VOCABULARY
This chapter is unusual in that it contains a large number of vocabulary words that are specialized for cancer and related topics, words that generally will not be used in later chapters.
You should be familiar with these vocabulary words, and you should be able to define them and stale their role in normal cells, and whether and how they differ in cancer cells.anchorage dependence of growth
aneuploidy
angiogenesis
apoptosis (intrinsic pathway and extrinsic pathway)
Bcl family
cachexia
caspase(s) (activating and executioner)
cell cycle (G1 phase, S phase, G2 phase, M phase) checkpoint
cyclin
cyclin-dependent kinase (CDK) extravasation
gain-of-function mutation
germ line
intravasation
loss-of-function mutation
MAP kinase pathway
MDR phenotype
metastasis
metastatic cascade
| oncogenes p53 primary tumor Ras retinoblastoma (pRB) somatic cells somatic mutation | stem cells telomerase telomeres tumor suppressor Vasculogenesis VEGF |
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