Information from Central and Peripheral Meat-Sensitive Neurons Is Integrated in the Hypothalamus to Regulate Heat-Losing or Heat- Conserving Mechanisms
Figure 53-6 shows the feedback control mechanisms for the regulation of body temperature. Ontral integration of the information from various receptors occurs in the anterior hypothalamus.
Information from central temperature receptors seems to predominate over information from skin and visceral receptors. For this reason, a rise in core temperature of only ().5o C causes a sevenfold increase in the amount of skin blood flow; similarly, a modest decrease in core temperature initiates vasoconstriction and shivering. The effect of central receptors is about 20-fold greater than the effect of peripheral receptors.In the regulation of body temperature, the hypothalamus behaves as if it has a normal set point. When the core temperature rises above the set point, heat-losing mechanisms are initiated; when temperature decreases, heat conservation or production begins. Information from peripheral receptors modifies the set point, and thus shivering begins at a higher core temperature when the skin is cool than when it is warm. Similarly, sweating is initiated at a higher core temperature when the skin is cool than when it is warm.
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