Hormonal Conditions Direct the Distribution of Very-Low-Density Lipoprotein Fatty Acids in the Body

During the absorptive phase, VLDLs are directed to adipose tissue by the action of adipose tissue LPL, an insulin- stimulated enzyme. LPL also exists in muscle tissue, but does not depend on insulin stimulation for activity. Thus, during periods of low glucose availability, adipose tissue LPL is inhib­ited because of a lack of insulin, but muscle tissue LPL is fully active. This situation leads to the selective direction of VLDL fatty acids to muscle tissue during times of adipose mobilization.

carbons from the acetyl CoA are converted to carbon dioxide. No new Oxaloacetate can be produced by this process.