PRACTICE QUESTIONS

1. The major force favoring filtration across the glomerular capillary wall is the:

a. Oncotic pressure of the plasma

b. Oncotic pressure of the glomerular filtrate

c. Hydrostatic pressure of the blood

d.

e. Ultrafiltration coefficient

2. The glomerular filtration rate (GFR) is the:

a. Volume of blood filtered by the kidneys per minute per kilogram of body weight

b. Volume of plasma filtered by the kidneys per minute per kilogram of body weight

c. Volume of urine produced by the kidneys per minute per kilogram of body weight

d. Volume of glomerular filtrate formed by the kidneys per minute per kilogram of body weight

e. Volume of blood cleared of creatinine by the kidneys per minute per kilogram of body weight

3. In clinical practice the GFR is often estimated by deter­mining the rate of creatinine clearance. The rate of creatinine clearance is the:

a. Volume of plasma cleared of creatinine per minute per kilogram of body weight

b. Volume of glomerular filtrate formed per minute per kilogram of body weight

c. Weight of creatinine filtered from the blood per minute per kilogram of body weight

d. Weight of creatinine per volume of urine formed per minute per kilogram of body weight

e. Difference between the rate of plasma flow in the afferent and efferent arterioles

4. The two major characteristics that determine whether a blood component is filtered or retained in the capillary lumen are its:

a. Molecular radius and molecular weight

b. Molecular radius and lipid solubility

c. Molecular radius and plasma concentration

d. Molecular radius and electrical charge

e. Molecular weight and length

5. The GFR is increased by:

a. Λ lovv-protcin meal

b. Afferent arteriolar constriction

c. Tubuloglomerular feedback

d. Release of atrial natriuretic peptide

e. Activation of the renin-angiotensin-aldosterone system