Metabolism at the Tissue Level Is Coordinated with Hepatic Metabolism and Results in the Deposition of Fuel into Storage Tissues During the Absorptive Period

The overall effects of hepatic metabolism during the absorption of a meal are the removal of glucose and amino acids and the synthesis of protein and fat. Complementary changes occur in peripheral tissues, so additional glucose and amino acids are removed by skeletal muscle and adipose tissue. In addition, fatty acids secreted by the liver as VLDL triglycerides are deposited in adipose tissue, as are the triglycerides of chylomicrons.