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Contents

Section I The Cell

Stevetv K. Heidemaiuv

Chapter The Molecular and Cellular Basis of Physiological Regulation, 1

Clinical Correlations:

Peripheral Edema, 32

Chapter 2 Cancer: a Disease of Cellular Proliferation, Life Span, and Death, 34

Clinical Correlations:

Dog That Collapsed While Running, 55

Section Il Neurophysiology_________________________________________________

Bradley Q.

KleLtt, Jantes Q. Cwutittgkant

chapter 3 Introduction to the Nervous System, 60

Clinical Correlations:

Neurologic Disease in a Horse, 64

Chapter 4 The Neuron, 66

Clinical Correlations:

Hypoglycemia, 72

Chapter The Synapse, 74

Clinical Correlations:

Myasthenia Gravis, 79

Chapter 6 The Physiology of Muscle, 81

Clinical Correlations:

Down Cow After Calving, 88

Chapter 7 The Concept of a Reflex, 91

Clinical Correlations:

Trauma in a Foal, 94

Chapter Skeletal Muscle Receptor Organs, 96

Clinical Correlations:

Femoral Nerve Mononeuropathy, 100

Chapter The Concept of Lower and Upper Motor Neurons and Their Malfunction, 102

Clinical Correlations:

Lower Motor Neuron Disease, 104

Upper Motor Neuron Disease, 104

Chapter 1G The Central Control of Movement, 106

Clinical Correlations:

Focal Lesion of the Motor Cortex, 117

Chapter The Vestibular System, 119

Clinical Correlations:

Vestibular Syndrome, 126

Chapter The Cerebellum, 128

Clinical Correlations:

Cerebellar Hypoplasia, 133

Newborn Calf Unable to Rise, 134

Chapter The Autonomic Nervous System and Adrenal Medulla, 136

Clinical Correlations:

Horner’s Syndrome, 143

Chapter The Visual System, 145

Clinical Correlations:

Homonymous Hemianopia, 152

chapter Cerebrospinal Fluid and the Blood-Brain Barrier, 154

Clinical Correlations:

Increased Intracranial Pressure, 159

Seizures in a Foal, 159

Chapter The Electroencephalogram and Sensory-Evoked Potentials, 161

Clinical Correlations:

Brain Tumor, 167

Chapter Hearing, 169

Clinical Correlations:

Congenita) Deafness, 174

Section III Cardiovascular Physiology

Robert B.

Stepkeruon,

Chapter 18 Overview of Cardiovascular Function, 178

Clinical Correlations:

Lethargic Kid Goat, 190

Colic and Endotoxic Shock in Horse Secondary to Strongylus Parasitism, 191

Chapter Electrical Activity of the Heart, 193

Clinical Correlations:

Third-Degree Atrioventricular Block, 210

Chapter 20 The Electrocardiogram, 213

Clinical Correlations:

Dilative Cardiomyopathy with Paroxysmal Atrial Tachycardia, 223

diopter The Heart as a Pump, 226

Clinical Correlations:

Pulmonic Stenosis, 238

Older Horse with Exercise Intolerance, 239

diopter 22 The Systemic and Pulmonary Circulations, 242

Clinical Correlations:

Canine Heartworm Disease with Pulmonary Embolism, 253

Dummy Foal: Hypoxemic Ischemic Encephalopathy, 253

Chapter Capillaries and Fluid Exchange, 255

Clinical Correlations:

Acute Protein-Losing Enteropathy in a Horse, 264

Cl1Mpter 24 Local Control of Blood Flow, 267

Clinical Correlations:

Patent Ductus Arteriosus, 273

Clapter Neural and Hormonal Control of Blood Pressure and Blood Volume, 276

Clinical Correlations:

Intraoperative Hemorrhage, 284

CiiApter Integrated Cardiovascular Responses, 286

Clinical Correlations:

Exercise Intolerance Secondary to Congestive Heart Failure, 294

Cow with “Hardware Disease,” 295

Section IV Gastrointestinal Physiology and Metabolism

Thowas H. Herdt

Chapter Regulation of Gastrointestinal Function, 300

Chapter 28 Movements of the Gastrointestinal Tract, 311

Clinical Correlations:

Equine Rabies, 324

Chzpter Secretions of the Gastrointestinal Tract, 327

Clinical Correlations:

Horse in Pain with Weight Loss, 335

Chapter 30 Digestion and Absorption: the Nonfermentative Processes, 337

Clinical Correlations:

Diarrhea with Dehydration and Acidosis in a Calf, 362 Juvenile Pancreatic Atrophy in a Dog, 362

Chψter 31 Digestion: the Fermentative Processes, 364

Clinical Correlations:

Grain Engorgement Toxemia, 387 Impaction Colic, 387

Chapter 32 Postabsorptive Nutrient Utilization, 389

Clinical Correlations:

Hepatic Lipidosis in a Cat, 406

DehorcdvS. Qreco, Qeorge H.

