987.

2. Klug E, Deegen E, Lazarz B, et al: Effect of adrenergic neurotransmitters upon the ejaculatory process in the stallion, J Reprod Fertil Suppl 32:31, 1982.

3. Held JP, Prater P, Toal RL, et al: Sperm granuloma in a stallion, JAm Vet Med Assoc 194:267, 1989.

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Source: Smith Bradford P., Van Metre David C., Pusterla Nicola (eds.). Large Animal Internal Medicine. Part 2. 6th edition. — Elsevier,2020. — 2279 p.. 2020

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