PRACTICE QUESTIONS
1. Which of the following statements is correct in regard to macrophages?
a. They are the first type of cells to appear in circulation and can repeatedly phagocytose in response to invasion by microbial antigens.
b. They secrete antiinflammatory cytokines that prevent fever.
c. They have class 1 major histocompatibility complex (MHC) antigens, and selected macrophages also have class Il MHC antigens and thus can serve as antigen-presenting cells.
d. They have no ability to secrete proteins.
e. They are actually lymphocytes.
2. Wliich of the following is correct about neutrophils?
a. They can rapidly destroy antigen by phagocytosis and respiratory burst.
b. They are lymphocytes that are the first cells to destroy antigens.
c. They are major producers of IL-1.
d. They are efficient antigen-processing cells.
e. All the above.
3. Antigen-presenting cells (APCs) include which of the following?
a. Dendritic cells
b. Selected macrophages
c. B cells
d. T cells
e. Answers a, b, and c
4. Which of the following is correct with regard to antigen?
a. Highly degradable proteins and large, inert substances are not good antigens (i.e., not able to induce a strong immune response).
b. Large molecules are good antigens, and therefore large molecules such as polysaccharides, with simple repeating sugars, are good antigens.
c. Large complex proteins (especially foreign antigens) are good at inducing immune responses.
d. Antigens do not drive an immune response.
e. Lipids, but not lipoproteins, are excellent antigens.