Stabenfeldt

Chapter 3 3 The Endocrine System, 410

Clinical Correlations:

Equine Cushing’s Disease, 426

Chapter 3 Endocrine Glands and Their Function, 428

Clinical Correlations:

Diabetes Mellitus, 463

Section Vl Reproduction and Lactation________________________________________________________

Aatanm P. Dcundsokv, Qeorge H. Stabenfeldt Chapter 40 by Steuen P. Brinsko

Chapter 3b Control of Gonadal and Gamete Development, 466

Clinical Correlations:

Androgen Insensitivity, 473

Chapter Control of Ovulation and the Corpus Luteum, 475

Clinical Correlations:

Inability to Impregnate a Mare, 480

Persistent Luteal Phase in the Mare, 481

Chapter 3 7 Reproductive Cycles, 483

Clinical Correlations:

Sexual Attractiveness in the Spayed Bitch, 490

Chapter Pregnancy and Parturition, 492

Clinical Correlations:

Prolonged Gestation, 498

Chapter The Mammary Gland, 501

Clinical Correlations:

Pregnant Mare That Does Not Have Sufficient Milk or Udder Development, 514

Neonatal Isoerythrolysis, 515

Chapter Reproductive Physiology of the Male, 517

Clinical Correlations:

Infertility in a Stallion, 524

Section Vll Renal Physiology

Jilt J√. Verlander

Chapter GlomeruIar Filtration, 528

Clinical Correlations:

Chronic Renal Failure, 535

Glomerulonephritis, 535

Chapter 42 Solute Reabsorption, 537

Clinical Correlations:

Glucosuria, 546

Hypoadrenocorticism, 546

diopter 43 Water Balance, 548

Clinical Correlations:

Diabetes Insipidus, 553

Chronic Renal Insufficiency, 554

Citapter 44 Acid-Base Balance, 556

Clinical Correlations:

Respiratory Acidosis Withwith Renal Compensation, 562 Metabolic Alkalosis Withwith Paradoxical Aciduria, 562

Section Vlll Respiratory Function

∕√. Edamrd RobiitsoKr

Chapter 45 Overview of Respiratory Function: Ventilation of the Lung, 566

Clinical Correlations:

Lung Fibrosis in the Dog, 575 Chronic Airway Disease in the Horse, 575

CttMpter 46 Pulmonary Blood Flow, 578

Clinical Correlations:

Brisket Disease in a Heifer, 583

Chapter 47 Gas Exchange, 586

Clinical Correlations:

Hypoventilation in a Bulldog, 592

Hypoxemia in an Anesthetized Clydesdale Horse, 593

Ctiapter 48 Gas Transport in the Blood, 595

Clinical Correlations:

Flea Infestation in a Cat, 600

Atrial Fibrillation in a Horse, 601

Chapter 49 Control of Ventilation, 603

Clinical Correlations:

Hypoxemia with Hyperventilation in an 8-Month-Old Samoyed, 608 Hypoventilation in an Anesthetized Saint Bernard, 609

Chapter 50 Nonrespiratory Functions of the Lung, 611

Clinical Correlations:

Pleuritis in a Thoroughbred Horse, 616

Mitral Insufficiency in a Dog, 617

Section IX Homeostasis

N.

Edamrd Robutsoit

Chapter 51 Fetal and Neonatal Oxygen Transport, 620

Clinical Correlations:

Patent Ductus Arteriosus in a Pomeranian, 625

Chapter 2 Acid-Base Homeostasis, 627

Clinical Correlations:

Upper Airway Obstruction in a Boston Terrier, 635 Torsion of the Abomasum in a Cow, 635 Neonatal Diarrhea in a Foal, 635

Chapter Thermoregulation, 639 Clinical Correlations:

Influenza in Pigs, 649 Heat Stroke in a Boston Terrier, 649

Section X The Immune System

S. Amar AfwteaL, QerkarcLt Q. Sckuriy

Chapter Antigens and Innate Immunity, 652

Clinical Correlations:

Swollen Lymph Nodes in a Colt, 659

chapter The Specific Immune Response: Acquired Immunity, 661

Clinical Correlations:

Unthrifty Foal, 669

Clinical Correlations

EdlterLbySkaroKaCj. Witonsky

SECTION

StewvR. HeidwuM¼

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Source: Cunningham J.G., Klein B.G.. Textbook of Veterinary Physiology. Elsevier Health Sciences,2007. — 720 ð.. 2007

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